Negative regulation of cytokine signaling (Q81133805)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16129905 AND SRC:MED&resulttype=core&format=json

6 January 2020

review article

1 reference

title

Negative regulation of cytokine signaling (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16129905 AND SRC:MED&resulttype=core&format=json

6 January 2020

author name string

Akihiko Yoshimura

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16129905 AND SRC:MED&resulttype=core&format=json

6 January 2020

publication date

1 June 2005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16129905 AND SRC:MED&resulttype=core&format=json

Clinical Reviews in Allergy & Immunology

6 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16129905 AND SRC:MED&resulttype=core&format=json

6 January 2020

volume

28

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16129905 AND SRC:MED&resulttype=core&format=json

6 January 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16129905 AND SRC:MED&resulttype=core&format=json

6 January 2020

page(s)

205-220

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16129905 AND SRC:MED&resulttype=core&format=json

Combined hypermethylation and chromosome loss associated with inactivation of SSI-1/SOCS-1/JAB gene in human hepatocellular carcinomas

6 January 2020

cites work

1 reference

12 December 2020

SOCS3 is a critical physiological negative regulator of G-CSF signaling and emergency granulopoiesis

1 reference

12 December 2020

Severe defects in immunity and hematopoiesis caused by SHP-1 protein-tyrosine-phosphatase deficiency

1 reference

12 December 2020

Cytokine receptor signalling

1 reference

12 December 2020

PIAS1 selectively inhibits interferon-inducible genes and is important in innate immunity.

1 reference

12 December 2020

The Ras-Raf relationship: an unfinished puzzle

1 reference

12 December 2020

Cytokine signaling in 2002: new surprises in the Jak/Stat pathway

1 reference

12 December 2020

A novel cytokine-inducible gene CIS encodes an SH2-containing protein that binds to tyrosine-phosphorylated interleukin 3 and erythropoietin receptors

1 reference

12 December 2020

Induction of the cytokine signal regulator SOCS3/CIS3 as a therapeutic strategy for treating inflammatory arthritis

1 reference

12 December 2020

Epigenetic inactivation of SOCS-1 by CpG island hypermethylation in human gastric carcinoma

1 reference

12 December 2020

Suppressors of cytokine signaling and immunity

1 reference

12 December 2020

SOCS-1 participates in negative regulation of LPS responses

1 reference

12 December 2020

The protein tyrosine phosphatase SHP-2 negatively regulates ciliary neurotrophic factor induction of gene expression

1 reference

12 December 2020

SOCS3 is a physiological negative regulator for granulopoiesis and granulocyte colony-stimulating factor receptor signaling.

1 reference

12 December 2020

Negative regulation of cytokine signaling pathways

1 reference

12 December 2020

SOCS-1, a negative regulator of the JAK/STAT pathway, is silenced by methylation in human hepatocellular carcinoma and shows growth-suppression activity

1 reference

12 December 2020

Aberrant methylation of SOCS-1 was observed in younger colorectal cancer patients

1 reference

12 December 2020

A new high affinity binding site for suppressor of cytokine signaling-3 on the erythropoietin receptor

1 reference

12 December 2020

Resistance to IL-10 inhibition of interferon gamma production and expression of suppressor of cytokine signaling 1 in CD4 T cells from patients with rheumatoid arthritis

1 reference

12 December 2020

Placental defects and embryonic lethality in mice lacking suppressor of cytokine signaling 3

1 reference

12 December 2020

SOCS3: an essential regulator of LIF receptor signaling in trophoblast giant cell differentiation

1 reference

12 December 2020

The conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple bound proteins to proteasomal degradation

1 reference

12 December 2020

Hypermethylation-associated inactivation of the SOCS-1 gene, a JAK/STAT inhibitor, in human pancreatic cancers.

1 reference

12 December 2020

Spred-1 negatively regulates allergen-induced airway eosinophilia and hyperresponsiveness

1 reference

12 December 2020

VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligases

1 reference

12 December 2020

SOCS36E, a novel Drosophila SOCS protein, suppresses JAK/STAT and EGF-R signalling in the imaginal wing disc

1 reference

12 December 2020

Promoter hypermethylation of tumor-related genes in the progression of colorectal neoplasia.

1 reference

12 December 2020

Spred is a Sprouty-related suppressor of Ras signalling

1 reference

12 December 2020

Suppressors of cytokine signaling: Relevance to gastrointestinal function and disease

1 reference

12 December 2020

STAT3 is a negative regulator of granulopoiesis but is not required for G-CSF-dependent differentiation

1 reference

12 December 2020

SHP2 and SOCS3 contribute to Tyr-759-dependent attenuation of interleukin-6 signaling through gp130

1 reference

12 December 2020

Spred-2 suppresses aorta-gonad-mesonephros hematopoiesis by inhibiting MAP kinase activation

1 reference

12 December 2020

The JAK-binding protein JAB inhibits Janus tyrosine kinase activity through binding in the activation loop

1 reference

12 December 2020

SOCS1 deficiency causes a lymphocyte-dependent perinatal lethality

1 reference

12 December 2020

Suppressor of cytokine signalling-1 gene silencing in acute myeloid leukaemia and human haematopoietic cell lines

1 reference

12 December 2020

Aberrant promoter hypermethylation of multiple genes in gallbladder carcinoma and chronic cholecystitis

1 reference

12 December 2020

A SOCS-1 peptide mimetic inhibits both constitutive and IL-6 induced activation of STAT3 in prostate cancer cells.

1 reference

12 December 2020

Constitutive expression of SOCS3 confers resistance to IFN-alpha in chronic myelogenous leukemia cells

1 reference

12 December 2020

A three-dimensional model of Suppressor Of Cytokine Signalling 1 (SOCS-1).

1 reference

12 December 2020

Suppressor of cytokine signaling 1 (SOCS-1) and SOCS-3 cause insulin resistance through inhibition of tyrosine phosphorylation of insulin receptor substrate proteins by discrete mechanisms

1 reference

12 December 2020

Molecular cloning of mammalian Spred-3 which suppresses tyrosine kinase-mediated Erk activation

1 reference

12 December 2020

SOCS-1/SSI-1-deficient NKT cells participate in severe hepatitis through dysregulated cross-talk inhibition of IFN-gamma and IL-4 signaling in vivo

1 reference

12 December 2020

Constitutional activation of IL-6-mediated JAK/STAT pathway through hypermethylation of SOCS-1 in human gastric cancer cell line

1 reference

12 December 2020

Inhibitors of cytokine signal transduction

1 reference

12 December 2020

Polycystic kidneys and chronic inflammatory lesions are the delayed consequences of loss of the suppressor of cytokine signaling-1 (SOCS-1).

1 reference

12 December 2020

Growth enhancement in suppressor of cytokine signaling 2 (SOCS-2)-deficient mice is dependent on signal transducer and activator of transcription 5b (STAT5b)

1 reference

12 December 2020

Roles of the SHP-1 tyrosine phosphatase in the negative regulation of cell signalling

1 reference

12 December 2020

A point mutation of Tyr-759 in interleukin 6 family cytokine receptor subunit gp130 causes autoimmune arthritis

1 reference

12 December 2020

IL-6 induces an anti-inflammatory response in the absence of SOCS3 in macrophages

1 reference

12 December 2020

SOCS1/JAB is a negative regulator of LPS-induced macrophage activation

1 reference

12 December 2020

SOCS-3 regulates onset and maintenance of T(H)2-mediated allergic responses

1 reference

12 December 2020

Modulation of signalling by Sprouty: a developing story

1 reference

12 December 2020

Silencing of SOCS1 enhances antigen presentation by dendritic cells and antigen-specific anti-tumor immunity

1 reference

12 December 2020

Regulation of NF-kappaB signaling by Pin1-dependent prolyl isomerization and ubiquitin-mediated proteolysis of p65/RelA.

1 reference

12 December 2020

Suppressors of cytokine signalling (SOCS) in the immune system

1 reference

12 December 2020

Local activation of STAT-1 and STAT-3 in the inflamed synovium during zymosan-induced arthritis: exacerbation of joint inflammation in STAT-1 gene-knockout mice

1 reference

12 December 2020

SH2 domains from suppressor of cytokine signaling-3 and protein tyrosine phosphatase SHP-2 have similar binding specificities

1 reference

12 December 2020

The Elongin BC complex interacts with the conserved SOCS-box motif present in members of the SOCS, ras, WD-40 repeat, and ankyrin repeat families

1 reference

12 December 2020

Suppressor of cytokine signaling-1 regulates acute inflammatory arthritis and T cell activation

1 reference

12 December 2020

Socs3 deficiency in the brain elevates leptin sensitivity and confers resistance to diet-induced obesity

1 reference

12 December 2020

Suppressor of cytokine signaling-1 is a critical regulator of interleukin-7-dependent CD8 T cell differentiation.

1 reference

12 December 2020

Can SOCS make arthritis better?

1 reference

12 December 2020

Aberrant Promoter Methylation Profiles of Tumor Suppressor Genes in Hepatocellular Carcinoma

1 reference

12 December 2020

Differential hypermethylation of SOCS genes in ovarian and breast carcinomas.

1 reference

12 December 2020

Constitutive SOCS-3 expression protects T-cell lymphoma against growth inhibition by IFNalpha.

1 reference

12 December 2020

Enhanced Th1 activity and development of chronic enterocolitis in mice devoid of Stat3 in macrophages and neutrophils.

1 reference

12 December 2020

Indirect induction of suppressor of cytokine signalling-1 in macrophages stimulated with bacterial lipopolysaccharide: partial role of autocrine/paracrine interferon-alpha/beta

1 reference

12 December 2020

SOCS3 regulates the plasticity of gp130 signaling

1 reference

12 December 2020

Suppressors of cytokine signaling (SOCS)-1 and SOCS-3 are induced by CpG-DNA and modulate cytokine responses in APCs

1 reference

12 December 2020

Characterization of a peptide inhibitor of Janus kinase 2 that mimics suppressor of cytokine signaling 1 function

1 reference

12 December 2020

PIAS/SUMO: new partners in transcriptional regulation.

1 reference

12 December 2020

SOCS-6 binds to insulin receptor substrate 4, and mice lacking the SOCS-6 gene exhibit mild growth retardation

1 reference

12 December 2020

Dual signaling role of the protein tyrosine phosphatase SHP-2 in regulating expression of acute-phase plasma proteins by interleukin-6 cytokine receptors in hepatic cells.

1 reference

12 December 2020

Enhanced leptin sensitivity and attenuation of diet-induced obesity in mice with haploinsufficiency of Socs3.

1 reference

12 December 2020

Socs-1 inhibits TEL-JAK2-mediated transformation of hematopoietic cells through inhibition of JAK2 kinase activity and induction of proteasome-mediated degradation

1 reference

12 December 2020

Suppression of STAT5 functions in liver, mammary glands, and T cells in cytokine-inducible SH2-containing protein 1 transgenic mice

1 reference

12 December 2020

SOCS5 is expressed in primary B and T lymphoid cells but is dispensable for lymphocyte production and function

1 reference

12 December 2020

LPS and TNFalpha induce SOCS3 mRNA and inhibit IL-6-induced activation of STAT3 in macrophages.

1 reference

12 December 2020

Promoter CpG methylation of tumor suppressor genes in colorectal cancer and its relationship to clinical features.

1 reference

12 December 2020

DNA methylation changes in multiple myeloma

1 reference

12 December 2020

Reciprocal regulation of gastrointestinal homeostasis by SHP2 and STAT-mediated trefoil gene activation in gp130 mutant mice

1 reference

12 December 2020

Induction of hyper Th1 cell-type immune responses by dendritic cells lacking the suppressor of cytokine signaling-1 gene

1 reference

12 December 2020

CIS3/SOCS3/SSI3 plays a negative regulatory role in STAT3 activation and intestinal inflammation

1 reference

12 December 2020

The role of suppressors of cytokine signaling (SOCS) proteins in regulation of the immune response

1 reference

12 December 2020

Regulation of Jak2 through the ubiquitin-proteasome pathway involves phosphorylation of Jak2 on Y1007 and interaction with SOCS-1.

1 reference

12 December 2020

Protein inhibitor of activated STAT Y (PIASy) and a splice variant lacking exon 6 enhance sumoylation but are not essential for embryogenesis and adult life

1 reference

12 December 2020

SOCS1 is a critical inhibitor of interferon gamma signaling and prevents the potentially fatal neonatal actions of this cytokine.

1 reference

12 December 2020

Gigantism in mice lacking suppressor of cytokine signalling-2

1 reference

12 December 2020

Neutralization of interferon-gamma in neonatal SOCS1-/- mice prevents fatty degeneration of the liver but not subsequent fatal inflammatory disease

1 reference

12 December 2020

Suppressor of cytokine signaling-3 preferentially binds to the SHP-2-binding site on the shared cytokine receptor subunit gp130

1 reference

12 December 2020

The T cell protein tyrosine phosphatase is a negative regulator of janus family kinases 1 and 3

1 reference

12 December 2020

SOCS1 is a suppressor of liver fibrosis and hepatitis-induced carcinogenesis

1 reference

12 December 2020

Suppressor of Cytokine Signaling-1 Is Essential for Suppressing Dendritic Cell Activation and Systemic Autoimmunity

1 reference

12 December 2020

Regulation of JAK-STAT signalling in the immune system

1 reference

12 December 2020

SOCS3 negatively regulates IL-6 signaling in vivo

1 reference

12 December 2020

Biallelic mutation of SOCS-1 impairs JAK2 degradation and sustains phospho-JAK2 action in the MedB-1 mediastinal lymphoma line

1 reference

12 December 2020