Chemotherapeutic potential of phosphodiesterase inhibitors (Q77297316)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9736920 AND SRC:MED&resulttype=core&format=json

4 December 2019

review article

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title

Chemotherapeutic potential of phosphodiesterase inhibitors (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9736920 AND SRC:MED&resulttype=core&format=json

4 December 2019

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M J Perry

1

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4 December 2019

G A Higgs

series ordinal

2

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4 December 2019

publication date

1 August 1998

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Current Opinion in Chemical Biology

4 December 2019

published in

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4 December 2019

volume

2

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4 December 2019

issue

4

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4 December 2019

page(s)

472-481

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Tailoring cAMP-signalling responses through isoform multiplicity

4 December 2019

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Antiplatelet and antiproliferative effects of SCH 51866, a novel type 1 and type 5 phosphodiesterase inhibitor

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Isolation and characterization of human cDNAs encoding a cGMP-stimulated 3′,5′-cyclic nucleotide phosphodiesterase

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Rapid regulation of PDE-2 and PDE-4 cyclic AMP phosphodiesterase activity following ligation of the T cell antigen receptor on thymocytes: analysis using the selective inhibitors erythro-9-(2-hydroxy-3-nonyl)-adenine (EHNA) and rolipram.

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Activation of cGMP-stimulated phosphodiesterase by nitroprusside limits cAMP accumulation in human platelets: effects on platelet aggregation

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Isozyme selective inhibition of cGMP-stimulated cyclic nucleotide phosphodiesterases by erythro-9-(2-hydroxy-3-nonyl) adenine

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cGMP-stimulated cyclic nucleotide phosphodiesterase regulates the basal calcium current in human atrial myocytes

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Characterization of two recombinant PDE3 (cGMP-inhibited cyclic nucleotide phosphodiesterase) isoforms, RcGIP1 and HcGIP2, expressed in NIH 3006 murine fibroblasts and Sf9 insect cells

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Structure, localization, and regulation of cGMP-inhibited phosphodiesterase (PDE3)

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Phosphorylation and Activation of Hormone-Sensitive Adipocyte Phosphodiesterase Type 3B

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Cyclic AMP phosphodiesterases in human lymphocytes

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Effect of oral milrinone on mortality in severe chronic heart failure. The PROMISE Study Research Group

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7 January 2021

The role of phosphodiesterase inhibitors in heart failure

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7 January 2021

Calcium Sensitising Agents in Heart Failure

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Effect of pimobendan on exercise capacity in patients with heart failure: main results from the Pimobendan in Congestive Heart Failure (PICO) trial

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Identification of cyclic AMP phosphodiesterases 3, 4 and 7 in human CD4 and CD8 T-lymphocytes: role in regulating proliferation and the biosynthesis of interleukin-2

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7 January 2021

PDE isoenzymes as targets for anti-asthma drugs

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7 January 2021

PDE 4 inhibitors: the use of molecular cloning in the design and development of novel drugs

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7 January 2021

Selective inhibition of one of the cyclic AMP phosphodiesterases from rat brain by the neurotropic compound rolipram

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7 January 2021

Phosphodiesterase isozymes: molecular targets for novel antiasthma agents

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7 January 2021

Rolipram in major depressive disorder: results of a double-blind comparative study with imipramine

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7 January 2021

EEG mapping and psychopharmacological studies with denbufylline in SDAT and MID

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7 January 2021

Proposal for Pharmacologically Distinct Conformers of PDE4 Cyclic AMP Phosphodiesterases

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7 January 2021

Biarylcarboxylic acids and -amides: inhibition of phosphodiesterase type IV versus [3H]rolipram binding activity and their relationship to emetic behavior in the ferret

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7 January 2021

Human phosphodiesterase 4A: characterization of full-length and truncated enzymes expressed in COS cells

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7 January 2021

Human Recombinant Phosphodiesterase 4B2B Binds (R)-Rolipram at a Single Site with Two Affinities

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7 January 2021

CDP840: a novel inhibitor of PDE-4.

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7 January 2021

The effect of a novel orally active selective PDE4 isoenzyme inhibitor (CDP840) on allergen-induced responses in asthmatic subjects

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7 January 2021

Regulation of tumour necrosis factor production by adrenal hormones in vivo: insights into the antiinflammatory activity of rolipram

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7 January 2021

Characterization of guinea-pig eosinophil phosphodiesterase activity. Assessment of its involvement in regulating superoxide generation

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7 January 2021

Effects of the mixed phosphodiesterase III/IV inhibitor, zardaverine, on airway function in patients with chronic airflow obstruction

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7 January 2021

Type 4 phosphodiesterase inhibitors have clinical and in vitro anti-inflammatory effects in atopic dermatitis

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7 January 2021

Papaverine and Ro 20-1724 Inhibit Cyclic Nucleotide Phosphodiesterase Activity and Increase Cyclic AMP Levels in Psoriatic Epidermis In Vitro

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7 January 2021

Hydropathic Analysis and Mutagenesis of the Catalytic Domain of the cGMP-Binding cGMP-Specific Phosphodiesterase (PDE5). cGMP versus cAMP Substrate Selectivity

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Potential Roles of Conserved Amino Acids in the Catalytic Domain of the cGMP-binding cGMP-specific Phosphodiesterase (PDE5)

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Binding of cGMP to both allosteric sites of cGMP-binding cGMP-specific phosphodiesterase (PDE5) is required for its phosphorylation

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7 January 2021

Cyclic nucleotide phosphodiesterases and vascular smooth muscle

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7 January 2021

Sildenafil (VIAGRATM), a potent and selective inhibitor of type 5 cGMP phosphodiesterase with utility for the treatment of male erectile dysfunction

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7 January 2021

Synthesis and cyclic GMP phosphodiesterase inhibitory activity of a series of 6-phenylpyrazolo[3,4-d]pyrimidones

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7 January 2021

Neurotransmission and the contraction and relaxation of penile erectile tissues

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7 January 2021

Effects of sildenafil, a type-5 cGMP phosphodiesterase inhibitor, and papaverine on cyclic GMP and cyclic AMP levels in the rabbit corpus cavernosum in vitro

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7 January 2021

A new cyclic nucleotide phosphodiesterase isozyme expressed in the T-lymphocyte cell lines

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7 January 2021

Alternative splicing of the high affinity cAMP-specific phosphodiesterase (PDE7A) mRNA in human skeletal muscle and heart

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7 January 2021

Identification and tissue-specific expression of PDE7 phosphodiesterase splice variants

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7 January 2021

Isolation and Characterization of PDE8A, a Novel Human cAMP-Specific Phosphodiesterase

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7 January 2021

Isolation and characterization of PDE9A, a novel human cGMP-specific phosphodiesterase

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7 January 2021

Identification and characterization of a novel family of cyclic nucleotide phosphodiesterases

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7 January 2021

10.1016/S1367-5931(98)80123-3

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9736920 AND SRC:MED&resulttype=core&format=json

4 December 2019

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