Delayed-onset caspase-dependent massive hepatocyte apoptosis upon Fas activation in Bak/Bax-deficient mice (Q83677023)

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26 January 2020

title

Delayed-onset caspase-dependent massive hepatocyte apoptosis upon Fas activation in Bak/Bax-deficient mice (English)

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3

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author name string

Hayato Hikita

1

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26 January 2020

Tetsuo Takehara

2

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26 January 2020

Satoshi Shimizu

4

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26 January 2020

Minoru Shigekawa

5

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26 January 2020

Atsushi Hosui

6

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Takuya Miyagi

7

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Tomohide Tatsumi

8

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Hisashi Ishida

9

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Wei Li

10

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Tatsuya Kanto

11

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Naoki Hiramatsu

12

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Shigeomi Shimizu

13

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Yoshihide Tsujimoto

14

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Norio Hayashi

15

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language of work or name

English

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publication date

11 April 2011

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26 January 2020

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volume

54

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issue

1

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page(s)

240-251

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Life and death by death receptors

26 January 2020

cites work

1 reference

7 January 2021

Hepatocyte Death: A Clear and Present Danger

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7 January 2021

Involvement of Fas system-mediated apoptosis in pathogenesis of viral hepatitis

1 reference

7 January 2021

Hepatocyte apoptosis and fas expression are prominent features of human nonalcoholic steatohepatitis

1 reference

7 January 2021

Significance of Fas antigen-mediated apoptosis in human fulminant hepatic failure

1 reference

7 January 2021

Fas-mediated apoptosis of hepatic cells

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7 January 2021

Cell death regulation by the Bcl-2 protein family in the mitochondria

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7 January 2021

Mitochondria and cell death: outer membrane permeabilization and beyond

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7 January 2021

Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis

1 reference

7 January 2021

The BH3-Only Protein Bid Is Dispensable for DNA Damage- and Replicative Stress-Induced Apoptosis or Cell-Cycle Arrest

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7 January 2021

The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues

1 reference

7 January 2021

Hepatocyte-specific disruption of Bcl-xL leads to continuous hepatocyte apoptosis and liver fibrotic responses.

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7 January 2021

Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death

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7 January 2021

Mcl-1 and Bcl-xL cooperatively maintain integrity of hepatocytes in developing and adult murine liver

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7 January 2021

BH3-only protein bid participates in the Bcl-2 network in healthy liver cells

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7 January 2021

BID: a novel BH3 domain-only death agonist

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7 January 2021

Requirement of voltage-dependent anion channel 2 for pro-apoptotic activity of Bax.

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7 January 2021

Lethal effect of the anti-Fas antibody in mice

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7 January 2021

Activation of caspase-8 in drug-induced apoptosis of B-lymphoid cells is independent of CD95/Fas receptor-ligand interaction and occurs downstream of caspase-3.

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7 January 2021

Bax is present as a high molecular weight oligomer/complex in the mitochondrial membrane of apoptotic cells

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7 January 2021

Bid-induced cytochrome c release is mediated by a pathway independent of mitochondrial permeability transition pore and Bax.

1 reference

7 January 2021

The strength of the Fas ligand signal determines whether hepatocytes act as type 1 or type 2 cells in murine livers

1 reference

7 January 2021

Activation of Fas by FasL induces apoptosis by a mechanism that cannot be blocked by Bcl-2 or Bcl-x(L)

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7 January 2021

Caspase-9 processing by caspase-3 via a feedback amplification loop in vivo

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7 January 2021

IAP family proteins--suppressors of apoptosis

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7 January 2021

XIAP discriminates between type I and type II FAS-induced apoptosis

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7 January 2021

Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule

1 reference

7 January 2021

Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury

1 reference

7 January 2021

Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death

1 reference

7 January 2021

Q-VD-OPh, a broad spectrum caspase inhibitor with potent antiapoptotic properties

1 reference

7 January 2021

Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

1 reference

7 January 2021

Switch from type II to I Fas/CD95 death signaling on in vitro culturing of primary hepatocytes

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7 January 2021

Tumor necrosis factor α sensitizes primary murine hepatocytes to Fas/CD95-induced apoptosis in a Bim- and Bid-dependent manner

1 reference

7 January 2021

Fas (CD95, APO-1) antigen expression and function in murine liver endothelial cells: implications for the regulation of apoptosis in liver endothelial cells.

1 reference

7 January 2021

Clinical Trial of the Pan-Caspase Inhibitor, IDN-6556, in Human Liver Preservation Injury

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7 January 2021

Oral IDN-6556, an antiapoptotic caspase inhibitor, may lower aminotransferase activity in patients with chronic hepatitis C.

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7 January 2021

Identifiers

DOI

10.1002/HEP.24305

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26 January 2020

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