Effect of naturally random allocation to lower low-density lipoprotein cholesterol on the risk of coronary heart disease mediated by polymorphisms in NPC1L1, HMGCR, or both: a 2 × 2 factorial Mendelian randomization study (Q86927304)

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scientific article published on 11 March 2015

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English	Effect of naturally random allocation to lower low-density lipoprotein cholesterol on the risk of coronary heart disease mediated by polymorphisms in NPC1L1, HMGCR, or both: a 2 × 2 factorial Mendelian randomization study	scientific article published on 11 March 2015

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25770315 AND SRC:MED&resulttype=core&format=json

2 March 2020

Effect of naturally random allocation to lower low-density lipoprotein cholesterol on the risk of coronary heart disease mediated by polymorphisms in NPC1L1, HMGCR, or both: a 2 × 2 factorial Mendelian randomization study (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25770315 AND SRC:MED&resulttype=core&format=json

2 March 2020

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coronary artery disease

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5

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Robert D Brook

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2 March 2020

Brian A. Ference

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Brian A Ference

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2 March 2020

author name string

Faisal Majeed

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2 March 2020

Raju Penumetcha

3

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2 March 2020

John M Flack

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2 March 2020

publication date

11 March 2015

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2 March 2020

Journal of the American College of Cardiology

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2 March 2020

65

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2 March 2020

15

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2 March 2020

1552-1561

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Europe PubMed Central

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2 March 2020

Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans

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https://pubmed.ncbi.nlm.nih.gov/25770315

12 December 2020

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inferred from PubMed ID database lookup

Lipid lowering with PCSK9 inhibitors

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https://pubmed.ncbi.nlm.nih.gov/25770315

12 December 2020

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The target of ezetimibe is Niemann-Pick C1-Like 1 (NPC1L1)

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https://pubmed.ncbi.nlm.nih.gov/25770315

12 December 2020

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Niacin in patients with low HDL cholesterol levels receiving intensive statin therapy

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https://pubmed.ncbi.nlm.nih.gov/25770315

12 December 2020

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An integrated map of genetic variation from 1,092 human genomes

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https://pubmed.ncbi.nlm.nih.gov/25770315

12 December 2020

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Inactivating mutations in NPC1L1 and protection from coronary heart disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/25770315

12 December 2020

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Rationale and design of IMPROVE-IT (IMProved Reduction of Outcomes: Vytorin Efficacy International Trial): comparison of ezetimbe/simvastatin versus simvastatin monotherapy on cardiovascular outcomes in patients with acute coronary syndromes

1 reference

https://pubmed.ncbi.nlm.nih.gov/25770315

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The NCBI dbGaP database of genotypes and phenotypes

1 reference

https://pubmed.ncbi.nlm.nih.gov/25770315

12 December 2020

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Lipid-altering efficacy of ezetimibe plus statin and statin monotherapy and identification of factors associated with treatment response: a pooled analysis of over 21,000 subjects from 27 clinical trials.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25770315

12 December 2020

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Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170,000 participants in 26 randomised trials

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https://pubmed.ncbi.nlm.nih.gov/25770315

12 December 2020

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Evaluating cardiovascular event reduction with ezetimibe as an adjunct to simvastatin in 18,144 patients after acute coronary syndromes: final baseline characteristics of the IMPROVE-IT study population

1 reference

https://pubmed.ncbi.nlm.nih.gov/25770315

12 December 2020

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Blood cholesterol and vascular mortality by age, sex, and blood pressure: a meta-analysis of individual data from 61 prospective studies with 55,000 vascular deaths

1 reference

https://pubmed.ncbi.nlm.nih.gov/25770315

12 December 2020

based on heuristic

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Effect of long-term exposure to lower low-density lipoprotein cholesterol beginning early in life on the risk of coronary heart disease: a Mendelian randomization analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/25770315

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biological, clinical and population relevance of 95 loci for blood lipids

1 reference

https://pubmed.ncbi.nlm.nih.gov/25770315

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of combination lipid therapy in type 2 diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/25770315

12 December 2020

based on heuristic

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Large-scale association analysis identifies new risk loci for coronary artery disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/25770315

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of extended-release niacin with laropiprant in high-risk patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/25770315

12 December 2020

based on heuristic

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Mendelian randomization: Using genes as instruments for making causal inferences in epidemiology

1 reference

https://pubmed.ncbi.nlm.nih.gov/25770315

12 December 2020

based on heuristic

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Major lipids, apolipoproteins, and risk of vascular disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/25770315

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Discovery and refinement of loci associated with lipid levels

1 reference

https://pubmed.ncbi.nlm.nih.gov/25770315

12 December 2020

based on heuristic

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A flexible and accurate genotype imputation method for the next generation of genome-wide association studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/25770315

12 December 2020

based on heuristic

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Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study

1 reference

https://pubmed.ncbi.nlm.nih.gov/25770315

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.JACC.2015.02.020

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25770315 AND SRC:MED&resulttype=core&format=json

2 March 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25770315 AND SRC:MED&resulttype=core&format=json

2 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25770315 AND SRC:MED&resulttype=core&format=json

2 March 2020

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