One novel quinoxaline derivative as a potent human cyclophilin A inhibitor shows highly inhibitory activity against mouse spleen cell proliferation (Q83304248)

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scientific article published on 06 May 2006

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English	One novel quinoxaline derivative as a potent human cyclophilin A inhibitor shows highly inhibitory activity against mouse spleen cell proliferation	scientific article published on 06 May 2006

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20 January 2020

One novel quinoxaline derivative as a potent human cyclophilin A inhibitor shows highly inhibitory activity against mouse spleen cell proliferation (English)

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20 January 2020

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Xu Shen

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20 January 2020

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Jian Li

1

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20 January 2020

Jing Chen

2

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20 January 2020

Li Zhang

3

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20 January 2020

Feng Wang

4

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20 January 2020

Chunshan Gui

5

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20 January 2020

Li Zhang

6

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20 January 2020

Yu Qin

7

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20 January 2020

Qiang Xu

8

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20 January 2020

Hong Liu

9

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20 January 2020

Fajun Nan

10

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20 January 2020

Jingkang Shen

11

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20 January 2020

Donglu Bai

12

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20 January 2020

Kaixian Chen

13

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20 January 2020

Hualiang Jiang

15

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20 January 2020

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publication date

6 May 2006

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20 January 2020

Bioorganic & Medicinal Chemistry

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20 January 2020

14

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20 January 2020

16

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20 January 2020

5527-5534

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20 January 2020

Synthesis of stereoisomers of antithrombotic nipecotamides

1 reference

https://pubmed.ncbi.nlm.nih.gov/16682211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Determination of kinetic constants for peptidyl prolyl cis-trans isomerases by an improved spectrophotometric assay

1 reference

https://pubmed.ncbi.nlm.nih.gov/16682211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mode of action of SDZ NIM 811, a nonimmunosuppressive cyclosporin A analog with activity against human immunodeficiency virus (HIV) type 1: interference with HIV protein-cyclophilin A interactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/16682211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sanglifehrin-cyclophilin interaction: degradation work, synthetic macrocyclic analogues, X-ray crystal structure, and binding data

1 reference

https://pubmed.ncbi.nlm.nih.gov/16682211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclophilin and gag in HIV-1 replication and pathogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16682211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The T-cell transcription factor NFATp is a substrate for calcineurin and interacts with Fos and Jun

1 reference

https://pubmed.ncbi.nlm.nih.gov/16682211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nucleocapsid protein of SARS coronavirus tightly binds to human cyclophilin A.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16682211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Appraisal of the MTT assay as a rapid test of chemosensitivity in acute myeloid leukaemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/16682211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclophilin: a specific cytosolic binding protein for cyclosporin A

1 reference

https://pubmed.ncbi.nlm.nih.gov/16682211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloning, expression, and purification of human cyclophilin in Escherichia coli and assessment of the catalytic role of cysteines by site-directed mutagenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16682211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional association of cyclophilin A with HIV-1 virions

1 reference

https://pubmed.ncbi.nlm.nih.gov/16682211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuronal localization of the cyclophilin A protein in the adult rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/16682211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peptidyl prolyl cis-trans isomerase activity of cyclophilin A in functional homo-oligomeric receptor expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/16682211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isocyanate as a Versatile Synthon for Modular Synthesis of Functionalized Porphyrins

1 reference

https://pubmed.ncbi.nlm.nih.gov/16682211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specific incorporation of cyclophilin A into HIV-1 virions

1 reference

https://pubmed.ncbi.nlm.nih.gov/16682211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assembly and morphology of HIV: potential effect of structure on viral function

1 reference

https://pubmed.ncbi.nlm.nih.gov/16682211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Active-site residues of cyclophilin A are crucial for its incorporation into human immunodeficiency virus type 1 virions

1 reference

https://pubmed.ncbi.nlm.nih.gov/16682211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis and localization of cyclophilin A found in the virions of human immunodeficiency virus type 1 MN strain

1 reference

https://pubmed.ncbi.nlm.nih.gov/16682211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclosporin A regulates the levels of cyclophilin A in neuroblastoma cells in culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/16682211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclosporine (Sandimmun) in cadaveric renal transplantation. Ten-year follow-up of a multicenter trial. European Multicentre Trial Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/16682211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human and Escherichia coli cyclophilins: sensitivity to inhibition by the immunosuppressant cyclosporin A correlates with a specific tryptophan residue.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16682211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kinetic beta-deuterium isotope effects suggest a covalent mechanism for the protein folding enzyme peptidylprolyl cis/trans-isomerase

1 reference

https://pubmed.ncbi.nlm.nih.gov/16682211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure of human cyclophilin and its binding site for cyclosporin A determined by X-ray crystallography and NMR spectroscopy

1 reference

https://pubmed.ncbi.nlm.nih.gov/16682211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An all atom force field for simulations of proteins and nucleic acids

1 reference

https://pubmed.ncbi.nlm.nih.gov/16682211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16682211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclophilin and peptidyl-prolyl cis-trans isomerase are probably identical proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/16682211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclophilin A is required for the replication of group M human immunodeficiency virus type 1 (HIV-1) and simian immunodeficiency virus SIV(CPZ)GAB but not group O HIV-1 or other primate immunodeficiency viruses

1 reference

https://pubmed.ncbi.nlm.nih.gov/16682211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HIV-1 gag proteins: diverse functions in the virus life cycle

1 reference

https://pubmed.ncbi.nlm.nih.gov/16682211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparative binding studies of cyclophilins to cyclosporin A and derivatives by fluorescence measurements

1 reference

https://pubmed.ncbi.nlm.nih.gov/16682211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human immunodeficiency virus type 1 Gag protein binds to cyclophilins A and B

1 reference

https://pubmed.ncbi.nlm.nih.gov/16682211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The hydrophobic pocket of cyclophilin is the binding site for the human immunodeficiency virus type 1 Gag polyprotein

1 reference

https://pubmed.ncbi.nlm.nih.gov/16682211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation of the cyclosporin-sensitive T cell transcription factor NFATp

1 reference

https://pubmed.ncbi.nlm.nih.gov/16682211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

X-ray structure of a decameric cyclophilin-cyclosporin crystal complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/16682211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peptidyl-prolyl cis-trans isomerase is the cyclosporin A-binding protein cyclophilin

1 reference

https://pubmed.ncbi.nlm.nih.gov/16682211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclophilin A regulates HIV-1 infectivity, as demonstrated by gene targeting in human T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16682211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mode of action of SDZ NIM 811, a nonimmunosuppressive cyclosporin A analog with activity against human immunodeficiency virus type 1 (HIV-1): interference with early and late events in HIV-1 replication

1 reference

https://pubmed.ncbi.nlm.nih.gov/16682211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Form, function, and use of retroviral gag proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/16682211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcineurin binds the transcription factor NFAT1 and reversibly regulates its activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/16682211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.BMC.2006.04.026

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16682211 AND SRC:MED&resulttype=core&format=json

20 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16682211 AND SRC:MED&resulttype=core&format=json

20 January 2020

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