Proteasome-mediated protein processing by bidirectional degradation initiated from an internal site (Q79918110)

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27 December 2019

title

Proteasome-mediated protein processing by bidirectional degradation initiated from an internal site (English)

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1

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27 December 2019

author name string

Stefan Jentsch

series ordinal

2

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publication date

16 July 2006

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Nature Structural & Molecular Biology

27 December 2019

published in

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volume

13

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issue

8

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page(s)

691-697

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Mechanisms underlying ubiquitination

27 December 2019

cites work

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A series of ubiquitin binding factors connects CDC48/p97 to substrate multiubiquitylation and proteasomal targeting

31 March 2020

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Opening doors into the proteasome.

31 March 2020

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Delivery of ubiquitinated substrates to protein-unfolding machines

31 March 2020

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Selective protein degradation: a journey's end within the proteasome

31 March 2020

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Proteasome and peptidase function in MHC-class-I-mediated antigen presentation

31 March 2020

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Taking a bite: proteasomal protein processing

31 March 2020

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Membrane-bound transcription factors: regulated release by RIP or RUP.

31 March 2020

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Mechanism of processing of the NF-kappa B2 p100 precursor: identification of the specific polyubiquitin chain-anchoring lysine residue and analysis of the role of NEDD8-modification on the SCF(beta-TrCP) ubiquitin ligase

31 March 2020

1 reference

Generation of p50 subunit of NF-kappa B by processing of p105 through an ATP-dependent pathway.

31 March 2020

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The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B

31 March 2020

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Activation of a membrane-bound transcription factor by regulated ubiquitin/proteasome-dependent processing.

31 March 2020

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A conserved processing mechanism regulates the activity of transcription factors Cubitus interruptus and NF-κB

31 March 2020

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Sonic hedgehog signaling regulates Gli2 transcriptional activity by suppressing its processing and degradation

31 March 2020

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Regulation of the Hedgehog and Wingless signalling pathways by the F-box/WD40-repeat protein Slimb

31 March 2020

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An N-terminal region of Sp1 targets its proteasome-dependent degradation in vitro

31 March 2020

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Structural motifs involved in ubiquitin-mediated processing of the NF-kappaB precursor p105: roles of the glycine-rich region and a downstream ubiquitination domain

31 March 2020

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Mobilization of processed, membrane-tethered SPT23 transcription factor by CDC48(UFD1/NPL4), a ubiquitin-selective chaperone

31 March 2020

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ATP-dependent proteases degrade their substrates by processively unraveling them from the degradation signal

31 March 2020

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Cotranslational dimerization of the Rel homology domain of NF-kappaB1 generates p50-p105 heterodimers and is required for effective p50 production

31 March 2020

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Cotranslational Biogenesis of NF-κB p50 by the 26S Proteasome

31 March 2020

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The 20S proteasome processes NF-kappaB1 p105 into p50 in a translation-independent manner

31 March 2020

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NF-κB p105 Processing via the Ubiquitin-Proteasome Pathway

31 March 2020

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SCF(beta)(-TrCP) ubiquitin ligase-mediated processing of NF-kappaB p105 requires phosphorylation of its C-terminus by IkappaB kinase

31 March 2020

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Endoproteolytic activity of the proteasome

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Concurrent translocation of multiple polypeptide chains through the proteasomal degradation channel

31 March 2020

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Binding of a specific ligand inhibits import of a purified precursor protein into mitochondria.

31 March 2020

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Methotrexate inhibits proteolysis of dihydrofolate reductase by the N-end rule pathway.

31 March 2020

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Protein unfolding--an important process in vivo?

31 March 2020

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Role of the proteasome in membrane extraction of a short-lived ER-transmembrane protein

31 March 2020

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S. cerevisiae 26S protease mutants arrest cell division in G2/metaphase

31 March 2020

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Role of 26S proteasome and HRD genes in the degradation of 3-hydroxy-3-methylglutaryl-CoA reductase, an integral endoplasmic reticulum membrane protein

31 March 2020

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Regulated degradation of HMG-CoA reductase, an integral membrane protein of the endoplasmic reticulum, in yeast

31 March 2020

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Proteolysis and sterol regulation

31 March 2020

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An unstructured initiation site is required for efficient proteasome-mediated degradation

31 March 2020

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Processing of p105 is inhibited by docking of p50 active subunits to the ankyrin repeat domain, and inhibition is alleviated by signaling via the carboxyl-terminal phosphorylation/ ubiquitin-ligase binding domain

31 March 2020

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The degradation signal in a short-lived protein

31 March 2020

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Epitope tagging of yeast genes using a PCR-based strategy: more tags and improved practical routines

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/NSMB1122

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27 December 2019

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