BACE1 modulates gating of KCNQ1 (Kv7.1) and cardiac delayed rectifier KCNQ1/KCNE1 (IKs) (Q86436522)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26454161 AND SRC:MED&resulttype=core&format=json

26 February 2020

title

BACE1 modulates gating of KCNQ1 (Kv7.1) and cardiac delayed rectifier KCNQ1/KCNE1 (IKs) (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26454161 AND SRC:MED&resulttype=core&format=json

26 February 2020

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26454161 AND SRC:MED&resulttype=core&format=json

26 February 2020

Michael Schwake

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26454161 AND SRC:MED&resulttype=core&format=json

26 February 2020

Tobias Huth

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26454161 AND SRC:MED&resulttype=core&format=json

26 February 2020

11

Christian Alzheimer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26454161 AND SRC:MED&resulttype=core&format=json

26 February 2020

author name string

Marianne Agsten

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26454161 AND SRC:MED&resulttype=core&format=json

26 February 2020

Sabine Hessler

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26454161 AND SRC:MED&resulttype=core&format=json

26 February 2020

Tilmann Volk

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26454161 AND SRC:MED&resulttype=core&format=json

26 February 2020

Andrea Rittger

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26454161 AND SRC:MED&resulttype=core&format=json

26 February 2020

Stephanie Hartmann

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26454161 AND SRC:MED&resulttype=core&format=json

26 February 2020

Christian Raab

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26454161 AND SRC:MED&resulttype=core&format=json

26 February 2020

Doo Yeon Kim

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26454161 AND SRC:MED&resulttype=core&format=json

26 February 2020

Teja W Groemer

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26454161 AND SRC:MED&resulttype=core&format=json

26 February 2020

publication date

8 October 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26454161 AND SRC:MED&resulttype=core&format=json

Journal of Molecular and Cellular Cardiology

26 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26454161 AND SRC:MED&resulttype=core&format=json

26 February 2020

volume

89

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26454161 AND SRC:MED&resulttype=core&format=json

26 February 2020

issue

Pt B

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26454161 AND SRC:MED&resulttype=core&format=json

26 February 2020

page(s)

335-348

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26454161 AND SRC:MED&resulttype=core&format=json

Properties of KvLQT1 K channel mutations in Romano-Ward and Jervell and Lange-Nielsen inherited cardiac arrhythmias

26 February 2020

cites work

1 reference

https://api.crossref.org/works/10.1016/J.YJMCC.2015.10.006

Oestrogen promotes KCNQ1 potassium channel endocytosis and postendocytic trafficking in colonic epithelium

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YJMCC.2015.10.006

K(V)LQT1 and lsK (minK) proteins associate to form the I(Ks) cardiac potassium current

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YJMCC.2015.10.006

Delayed rectifier K( ) currents and cardiac repolarization.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YJMCC.2015.10.006

Driving with no brakes: molecular pathophysiology of Kv7 potassium channels

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YJMCC.2015.10.006

Voltage‐dependent inactivation of the human K channel KvLQT1 is eliminated by association with minimal K channel (minK) subunits

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YJMCC.2015.10.006

The KCNE Tango - How KCNE1 Interacts with Kv7.1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YJMCC.2015.10.006

Structural determinants and biophysical properties of HERG and KCNQ1 channel gating

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YJMCC.2015.10.006

Stoichiometry of the Slow Iks Potassium Channel in Human Embryonic Stem Cell-Derived Myocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YJMCC.2015.10.006

Individual IKs channels at the surface of mammalian cells contain two KCNE1 accessory subunits

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YJMCC.2015.10.006

BACE1 and presenilin/γ-secretase regulate proteolytic processing of KCNE1 and 2, auxiliary subunits of voltage-gated potassium channels

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YJMCC.2015.10.006

Secretome protein enrichment identifies physiological BACE1 protease substrates in neurons

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YJMCC.2015.10.006

BACE1 deficiency causes altered neuronal activity and neurodegeneration

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YJMCC.2015.10.006

Bace1 and Neuregulin-1 cooperate to control formation and maintenance of muscle spindles

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YJMCC.2015.10.006

BACE1-/- mice exhibit seizure activity that does not correlate with sodium channel level or axonal localization

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YJMCC.2015.10.006

The Alzheimer's β-secretase enzyme BACE1 is required for accurate axon guidance of olfactory sensory neurons and normal glomerulus formation in the olfactory bulb

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YJMCC.2015.10.006

Control of peripheral nerve myelination by the beta-secretase BACE1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YJMCC.2015.10.006

Genetic and biochemical evidence for a functional role of BACE1 in the regulation of insulin mRNA expression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YJMCC.2015.10.006

Function, therapeutic potential and cell biology of BACE proteases: current status and future prospects

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YJMCC.2015.10.006

beta Subunits of voltage-gated sodium channels are novel substrates of beta-site amyloid precursor protein-cleaving enzyme (BACE1) and gamma-secretase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YJMCC.2015.10.006

Phenotypic and biochemical analyses of BACE1- and BACE2-deficient mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YJMCC.2015.10.006

Non-proteolytic effect of beta-site APP-cleaving enzyme 1 (BACE1) on sodium channel function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YJMCC.2015.10.006

β-Site APP-cleaving enzyme 1 (BACE1) cleaves cerebellar Na channel β4-subunit and promotes Purkinje cell firing by slowing the decay of resurgent Na current

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YJMCC.2015.10.006

Voltage-dependent Na channels as targets of BACE1 - implications for neuronal firing and beyond

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YJMCC.2015.10.006

BACE1 regulates voltage-gated sodium channels and neuronal activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YJMCC.2015.10.006

β-Secretase BACE1 regulates hippocampal and reconstituted M-currents in a β-subunit-like fashion.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YJMCC.2015.10.006

Gene dosage-dependent rescue of HSP neurite defects in SPG4 patients' neurons

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YJMCC.2015.10.006

Aldosterone upregulates Ca(2 ) current in adult rat cardiomyocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YJMCC.2015.10.006

Structure-based design of potent and selective cell-permeable inhibitors of human beta-secretase (BACE-1).

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YJMCC.2015.10.006

Simulation of the undiseased human cardiac ventricular action potential: model formulation and experimental validation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YJMCC.2015.10.006

The power of two-dimensional dwell-time analysis for model discrimination, temporal resolution, multichannel analysis and level detection.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YJMCC.2015.10.006

Impact of KCNE subunits on KCNQ1 (Kv7.1) channel membrane surface targeting

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YJMCC.2015.10.006

Intracellular ATP binding is required to activate the slowly activating K channel I(Ks)

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YJMCC.2015.10.006

Atrial fibrillation in KCNE1-null mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YJMCC.2015.10.006

Activation and inactivation of homomeric KvLQT1 potassium channels.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YJMCC.2015.10.006

Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YJMCC.2015.10.006

Membrane-anchored aspartyl protease with Alzheimer's disease beta-secretase activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YJMCC.2015.10.006

Systematic proteomic analysis identifies β-site amyloid precursor protein cleaving enzyme 2 and 1 (BACE2 and BACE1) substrates in pancreatic β-cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YJMCC.2015.10.006

Voltage-gated K channel KCNQ1 regulates insulin secretion in MIN6 β-cell line.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YJMCC.2015.10.006

KCNQ1 long QT syndrome patients have hyperinsulinemia and symptomatic hypoglycemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YJMCC.2015.10.006

Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YJMCC.2015.10.006

SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YJMCC.2015.10.006

High activities of BACE1 in brains with mild cognitive impairment

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YJMCC.2015.10.006

Increased expression of the amyloid precursor beta-secretase in Alzheimer's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YJMCC.2015.10.006

Beta-secretase protein and activity are increased in the neocortex in Alzheimer disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YJMCC.2015.10.006

10.1016/J.YJMCC.2015.10.006

7 January 2021

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26454161 AND SRC:MED&resulttype=core&format=json

26 February 2020

1 reference