Deficiency of the complement regulator CD59a enhances disease severity, demyelination and axonal injury in murine acute experimental allergic encephalomyelitis (Q79314618)

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scientific article published on 01 January 2004

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English	Deficiency of the complement regulator CD59a enhances disease severity, demyelination and axonal injury in murine acute experimental allergic encephalomyelitis	scientific article published on 01 January 2004

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scholarly article

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14631387 AND SRC:MED&resulttype=core&format=json

21 December 2019

Deficiency of the complement regulator CD59a enhances disease severity, demyelination and axonal injury in murine acute experimental allergic encephalomyelitis (English)

1 reference

Europe PubMed Central

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21 December 2019

1

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Europe PubMed Central

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21 December 2019

Christopher Linington

4

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21 December 2019

6

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Europe PubMed Central

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21 December 2019

Bryan Paul Morgan

7

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21 December 2019

author name string

James William Neal

2

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21 December 2019

Mark Raymond Griffiths

3

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21 December 2019

Marina Botto

5

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21 December 2019

publication date

1 January 2004

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21 December 2019

Laboratory Investigation

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21 December 2019

84

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21 December 2019

1

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21 December 2019

21-28

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21 December 2019

Multiple sclerosis

1 reference

https://api.crossref.org/works/10.1038/LABINVEST.3700015

7 January 2021

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Multiple sclerosis: in situ evidence for antibody- and complement-mediated demyelination

1 reference

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7 January 2021

based on heuristic

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Multiple sclerosis and chronic autoimmune encephalomyelitis: a comparative quantitative study of axonal injury in active, inactive, and remyelinated lesions

1 reference

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7 January 2021

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Heterogeneity of multiple sclerosis lesions: implications for the pathogenesis of demyelination

1 reference

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7 January 2021

based on heuristic

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Persistent functional deficit in multiple sclerosis and autosomal dominant cerebellar ataxia is associated with axon loss

1 reference

https://api.crossref.org/works/10.1038/LABINVEST.3700015

7 January 2021

based on heuristic

inferred from DOI database lookup

TISSUE CULTURE STUDIES OF DEMYELINATION

1 reference

https://api.crossref.org/works/10.1038/LABINVEST.3700015

7 January 2021

based on heuristic

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Vesicular removal by oligodendrocytes of membrane attack complexes formed by activated complement

1 reference

https://api.crossref.org/works/10.1038/LABINVEST.3700015

7 January 2021

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Immunohistochemical localisation of terminal complement component C9 in experimental allergic encephalomyelitis

1 reference

https://api.crossref.org/works/10.1038/LABINVEST.3700015

7 January 2021

based on heuristic

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Immunocytochemical localization of the terminal complement complex in multiple sclerosis.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

The role of complement in the pathogenesis of experimental allergic encephalomyelitis

1 reference

https://api.crossref.org/works/10.1038/LABINVEST.3700015

7 January 2021

based on heuristic

inferred from DOI database lookup

Attenuation of experimental autoimmune demyelination in complement-deficient mice

1 reference

https://api.crossref.org/works/10.1038/LABINVEST.3700015

7 January 2021

based on heuristic

inferred from DOI database lookup

Cutting edge: C3, a key component of complement activation, is not required for the development of myelin oligodendrocyte glycoprotein peptide-induced experimental autoimmune encephalomyelitis in mice

1 reference

https://api.crossref.org/works/10.1038/LABINVEST.3700015

7 January 2021

based on heuristic

inferred from DOI database lookup

The Membrane Attack Complex of Complement Causes Severe Demyelination Associated with Acute Axonal Injury

1 reference

https://api.crossref.org/works/10.1038/LABINVEST.3700015

7 January 2021

based on heuristic

inferred from DOI database lookup

Attenuation of experimental allergic encephalomyelitis in complement component 6-deficient rats is associated with reduced complement C9 deposition, P-selectin expression, and cellular infiltrate in spinal cords

1 reference

https://api.crossref.org/works/10.1038/LABINVEST.3700015

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification of autoantibodies associated with myelin damage in multiple sclerosis

1 reference

https://api.crossref.org/works/10.1038/LABINVEST.3700015

7 January 2021

based on heuristic

inferred from DOI database lookup

Measurement of complement components in cerebral spinal fluid by radioimmunoassay in patients with multiple sclerosis

1 reference

https://api.crossref.org/works/10.1038/LABINVEST.3700015

7 January 2021

based on heuristic

inferred from DOI database lookup

Intrathecal complement activation in neurological diseases evaluated by analysis of the terminal complement complex

1 reference

https://api.crossref.org/works/10.1038/LABINVEST.3700015

7 January 2021

based on heuristic

inferred from DOI database lookup

Immune mechanisms in the pathogenesis of demyelinating diseases

1 reference

https://api.crossref.org/works/10.1038/LABINVEST.3700015

7 January 2021

based on heuristic

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A role for humoral mechanisms in the pathogenesis of Devic's neuromyelitis optica

1 reference

https://api.crossref.org/works/10.1038/LABINVEST.3700015

7 January 2021

based on heuristic

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Identification and functional characterization of a new gene encoding the mouse terminal complement inhibitor CD59

1 reference

https://api.crossref.org/works/10.1038/LABINVEST.3700015

7 January 2021

based on heuristic

inferred from DOI database lookup

Characterization of the mouse analogues of CD59 using novel monoclonal antibodies: tissue distribution and functional comparison

1 reference

https://api.crossref.org/works/10.1038/LABINVEST.3700015

7 January 2021

based on heuristic

inferred from DOI database lookup

Targeted deletion of the CD59 gene causes spontaneous intravascular hemolysis and hemoglobinuria

1 reference

https://api.crossref.org/works/10.1038/LABINVEST.3700015

7 January 2021

based on heuristic

inferred from DOI database lookup

Treatment with anti-interferon-gamma monoclonal antibodies modifies experimental autoimmune encephalomyelitis in interferon-gamma receptor knockout mice.

1 reference

https://api.crossref.org/works/10.1038/LABINVEST.3700015

7 January 2021

based on heuristic

inferred from DOI database lookup

The N-terminal domain of the myelin oligodendrocyte glycoprotein (MOG) induces acute demyelinating experimental autoimmune encephalomyelitis in the Lewis rat

1 reference

https://api.crossref.org/works/10.1038/LABINVEST.3700015

7 January 2021

based on heuristic

inferred from DOI database lookup

The regional distribution of myelin oligodendrocyte glycoprotein (MOG) in the developing rat CNS: an in vivo immunohistochemical study

1 reference

https://api.crossref.org/works/10.1038/LABINVEST.3700015

7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular basis of paroxysmal nocturnal hemoglobinuria

1 reference

https://api.crossref.org/works/10.1038/LABINVEST.3700015

7 January 2021

based on heuristic

inferred from DOI database lookup

Killing of rat glial cells by complement: deficiency of the rat analogue of CD59 is the cause of oligodendrocyte susceptibility to lysis

1 reference

https://api.crossref.org/works/10.1038/LABINVEST.3700015

7 January 2021

based on heuristic

inferred from DOI database lookup

Spontaneous classical pathway activation and deficiency of membrane regulators render human neurons susceptible to complement lysis

1 reference

https://api.crossref.org/works/10.1038/LABINVEST.3700015

7 January 2021

based on heuristic

inferred from DOI database lookup

Genomic structure, functional comparison, and tissue distribution of mouse Cd59a and Cd59b

1 reference

https://api.crossref.org/works/10.1038/LABINVEST.3700015

7 January 2021

based on heuristic

inferred from DOI database lookup

Deficiency of the mouse complement regulatory protein mCd59b results in spontaneous hemolytic anemia with platelet activation and progressive male infertility

1 reference

https://api.crossref.org/works/10.1038/LABINVEST.3700015

7 January 2021

based on heuristic

inferred from DOI database lookup

Rat and human myelin oligodendrocyte glycoproteins induce experimental autoimmune encephalomyelitis by different mechanisms in C57BL/6 mice

1 reference

https://api.crossref.org/works/10.1038/LABINVEST.3700015

7 January 2021

based on heuristic

inferred from DOI database lookup

Selective unresponsiveness to conformational B cell epitopes of the myelin oligodendrocyte glycoprotein in H-2b mice

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Inherited complete deficiency of 20-kilodalton homologous restriction factor (CD59) as a cause of paroxysmal nocturnal hemoglobinuria

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Deficiency of complement defense protein CD59 may contribute to neurodegeneration in Alzheimer's disease

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

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