Constitutive activation of the MAPkinase p38 is critical for MMP-9 production and survival of B-CLL cells on bone marrow stromal cells (Q80860636)

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4 January 2020

title

Constitutive activation of the MAPkinase p38 is critical for MMP-9 production and survival of B-CLL cells on bone marrow stromal cells (English)

1 reference

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B-cell chronic lymphocytic leukemia

4 January 2020

main subject

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1

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4 January 2020

author name string

T Dechow

2

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4 January 2020

F Schneller

3

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4 January 2020

K Weick

4

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4 January 2020

M Oelsner

5

1 reference

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4 January 2020

C Peschel

6

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4 January 2020

T Decker

7

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publication date

1 December 2004

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4 January 2020

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4 January 2020

volume

18

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4 January 2020

issue

12

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4 January 2020

page(s)

1964-1970

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Modulation of NF-kappa B activity and apoptosis in chronic lymphocytic leukemia B cells

4 January 2020

cites work

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7 January 2021

B lymphocytes from patients with chronic lymphocytic leukemia contain signal transducer and activator of transcription (STAT) 1 and STAT3 constitutively phosphorylated on serine residues.

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7 January 2021

Constitutively activated phosphatidylinositol-3 kinase (PI-3K) is involved in the defect of apoptosis in B-CLL: association with protein kinase Cdelta.

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Transcription factor AP-1 regulation by mitogen-activated protein kinase signal transduction pathways.

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ERKs: a family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF

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The c-Jun N-terminal protein kinase family of mitogen-activated protein kinases (JNK MAPKs).

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A protein kinase involved in the regulation of inflammatory cytokine biosynthesis

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Mammalian MAP kinase signalling cascades

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Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine

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Characterization of the structure and function of a novel MAP kinase kinase (MKK6)

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Selective Activation of p38 Mitogen-activated Protein (MAP) Kinase Isoforms by the MAP Kinase Kinases MKK3 and MKK6

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A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells

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Regulation of the MEF2 family of transcription factors by p38

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Stress-induced phosphorylation and activation of the transcription factor CHOP (GADD153) by p38 MAP Kinase

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Production of matrix metalloproteinase-9 in early stage B-CLL: suppression by interferons

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Increased serum levels of matrix metalloproteinase-9 predict clinical outcome of patients with early B-cell chronic lymphocytic leukaemia

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Protein kinase C-zeta regulates transcription of the matrix metalloproteinase-9 gene induced by IL-1 and TNF-alpha in glioma cells via NF-kappa B

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7 January 2021

The p38 SAPK pathway regulates the expression of the MMP-9 collagenase via AP-1-dependent promoter activation

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7 January 2021

Lipopolysaccharide-mediated transcriptional activation of the human tissue factor gene in THP-1 monocytic cells requires both activator protein 1 and nuclear factor kappa B binding sites

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7 January 2021

Preclinical pharmacokinetics of SB-203580, a potent inhibitor of p38 mitogen-activated protein kinase

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Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

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The vitamin D3 analog EB1089 induces apoptosis via a p53-independent mechanism involving p38 MAP kinase activation and suppression of ERK activity in B-cell chronic lymphocytic leukemia cells in vitro

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7 January 2021

The chimeric anti-CD20 antibody rituximab induces apoptosis in B-cell chronic lymphocytic leukemia cells through a p38 mitogen activated protein-kinase-dependent mechanism

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7 January 2021

Targeting p38 MAPK inhibits multiple myeloma cell growth in the bone marrow milieu

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7 January 2021

Involvement of multiple signaling pathways in follicular lymphoma transformation: p38-mitogen-activated protein kinase as a target for therapy

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7 January 2021

Production of autoantibodies by CD5-expressing B lymphocytes from patients with chronic lymphocytic leukemia

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7 January 2021

Matrix metalloproteinases and processing of pro-TNF-alpha.

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7 January 2021

Spontaneous programmed death (apoptosis) of B-chronic lymphocytic leukaemia cells following their culture in vitro

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Protein kinase C-delta regulates thrombin-induced ICAM-1 gene expression in endothelial cells via activation of p38 mitogen-activated protein kinase.

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Specific blockade of the ERK pathway inhibits the invasiveness of tumor cells: down-regulation of matrix metalloproteinase-3/-9/-14 and CD44

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7 January 2021