Milk Fat Globule-Epidermal Growth Factor 8 (MFG-E8) Is a Novel Anti-inflammatory Factor in Rheumatoid Arthritis in Mice and Humans (Q86207257)

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24 February 2020

title

Milk Fat Globule-Epidermal Growth Factor 8 (MFG-E8) Is a Novel Anti-inflammatory Factor in Rheumatoid Arthritis in Mice and Humans (English)

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15

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Triantafyllos Chavakis

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object named as

Triantafyllos Chavakis

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11

Henry Völzke

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author name string

Elise Albus

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Kathrin Sinningen

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Maria Winzer

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Sylvia Thiele

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Ulrike Baschant

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Anke Hannemann

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Julia Fantana

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Anne-Kathrin Tausche

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Henri Wallaschofski

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Matthias Nauck

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Sylvia Grossklaus

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Mark C Udey

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Martina Rauner

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publication date

9 November 2015

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Journal of Bone and Mineral Research

24 February 2020

published in

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volume

31

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issue

3

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page(s)

596-605

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Maturation-induced down-regulation of MFG-E8 impairs apoptotic cell clearance and enhances endotoxin response

24 February 2020

cites work

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12 December 2020

Organ-specific disease provoked by systemic autoimmunity

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12 December 2020

MFG-E8/Lactadherin Promotes Tumor Growth in an Angiogenesis-Dependent Transgenic Mouse Model of Multistage Carcinogenesis

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12 December 2020

Effects of the selective glucocorticoid receptor modulator compound A on bone metabolism and inflammation in male mice with collagen-induced arthritis

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12 December 2020

A second tumor necrosis factor receptor gene product can shed a naturally occurring tumor necrosis factor inhibitor

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12 December 2020

Potentiation of platelet-derived growth factor receptor-β signaling mediated by integrin-associated MFG-E8

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12 December 2020

Milk fat globule epidermal growth factor-factor 8 mitigates inflammation and tissue injury after hemorrhagic shock in experimental animals

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12 December 2020

Regulation of osteoclast homeostasis and inflammatory bone loss by MFG-E8.

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12 December 2020

The role of interleukin 6 in the pathophysiology of rheumatoid arthritis

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12 December 2020

Molecular Mechanisms Underlying the Regulation of the MFG-E8 Gene Promoter Activity in Physiological and Inflammatory Conditions

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12 December 2020

The roles of a novel anti-inflammatory factor, milk fat globule-epidermal growth factor 8, in patients with coronary atherosclerotic heart disease

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12 December 2020

Fractalkine-induced MFG-E8 leads to enhanced apoptotic cell clearance by macrophages

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12 December 2020

Identification of a factor that links apoptotic cells to phagocytes

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12 December 2020

Autoimmune disease and impaired uptake of apoptotic cells in MFG-E8-deficient mice

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12 December 2020

MFG-E8 attenuates intestinal inflammation in murine experimental colitis by modulating osteopontin-dependent alphavbeta3 integrin signaling.

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12 December 2020

The K/BxN arthritis model

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12 December 2020

Cohort Profile: The Study of Health in Pomerania

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12 December 2020

Polarization of prostate cancer-associated macrophages is induced by milk fat globule-EGF factor 8 (MFG-E8)-mediated efferocytosis

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12 December 2020

MFG-E8 released by apoptotic endothelial cells triggers anti-inflammatory macrophage reprogramming

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12 December 2020

Milk fat globule-EGF factor VIII in sepsis and ischemia-reperfusion injury

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12 December 2020

cDNA cloning of a mouse mammary epithelial cell surface protein reveals the existence of epidermal growth factor-like domains linked to factor VIII-like sequences

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12 December 2020

Milk Fat Globule-Epidermal Growth Factor-Factor 8 Attenuates Neutrophil Infiltration in Acute Lung Injury via Modulation of CXCR2

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12 December 2020

Milk fat globule–EGF factor VIII ameliorates liver injury after hepatic ischemia-reperfusion

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12 December 2020

Pre-treatment of recombinant mouse MFG-E8 downregulates LPS-induced TNF-α production in macrophages via STAT3-mediated SOCS3 activation

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12 December 2020

Dendritic cell-derived exosomes containing milk fat globule epidermal growth factor-factor VIII attenuate proinflammatory responses in sepsis.

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12 December 2020

Identification of genes differentially expressed in cultured human osteoblasts versus human fibroblasts by DNA microarray analysis

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12 December 2020

Review: milk fat globule-EGF factor 8 expression, function and plausible signal transduction in resolving inflammation

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12 December 2020

Selective glucocorticoid receptor modulation maintains bone mineral density in mice

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12 December 2020

Moonlighting osteoclasts as undertakers of apoptotic cells

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12 December 2020

Loss of milk fat globule-epidermal growth factor 8 (MFG-E8) in mice leads to low bone mass and accelerates ovariectomy-associated bone loss by increasing osteoclastogenesis.

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12 December 2020

Regulation of cytokines, cytokine inhibitors, and acute-phase proteins following anti-TNF-alpha therapy in rheumatoid arthritis

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12 December 2020

Milk fat globule epidermal growth factor 8 attenuates acute lung injury in mice after intestinal ischemia and reperfusion

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12 December 2020

Tumor necrosis factor α up-regulates endometrial milk fat globule-epidermal growth factor 8 protein production via nuclear factor κB activation, resulting in cell migration of epithelial cells

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12 December 2020

Milk Fat Globule-Epidermal Growth Factor 8 Is Decreased in Intestinal Epithelium of Ulcerative Colitis Patients and Thereby Causes Increased Apoptosis and Impaired Wound Healing

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12 December 2020

Milk fat globule epidermal growth factor 8 (MFG-E8) binds to oxidized phosphatidylserine: implications for macrophage clearance of apoptotic cells

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12 December 2020

Exogenous soluble tumor necrosis factor receptor type I ameliorates murine experimental autoimmune neuritis

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12 December 2020

MFG-E8 regulates angiogenesis in cutaneous wound healing

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12 December 2020

The role of neutrophils in autoimmune diseases.

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12 December 2020

Identifiers

DOI

10.1002/JBMR.2721

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24 February 2020

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24 February 2020

PubMed publication ID

26391522

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