Local pulmonary immunotherapy with siRNA targeting TGFβ1 enhances antimicrobial capacity in Mycobacterium tuberculosis infected mice (Q83080136)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21195670 AND SRC:MED&resulttype=core&format=json

19 January 2020

title

Local pulmonary immunotherapy with siRNA targeting TGFβ1 enhances antimicrobial capacity in Mycobacterium tuberculosis infected mice (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21195670 AND SRC:MED&resulttype=core&format=json

Mycobacterium tuberculosis

19 January 2020

main subject

1 reference

1 reference

Adrian G Rosas-Taraco

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21195670 AND SRC:MED&resulttype=core&format=json

19 January 2020

David M Higgins

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21195670 AND SRC:MED&resulttype=core&format=json

19 January 2020

Joaquín Sánchez-Campillo

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21195670 AND SRC:MED&resulttype=core&format=json

19 January 2020

Eric J Lee

4

1 reference

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19 January 2020

publication date

31 December 2010

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19 January 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21195670 AND SRC:MED&resulttype=core&format=json

19 January 2020

volume

91

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19 January 2020

issue

1

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19 January 2020

page(s)

98-106

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Multidrug-resistant and extensively drug-resistant tuberculosis: implications for the HIV epidemic and antiretroviral therapy rollout in South Africa

19 January 2020

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Suppression of discoidin domain receptor 1 by RNA interference attenuates lung inflammation

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Circulating TNF-alpha, TGF-beta, and IL-10 in tuberculosis patients and healthy contacts

7 January 2021

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7 January 2021

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In vivo IL-10 production reactivates chronic pulmonary tuberculosis in C57BL/6 mice.

7 January 2021

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Down-modulation of lung immune responses by interleukin-10 and transforming growth factor beta (TGF-beta) and analysis of TGF-beta receptors I and II in active tuberculosis.

7 January 2021

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7 January 2021

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TGF-beta 1 suppresses [correction of supresses] myeloid Fc gamma receptor function by regulating the expression and function of the common gamma-subunit.

7 January 2021

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TGF-beta1 suppresses IFN-gamma-induced NO production in macrophages by suppressing STAT1 activation and accelerating iNOS protein degradation.

7 January 2021

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7 January 2021

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Transforming growth factor-beta decreases survival of Mycobacterium bovis-activated T cells

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7 January 2021

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Tumor necrosis factor blockade in chronic murine tuberculosis enhances granulomatous inflammation and disorganizes granulomas in the lungs

7 January 2021

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Different modes of IL-10 and TGF-beta to inhibit cytokine-dependent IFN-gamma production: consequences for reversal of lipopolysaccharide desensitization

7 January 2021

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Nitric oxide and macrophage function

7 January 2021

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Transforming growth factor (TGF)-beta1-producing regulatory T cells induce Smad-mediated interleukin 10 secretion that facilitates coordinated immunoregulatory activity and amelioration of TGF-beta1-mediated fibrosis

7 January 2021

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A combination of a transforming growth factor-beta antagonist and an inhibitor of cyclooxygenase is an effective treatment for murine pulmonary tuberculosis

7 January 2021

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7 January 2021

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7 January 2021

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Relative levels of M-CSF and GM-CSF influence the specific generation of macrophage populations during infection with Mycobacterium tuberculosis

7 January 2021

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Complete chromogen separation and analysis in double immunohistochemical stains using Photoshop-based image analysis

7 January 2021

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RNAi-based drug discovery and its application to therapeutics

7 January 2021

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21195670

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages. Comparison of activating cytokines and evidence for independent production

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21195670

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

siRNAs in drug discovery: target validation and beyond

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21195670

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.TUBE.2010.11.004

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21195670 AND SRC:MED&resulttype=core&format=json

19 January 2020

1 reference