The V(D)J recombinase efficiently cleaves and transposes signal joints (Q78025745)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11983177 AND SRC:MED&resulttype=core&format=json

10 December 2019

title

The V(D)J recombinase efficiently cleaves and transposes signal joints (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11983177 AND SRC:MED&resulttype=core&format=json

10 December 2019

author name string

Matthew B Neiditch

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11983177 AND SRC:MED&resulttype=core&format=json

10 December 2019

Gregory S Lee

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11983177 AND SRC:MED&resulttype=core&format=json

10 December 2019

Leslie E Huye

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11983177 AND SRC:MED&resulttype=core&format=json

10 December 2019

Vicky L Brandt

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11983177 AND SRC:MED&resulttype=core&format=json

10 December 2019

David B Roth

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11983177 AND SRC:MED&resulttype=core&format=json

10 December 2019

publication date

1 April 2002

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11983177 AND SRC:MED&resulttype=core&format=json

10 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11983177 AND SRC:MED&resulttype=core&format=json

10 December 2019

volume

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11983177 AND SRC:MED&resulttype=core&format=json

10 December 2019

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11983177 AND SRC:MED&resulttype=core&format=json

10 December 2019

page(s)

871-878

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11983177 AND SRC:MED&resulttype=core&format=json

RAG1 and RAG2 form a stable postcleavage synaptic complex with DNA containing signal ends in V(D)J recombination

10 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00494-X

7 January 2021

Transposition mediated by RAG1 and RAG2 and its implications for the evolution of the immune system

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00494-X

7 January 2021

Changes in thymic function with age and during the treatment of HIV infection

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00494-X

7 January 2021

Initiation of V(D)J recombination in vitro obeying the 12/23 rule

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00494-X

7 January 2021

Late embryonic lethality and impaired V(D)J recombination in mice lacking DNA ligase IV

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00494-X

7 January 2021

DNA ligase IV is essential for V(D)J recombination and DNA double-strand break repair in human precursor lymphocytes

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00494-X

7 January 2021

Ku70-deficient embryonic stem cells have increased ionizing radiosensitivity, defective DNA end-binding activity, and inability to support V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00494-X

7 January 2021

Intermolecular V(D)J recombination is prohibited specifically at the joining step

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00494-X

7 January 2021

Extrachromosomal DNA substrates in pre-B cells undergo inversion or deletion at immunoglobulin V-(D)-J joining signals

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00494-X

7 January 2021

Assembly of a 12/23 paired signal complex: a critical control point in V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00494-X

7 January 2021

DNA transposition by the RAG1 and RAG2 proteins: a possible source of oncogenic translocations

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00494-X

7 January 2021

Differential requirements for cis and trans V(D)J cleavage: effects of substrate length

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00494-X

7 January 2021

Junctional sequences of T cell receptor gamma delta genes: implications for gamma delta T cell lineages and for a novel intermediate of V-(D)-J joining.

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00494-X

7 January 2021

Mutational analysis of RAG1 and RAG2 identifies three catalytic amino acids in RAG1 critical for both cleavage steps of V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00494-X

7 January 2021

Targeted transposition by the V(D)J recombinase

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00494-X

7 January 2021

DNA elements are asymmetrically joined during the site-specific recombination of kappa immunoglobulin genes

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00494-X

7 January 2021

Novel strand exchanges in V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00494-X

7 January 2021

The XRCC4 gene encodes a novel protein involved in DNA double-strand break repair and V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00494-X

7 January 2021

T-cell receptor alpha locus V(D)J recombination by-products are abundant in thymocytes and mature T cells

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00494-X

7 January 2021

Cleavage at a V(D)J recombination signal requires only RAG1 and RAG2 proteins and occurs in two steps

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00494-X

7 January 2021

P nucleotides in V(D)J recombination: a fine-structure analysis

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00494-X

7 January 2021

Artemis, a novel DNA double-strand break repair/V(D)J recombination protein, is mutated in human severe combined immune deficiency.

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00494-X

7 January 2021

Characterization of excised DNA intermediates associated with V(D)J recombination at the T-cell receptor delta locus

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00494-X

7 January 2021

RAG transposase can capture and commit to target DNA before or after donor cleavage

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00494-X

7 January 2021

Requirement for Ku80 in growth and immunoglobulin V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00494-X

7 January 2021

Separation-of-function mutants reveal critical roles for RAG2 in both the cleavage and joining steps of V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00494-X

7 January 2021

Formation and resolution of double-strand break intermediates in V(D)J rearrangement

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00494-X

7 January 2021

VDJ recombination: a transposase goes to work

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00494-X

7 January 2021

Unequal access: regulating V(D)J recombination through chromatin remodeling

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00494-X

7 January 2021

V(D)J recombination: broken DNA molecules with covalently sealed (hairpin) coding ends in scid mouse thymocytes

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00494-X

7 January 2021

Characterization of broken DNA molecules associated with V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00494-X

7 January 2021

Expression and V(D)J recombination activity of mutated RAG-1 proteins

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00494-X

7 January 2021

Definition of a core region of RAG-2 that is functional in V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00494-X

7 January 2021

V(D)J recombination: modulation of RAG1 and RAG2 cleavage activity on 12/23 substrates by whole cell extract and DNA-bending proteins

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00494-X

7 January 2021

Double-strand signal sequence breaks in V(D)J recombination are blunt, 5'-phosphorylated, RAG-dependent, and cell cycle regulated

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00494-X

7 January 2021

Joining-deficient RAG1 mutants block V(D)J recombination in vivo and hairpin opening in vitro

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00494-X

7 January 2021

V(D)J recombination: signal and coding joint resolution are uncoupled and depend on parallel synapsis of the sites

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00494-X

7 January 2021

Accessibility control of variable region gene assembly during T-cell development.

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00494-X

7 January 2021

The homeodomain region of Rag-1 reveals the parallel mechanisms of bacterial and V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00494-X

7 January 2021

The 12/23 rule is enforced at the cleavage step of V(D)J recombination in vivo

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00494-X

7 January 2021

Initiation of V(D)J recombination in vivo: role of recombination signal sequences in formation of single and paired double-strand breaks

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00494-X

7 January 2021

Impairment of V(D)J recombination in double-strand break repair mutants

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00494-X

7 January 2021

The RAG1 and RAG2 proteins establish the 12/23 rule in V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00494-X

7 January 2021

The nicking step in V(D)J recombination is independent of synapsis: implications for the immune repertoire

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00494-X

7 January 2021

Characterization of coding ends in thymocytes of scid mice: Implications for the mechanism of V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00494-X

7 January 2021

Ku86-deficient mice exhibit severe combined immunodeficiency and defective processing of V(D)J recombination intermediates

1 reference

https://api.crossref.org/works/10.1016/S1097-2765(02)00494-X

7 January 2021

10.1016/S1097-2765(02)00494-X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11983177 AND SRC:MED&resulttype=core&format=json

10 December 2019

1 reference