Complete dissociation of motor neuron death from motor dysfunction by Bax deletion in a mouse model of ALS (Q80159256)

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29 December 2019

title

Complete dissociation of motor neuron death from motor dysfunction by Bax deletion in a mouse model of ALS (English)

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amyotrophic lateral sclerosis

29 December 2019

main subject

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6

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29 December 2019

author name string

Thomas W Gould

1

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29 December 2019

Robert R Buss

2

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29 December 2019

Sharon Vinsant

3

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29 December 2019

David Prevette

4

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29 December 2019

Woong Sun

5

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29 December 2019

Carol E Milligan

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29 December 2019

Ronald W Oppenheim

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29 December 2019

publication date

1 August 2006

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29 December 2019

published in

Journal of Neuroscience

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volume

26

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issue

34

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29 December 2019

page(s)

8774-8786

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Lack of apoptosis in mice with ALS

29 December 2019

cites work

1 reference

12 December 2020

Neonatal partial denervation results in nodal but not terminal sprouting and a decrease in efficacy of remaining neuromuscular junctions in rat soleus muscle.

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12 December 2020

Bax and Bcl-2 interaction in a transgenic mouse model of familial amyotrophic lateral sclerosis

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12 December 2020

Early and selective loss of neuromuscular synapse subtypes with low sprouting competence in motoneuron diseases

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12 December 2020

Formation of high molecular weight complexes of mutant Cu, Zn-superoxide dismutase in a mouse model for familial amyotrophic lateral sclerosis.

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12 December 2020

Imaging neuronal subsets in transgenic mice expressing multiple spectral variants of GFP

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12 December 2020

Caspase-1 and -3 are sequentially activated in motor neuron death in Cu,Zn superoxide dismutase-mediated familial amyotrophic lateral sclerosis

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12 December 2020

Mitochondrial abnormalities in Alzheimer's disease.

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12 December 2020

Early vacuolization and mitochondrial damage in motor neurons of FALS mice are not associated with apoptosis or with changes in cytochrome oxidase histochemical reactivity.

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12 December 2020

From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS

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12 December 2020

Axonal self-destruction and neurodegeneration

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12 December 2020

Disruption of dynein/dynactin inhibits axonal transport in motor neurons causing late-onset progressive degeneration.

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12 December 2020

Dynactin is necessary for synapse stabilization.

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12 December 2020

Programmed cell death in amyotrophic lateral sclerosis

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12 December 2020

Aggresomes protect cells by enhancing the degradation of toxic polyglutamine-containing protein

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12 December 2020

BAK alters neuronal excitability and can switch from anti- to pro-death function during postnatal development

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12 December 2020

Inhibiting axon degeneration and synapse loss attenuates apoptosis and disease progression in a mouse model of motoneuron disease

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12 December 2020

Mutations in dynein link motor neuron degeneration to defects in retrograde transport

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12 December 2020

Dissociation between neurodegeneration and caspase-11-mediated activation of caspase-1 and caspase-3 in a mouse model of amyotrophic lateral sclerosis

1 reference

12 December 2020

VEGF is a modifier of amyotrophic lateral sclerosis in mice and humans and protects motoneurons against ischemic death

1 reference

12 December 2020

Neuromuscular development after the prevention of naturally occurring neuronal death by Bax deletion

1 reference

12 December 2020

Wild-Type Nonneuronal Cells Extend Survival of SOD1 Mutant Motor Neurons in ALS Mice

1 reference

12 December 2020

Axonal degeneration in paraplegin-deficient mice is associated with abnormal mitochondria and impairment of axonal transport

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12 December 2020

Amyotrophic lateral sclerosis is a distal axonopathy: evidence in mice and man

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12 December 2020

The function of neurotrophic factor receptors expressed by the developing adductor motor pool in vivo.

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12 December 2020

Toxicity of familial ALS-linked SOD1 mutants from selective recruitment to spinal mitochondria.

1 reference

12 December 2020

Amyotrophic lateral sclerosis-associated SOD1 mutant proteins bind and aggregate with Bcl-2 in spinal cord mitochondria

1 reference

12 December 2020

Cytoplasmic dynein regulates the subcellular distribution of mitochondria by controlling the recruitment of the fission factor dynamin-related protein-1.

1 reference

12 December 2020

Bax deletion prevents neuronal loss but not neurological symptoms in a transgenic model of inherited prion disease.

1 reference

12 December 2020

The neuroprotective factor Wlds does not attenuate mutant SOD1-mediated motor neuron disease

1 reference

12 December 2020

Cytochrome c association with the inner mitochondrial membrane is impaired in the CNS of G93A-SOD1 mice.

1 reference

12 December 2020

Schwann cells upregulate vascular endothelial growth factor secondary to chronic nerve compression injury

1 reference

12 December 2020

Botulinum neurotoxin C initiates two different programs for neurite degeneration and neuronal apoptosis

1 reference

12 December 2020

Mutant superoxide dismutase disrupts cytoplasmic dynein in motor neurons

1 reference

12 December 2020

Synaptic mitochondria are critical for mobilization of reserve pool vesicles at Drosophila neuromuscular junctions

1 reference

12 December 2020

The GTPase dMiro is required for axonal transport of mitochondria to Drosophila synapses.

1 reference

12 December 2020

A compensatory subpopulation of motor neurons in a mouse model of amyotrophic lateral sclerosis

1 reference

12 December 2020

Actions of BAX on mitochondrial channel activity and on synaptic transmission

1 reference

12 December 2020

Chromogranin-mediated secretion of mutant superoxide dismutase proteins linked to amyotrophic lateral sclerosis

1 reference

12 December 2020

Selective vulnerability and pruning of phasic motoneuron axons in motoneuron disease alleviated by CNTF

1 reference

12 December 2020

Calcium signaling pathways mediating synaptic potentiation triggered by amyotrophic lateral sclerosis IgG in motor nerve terminals.

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12 December 2020

Sensory nerve pathology in amyotrophic lateral sclerosis

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12 December 2020

Calcitonin gene-related peptide and chromogranin A: presence and intra-axonal transport in lumbar motor neurons in the rat, a comparison with synaptic vesicle antigens in immunohistochemical studies

1 reference

12 December 2020

Astrocytes increase in glial fibrillary acidic protein during retrograde changes of facial motor neurons

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12 December 2020

Degeneration and regeneration of ventral root motor fibers in amyotrophic lateral sclerosis. Morphometric studies of cervical ventral roots

1 reference

12 December 2020

Bcl-2 overexpression prevents motoneuron cell body loss but not axonal degeneration in a mouse model of a neurodegenerative disease

1 reference

12 December 2020

Bax-deficient mice with lymphoid hyperplasia and male germ cell death

1 reference

12 December 2020

An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria

1 reference

12 December 2020

Selective loss of glial glutamate transporter GLT‐1 in amyotrophic lateral sclerosis

1 reference

12 December 2020

Schwann cell processes guide regeneration of peripheral axons.

1 reference

12 December 2020

Neurites can remain viable after destruction of the neuronal soma by programmed cell death (apoptosis).

1 reference

12 December 2020

Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation

1 reference

12 December 2020

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

1 reference

12 December 2020

Age-dependent penetrance of disease in a transgenic mouse model of familial amyotrophic lateral sclerosis

1 reference

12 December 2020

Neuromuscular function impairment is not caused by motor neurone loss in FALS mice: an electromyographic study

1 reference

12 December 2020

Autoimmunity and ALS.

1 reference

12 December 2020

Bcl-2 promotes regeneration of severed axons in mammalian CNS

1 reference

12 December 2020

Bcl-2: Prolonging Life in a Transgenic Mouse Model of Familial Amyotrophic Lateral Sclerosis

1 reference

12 December 2020

Massive mitochondrial degeneration in motor neurons triggers the onset of amyotrophic lateral sclerosis in mice expressing a mutant SOD1

1 reference

12 December 2020

Relationship of microglial and astrocytic activation to disease onset and progression in a transgenic model of familial ALS.

1 reference

12 December 2020

Mitochondria and apoptosis

1 reference

12 December 2020

Aggregation and Motor Neuron Toxicity of an ALS-Linked SOD1 Mutant Independent from Wild-Type SOD1

1 reference

12 December 2020

Evidence for synaptic apoptosis

1 reference

12 December 2020

Aggresomes: a cellular response to misfolded proteins

1 reference

12 December 2020

10.1523/JNEUROSCI.2315-06.2006

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16928866 AND SRC:MED&resulttype=core&format=json

29 December 2019

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29 December 2019

PubMed publication ID

16928866

1 reference