Estimating the safe starting dose in phase I clinical trials and no observed effect level based on QSAR modeling of the human maximum recommended daily dose (Q81013987)

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scientific article published on 01 December 2004

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English	Estimating the safe starting dose in phase I clinical trials and no observed effect level based on QSAR modeling of the human maximum recommended daily dose	scientific article published on 01 December 2004

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15546675 AND SRC:MED&resulttype=core&format=json

5 January 2020

Estimating the safe starting dose in phase I clinical trials and no observed effect level based on QSAR modeling of the human maximum recommended daily dose (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15546675 AND SRC:MED&resulttype=core&format=json

5 January 2020

phase I clinical trial

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based on heuristic

inferred from title

author name string

Joseph F Contrera

1

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15546675 AND SRC:MED&resulttype=core&format=json

5 January 2020

Edwin J Matthews

2

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15546675 AND SRC:MED&resulttype=core&format=json

5 January 2020

Naomi L Kruhlak

3

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15546675 AND SRC:MED&resulttype=core&format=json

5 January 2020

R Daniel Benz

4

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15546675 AND SRC:MED&resulttype=core&format=json

5 January 2020

publication date

1 December 2004

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5 January 2020

Regulatory Toxicology and Pharmacology

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15546675 AND SRC:MED&resulttype=core&format=json

5 January 2020

40

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5 January 2020

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15546675 AND SRC:MED&resulttype=core&format=json

5 January 2020

185-206

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15546675 AND SRC:MED&resulttype=core&format=json

5 January 2020

Carcinogenicity testing and the evaluation of regulatory requirements for pharmaceuticals

1 reference

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Predicting the carcinogenic potential of pharmaceuticals in rodents using molecular structural similarity and E-state indices

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A new highly specific method for predicting the carcinogenic potential of pharmaceuticals in rodents using enhanced MCASE QSAR-ES software

1 reference

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7 January 2021

Assessment of the health effects of chemicals in humans: I. QSAR estimation of the maximum recommended therapeutic dose (MRTD) and no effect level (NOEL) of organic chemicals based on clinical trial data

1 reference

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7 January 2021

Man versus beast: pharmacokinetic scaling in mammals

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Concordance of the toxicity of pharmaceuticals in humans and in animals

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Application of Genetic Function Approximation to Quantitative Structure-Activity Relationships and Quantitative Structure-Property Relationships

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Interspecific Scaling of Toxicity Data

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7 January 2021

Interspecies extrapolation: a reexamination of acute toxicity data

1 reference

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7 January 2021

Identifiers

10.1016/J.YRTPH.2004.08.004

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15546675 AND SRC:MED&resulttype=core&format=json

5 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15546675 AND SRC:MED&resulttype=core&format=json

5 January 2020

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