Biochemical and Genetic Tests for Inhibitors ofLeishmaniaPteridine Pathways (Q73882841)

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7 November 2019

title

Biochemical and genetic tests for inhibitors of Leishmania pteridine pathways (English)

1 reference

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7 November 2019

Biochemical and Genetic Tests for Inhibitors ofLeishmaniaPteridine Pathways (English)

1 reference

https://api.crossref.org/works/10.1006/EXPR.1997.4207

24 November 2024

Biochemical and Genetic Tests for Inhibitors of Leishmania Pteridine Pathways (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:9398595

28 November 2024

author name string

L. W. Hardy

1

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24 November 2024

S. M. Beverley

4

1 reference

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24 November 2024

Hardy LW

1

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28 November 2024

Matthews W

2

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28 November 2024

Nare B

3

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28 November 2024

Beverley SM

4

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28 November 2024

language of work or name

English

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National Center for Biotechnology Information

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24 November 2024

publication date

1 November 1997

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7 November 2019

November 1997

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=9371081

full work available at URL

24 November 2024

https://api.elsevier.com/content/article/PII:S0014489497942077?httpAccept=text/xml

1 reference

https://api.crossref.org/works/10.1006/EXPR.1997.4207

https://api.elsevier.com/content/article/PII:S0014489497942077?httpAccept=text/plain

24 November 2024

1 reference

https://api.crossref.org/works/10.1006/EXPR.1997.4207

Experimental Parasitology

24 November 2024

published in

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7 November 2019

volume

87

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7 November 2019

issue

3

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7 November 2019

page(s)

157-169

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Structural features of 5,10-dideaza-5,6,7,8-tetrahydrofolate that determine inhibition of mammalian glycinamide ribonucleotide formyltransferase

7 November 2019

cites work

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PTR1: a reductase mediating salvage of oxidized pteridines and methotrexate resistance in the protozoan parasite Leishmania major.

24 November 2024

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Antileishmanial activities of 2,4-diaminoquinazoline putative dihydrofolate reductase inhibitors

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Gene amplification in Leishmania

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Unstable DNA amplifications in methotrexate-resistant Leishmania consist of extrachromosomal circles which relocalize during stabilization.

24 November 2024

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New mechanisms of drug resistance in parasitic protozoa

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Tight-binding inhibitors-I. Kinetic behavior

24 November 2024

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Overproduction of a bifunctional thymidylate synthetase-dihydrofolate reductase and DNA amplification in methotrexate-resistant Leishmania tropica

24 November 2024

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Gene replacement in parasitic protozoa

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Double targeted gene replacement for creating null mutants

24 November 2024

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The Effect of Trimethoprim and Sulfamethoxazole on Toxoplasma Gondii in Vitro and in Vivo *

24 November 2024

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Selection against the dihydrofolate reductase-thymidylate synthase (DHFR-TS) locus as a probe of genetic alterations in Leishmania major.

24 November 2024

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Quinazolines as inhibitors of dihydrofolate reductase. 4. Classical analogues of folic and isofolic acids

24 November 2024

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Bifunctional thymidylate synthase-dihydrofolate reductase in protozoa

24 November 2024

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The threonine-sensitive homoserine dehydrogenase and aspartokinase activities of Escherichia coli K 12. Binding of threonine and of pyridine nucleotides: stoichiometry and optical effects

24 November 2024

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Stable transfection of the human parasite Leishmania major delineates a 30-kilobase region sufficient for extrachromosomal replication and expression

24 November 2024

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Altered structural and mechanistic properties of mutant dihydropteridine reductases

24 November 2024

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The roles of pteridine reductase 1 and dihydrofolate reductase-thymidylate synthase in pteridine metabolism in the protozoan parasite Leishmania major

24 November 2024

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A novel antifolate resistance gene on the amplified H circle of Leishmania.

24 November 2024

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Expression and site-directed mutagenesis of human dihydrofolate reductase

24 November 2024

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Quinazoline analogues of folic acid as inhibitors of thymidylate synthetase from bacterial and mammalian sources

24 November 2024

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Effects of methotrexate and other antifolates on the growth and dihydrofolate reductase activity of Leishmania promastigotes

24 November 2024

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Selective inhibition of Leishmania dihydrofolate reductase and Leishmania growth by 5-benzyl-2,4-diaminopyrimidines

24 November 2024

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