Bittersweet memories: linking metabolism to epigenetics through O-GlcNAcylation (Q83951950)

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29 January 2020

title

Bittersweet memories: linking metabolism to epigenetics through O-GlcNAcylation (English)

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29 January 2020

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2

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29 January 2020

author name string

John A Hanover

series ordinal

1

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29 January 2020

Dona C Love

series ordinal

3

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29 January 2020

publication date

23 April 2012

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Nature Reviews Molecular Cell Biology

29 January 2020

published in

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volume

13

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issue

5

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29 January 2020

page(s)

312-321

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The significance, development and progress of high-throughput combinatorial histone code analysis

29 January 2020

cites work

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O-GlcNAc transferase catalyzes site-specific proteolysis of HCF-1

31 March 2020

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Crosstalk between O-GlcNAcylation and proteolytic cleavage regulates the host cell factor-1 maturation pathway

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GlcNAcylation of histone H2B facilitates its monoubiquitination

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Dynamic glycosylation of nuclear and cytosolic proteins. Cloning and characterization of a unique O-GlcNAc transferase with multiple tetratricopeptide repeats

31 March 2020

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Regulation of a cytosolic and nuclear O-GlcNAc transferase. Role of the tetratricopeptide repeats

31 March 2020

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Functional expression of O-linked GlcNAc transferase. Domain structure and substrate specificity

31 March 2020

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Mitochondrial and nucleocytoplasmic isoforms of O-linked GlcNAc transferase encoded by a single mammalian gene

31 March 2020

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Mitochondrial and nucleocytoplasmic targeting of O-linked GlcNAc transferase

31 March 2020

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Elevated O-GlcNAc-dependent signaling through inducible mOGT expression selectively triggers apoptosis

31 March 2020

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The superhelical TPR-repeat domain of O-linked GlcNAc transferase exhibits structural similarities to importin alpha

31 March 2020

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Structure of human O-GlcNAc transferase and its complex with a peptide substrate

31 March 2020

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Intron delays and transcriptional timing during development

31 March 2020

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The exon junction complex controls the splicing of MAPK and other long intron-containing transcripts in Drosophila

31 March 2020

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Denitrosylation of S-nitrosylated OGT is triggered in LPS-stimulated innate immune response

31 March 2020

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Dynamic O-glycosylation of nuclear and cytosolic proteins: cloning and characterization of a neutral, cytosolic beta-N-acetylglucosaminidase from human brain

31 March 2020

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The hexosamine signaling pathway: O-GlcNAc cycling in feast or famine

31 March 2020

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A lipid-droplet-targeted O-GlcNAcase isoform is a key regulator of the proteasome

31 March 2020

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Mechanism, Structure, and Inhibition of O-GlcNAc Processing Enzymes

31 March 2020

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Structural insights into the mechanism and inhibition of eukaryotic O-GlcNAc hydrolysis

31 March 2020

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Human OGA binds substrates in a conserved peptide recognition groove

31 March 2020

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Chemical arsenal for the study of O-GlcNAc.

31 March 2020

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Identification of a nuclear variant of MGEA5, a cytoplasmic hyaluronidase and a beta-N-acetylglucosaminidase

31 March 2020

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A Caenorhabditis elegans model of insulin resistance: altered macronutrient storage and dauer formation in an OGT-1 knockout

31 March 2020

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Caenorhabditis elegans ortholog of a diabetes susceptibility locus: oga-1 (O-GlcNAcase) knockout impacts O-GlcNAc cycling, metabolism, and dauer

31 March 2020

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O-linked-N-acetylglucosamine cycling and insulin signaling are required for the glucose stress response in Caenorhabditis elegans

31 March 2020

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Intracellular protein glycosylation modulates insulin mediated lifespan in C.elegans

31 March 2020

1 reference

A gene that regulates the bithorax complex differentially in larval and adult cells of Drosophila

31 March 2020

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The O-GlcNAc transferase gene resides on the X chromosome and is essential for embryonic stem cell viability and mouse ontogeny

31 March 2020

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Ogt-dependent X-chromosome-linked protein glycosylation is a requisite modification in somatic cell function and embryo viability

31 March 2020

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Identification of protein O-GlcNAcylation sites using electron transfer dissociation mass spectrometry on native peptides

31 March 2020

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Inactivation of phosphorylated endothelial nitric oxide synthase (Ser-1177) by O-GlcNAc in diabetes-associated erectile dysfunction

31 March 2020

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Hepatic glucose sensing via the CREB coactivator CRTC2.

31 March 2020

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Dynamic O-GlcNAc modification regulates CREB-mediated gene expression and memory formation

31 March 2020

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O-GlcNAc transferase is involved in glucocorticoid receptor-mediated transrepression

31 March 2020

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Control of alpha-herpesvirus IE gene expression by HCF-1 coupled chromatin modification activities

31 March 2020

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A single-point mutation in HCF causes temperature-sensitive cell-cycle arrest and disrupts VP16 function.

31 March 2020

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A versatile sugar transferase makes the cut

31 March 2020

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Human Sin3 deacetylase and trithorax-related Set1/Ash2 histone H3-K4 methyltransferase are tethered together selectively by the cell-proliferation factor HCF-1

31 March 2020

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Recruitment of O-GlcNAc transferase to promoters by corepressor mSin3A: coupling protein O-GlcNAcylation to transcriptional repression

31 March 2020

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O-GlcNAc transferase regulates mitotic chromatin dynamics

31 March 2020

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Polycomb repressive complex 2 is necessary for the normal site-specific O-GlcNAc distribution in mouse embryonic stem cells

31 March 2020

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β-N-Acetylglucosamine (O-GlcNAc) is a novel regulator of mitosis-specific phosphorylations on histone H3

31 March 2020

1 reference

A cellular memory module conveys epigenetic inheritance of hedgehog expression during Drosophila wing imaginal disc development

31 March 2020

1 reference

Maternal expression of genes that regulate the bithorax complex of Drosophila melanogaster.

31 March 2020

1 reference

Genetic interactions and dosage effects of Polycomb group genes of Drosophila.

31 March 2020

1 reference

Glucose-induced expression of MIP-1 genes requires O-GlcNAc transferase in monocytes

31 March 2020

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GlcNAcylation of a histone methyltransferase in retinoic-acid-induced granulopoiesis

31 March 2020

1 reference

A histone H3 lysine 36 trimethyltransferase links Nkx2-5 to Wolf-Hirschhorn syndrome

31 March 2020

1 reference

O-linked beta-N-acetylglucosaminyltransferase substrate specificity is regulated by myosin phosphatase targeting and other interacting proteins.

31 March 2020

1 reference

Ronin is essential for embryogenesis and the pluripotency of mouse embryonic stem cells

31 March 2020

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Ronin/Hcf-1 binds to a hyperconserved enhancer element and regulates genes involved in the growth of embryonic stem cells

31 March 2020

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31 March 2020

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An expanded Oct4 interaction network: implications for stem cell biology, development, and disease

31 March 2020

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An Oct4-centered protein interaction network in embryonic stem cells

31 March 2020

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Core transcriptional regulatory circuitry in human embryonic stem cells

31 March 2020

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Control of developmental regulators by Polycomb in human embryonic stem cells

31 March 2020

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Excessive O-GlcNAcylation of proteins suppresses spontaneous cardiogenesis in ES cells

31 March 2020

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Evolutionary diversity and developmental regulation of X-chromosome inactivation

31 March 2020

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Dosage compensation in the mouse balances up-regulation and silencing of X-linked genes

31 March 2020

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The pluripotency factor Oct4 interacts with Ctcf and also controls X-chromosome pairing and counting

31 March 2020

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Imprinted X inactivation maintained by a mouse Polycomb group gene

31 March 2020

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Epigenetic regulation of cellular memory by the Polycomb and Trithorax group proteins

31 March 2020

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Genome regulation by polycomb and trithorax proteins

31 March 2020

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Polycomb/Trithorax response elements and epigenetic memory of cell identity

31 March 2020

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Molecular links between X-inactivation and autosomal imprinting: X-inactivation as a driving force for the evolution of imprinting?

31 March 2020

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Canalization of Development and Genetic Assimilation of Acquired Characters

31 March 2020

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Type 2 (non-insulin-dependent) diabetes mellitus: the thrifty phenotype hypothesis

31 March 2020

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The thrifty phenotype hypothesis

31 March 2020

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Altered glycan-dependent signaling induces insulin resistance and hyperleptinemia

31 March 2020

1 reference

Elevated nucleocytoplasmic glycosylation by O-GlcNAc results in insulin resistance associated with defects in Akt activation in 3T3-L1 adipocytes

31 March 2020

1 reference

Blocking O-Linked GlcNAc Cycling in Drosophila Insulin-producing Cells Perturbs Glucose-Insulin Homeostasis

31 March 2020

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Phosphoinositide signalling links O-GlcNAc transferase to insulin resistance

31 March 2020

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MGEA5-14 polymorphism and type 2 diabetes in Mexico City

31 March 2020

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A single nucleotide polymorphism in MGEA5 encoding O-GlcNAc-selective N-acetyl-beta-D glucosaminidase is associated with type 2 diabetes in Mexican Americans

31 March 2020

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The vicious cycle of diabetes and pregnancy

31 March 2020

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A potent mechanism-inspired O-GlcNAcase inhibitor that blocks phosphorylation of tau in vivo

31 March 2020

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O-GlcNAc modification in diabetes and Alzheimer's disease

31 March 2020

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O-GlcNAc cycling: implications for neurodegenerative disorders

31 March 2020

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O-GlcNAc regulates FoxO activation in response to glucose

31 March 2020

1 reference

c-Myc Is Glycosylated at Threonine 58, a Known Phosphorylation Site and a Mutational Hot Spot in Lymphomas

31 March 2020

1 reference

The coactivator of transcription CREB-binding protein interacts preferentially with the glycosylated form of Stat5.

31 March 2020

1 reference

Regulation of CK2 by phosphorylation and O-GlcNAcylation revealed by semisynthesis

31 March 2020

1 reference

Mad-Max transcriptional repression is mediated by ternary complex formation with mammalian homologs of yeast repressor Sin3

31 March 2020

1 reference

Transmembrane assembly of N-linked glycoproteins. Studies on the topology of saccharide synthesis

31 March 2020

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12 December 2020

Coordinated regulation of glutamine:fructose-6-phosphate amidotransferase activity by insulin, glucose, and glutamine. Role of hexosamine biosynthesis in enzyme regulation

1 reference

12 December 2020

The subcellular distribution of terminal N-acetylglucosamine moieties. Localization of a novel protein-saccharide linkage, O-linked GlcNAc.

1 reference

12 December 2020

A screen for new trithorax group genes identified little imaginal discs, the Drosophila melanogaster homologue of human retinoblastoma binding protein 2.

1 reference

12 December 2020

O-linked N-acetylglucosamine is attached to proteins of the nuclear pore. Evidence for cytoplasmic and nucleoplasmic glycoproteins

1 reference

12 December 2020

The hexosamine signaling pathway: deciphering the "O-GlcNAc code"

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12 December 2020

Diabetes mellitus: a "thrifty" genotype rendered detrimental by "progress"?

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12 December 2020

Discovery of a metabolic pathway mediating glucose-induced desensitization of the glucose transport system. Role of hexosamine biosynthesis in the induction of insulin resistance

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12 December 2020

Interactions of polyhomeotic with Polycomb group genes of Drosophila melanogaster.

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12 December 2020