Combined positivity for HLA DQ2/DQ8 and IA-2 antibodies defines population at high risk of developing type 1 diabetes (Q81499458)

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9 January 2020

title

Combined positivity for HLA DQ2/DQ8 and IA-2 antibodies defines population at high risk of developing type 1 diabetes (English)

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K Decochez

1

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I Truyen

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B van der Auwera

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I Weets

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E Vandemeulebroucke

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I H de Leeuw

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C Mathieu

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R Rottiers

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D G Pipeleers

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F K Gorus

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Belgian Diabetes Registry

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9 January 2020

publication date

9 March 2005

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9 January 2020

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volume

48

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issue

4

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9 January 2020

page(s)

687-694

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Influence of age on the associations among insulin autoantibodies, islet cell antibodies, and HLA DAQ1*0301-DQB1*0302 in siblings of patients with type 1 (insulin-dependent) diabetes mellitus. Belgian Diabetes Registry

9 January 2020

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IA-2-autoantibodies complement GAD65-autoantibodies in new-onset IDDM patients and help predict impending diabetes in their siblings. The Belgian Diabetes Registry

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Only multiple autoantibodies to islet cells (ICA), insulin, GAD65, IA-2 and IA-2beta predict immune-mediated (Type 1) diabetes in relatives

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Associations of GAD65- and IA-2-Autoantibodies With Genetic Risk Markers in New-Onset IDDM Patients and Their Siblings. The Belgian Diabetes Registry

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Genetic susceptibility for insulin-dependent diabetes mellitus in Caucasians revisited: the importance of diabetes registries in disclosing interactions between HLA-DQ- and insulin gene-linked risk. Belgian Diabetes Registry

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IA-2 autoantibodies predict impending type I diabetes in siblings of patients

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First-degree relatives of patients with type I diabetes mellitus. Islet-cell antibodies and abnormal insulin secretion

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12 December 2020

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European Nicotinamide Diabetes Intervention Trial (ENDIT): a randomised controlled trial of intervention before the onset of type 1 diabetes

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Transient antiislet autoantibodies: infrequent occurrence and lack of association with "genetic" risk factors

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Antiislet autoantibodies usually develop sequentially rather than simultaneously

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High frequency of persisting or increasing islet-specific autoantibody levels after diagnosis of type 1 diabetes presenting before 40 years of age. The Belgian Diabetes Registry

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Genetic effects on age-dependent onset and islet cell autoantibody markers in type 1 diabetes

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12 December 2020

Genetic risk determines the emergence of diabetes-associated autoantibodies in young children

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12 December 2020

Evaluation of survival data and two new rank order statistics arising in its consideration

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12 December 2020

Prediction of insulin-dependent diabetes mellitus in siblings of children with diabetes. A population-based study. The Childhood Diabetes in Finland Study Group

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12 December 2020

Multiple significance tests: the Bonferroni method

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12 December 2020

Male-to-female excess in diabetes diagnosed in early adulthood is not specific for the immune-mediated form nor is it HLA-DQ restricted: possible relation to increased body mass index.

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12 December 2020

Autoantigens IA-2 and GAD in Type I (insulin-dependent) diabetes

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12 December 2020

HLA-DR 3 is associated with a more slowly progressive form of Type 1 (insulin-dependent) diabetes

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12 December 2020

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12 December 2020

Differences in risk of insulin-dependent diabetes in offspring of diabetic mothers and diabetic fathers

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12 December 2020

Prospects for predicting and stopping the development of type 1 of diabetes

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12 December 2020

Combined analysis of autoantibodies improves prediction of IDDM in islet cell antibody-positive relatives

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12 December 2020