Monoclonal anti-double-stranded DNA autoantibody stimulates the expression and release of IL-1beta, IL-6, IL-8, IL-10 and TNF-alpha from normal human mononuclear cells involving in the lupus pathogenesis (Q73537465)

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scientific article published on 01 March 2000

Language	Label	Description	Also known as
English	Monoclonal anti-double-stranded DNA autoantibody stimulates the expression and release of IL-1beta, IL-6, IL-8, IL-10 and TNF-alpha from normal human mononuclear cells involving in the lupus pathogenesis	scientific article published on 01 March 2000

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10712664 AND SRC:MED&resulttype=core&format=json

4 November 2019

Monoclonal anti-double-stranded DNA autoantibody stimulates the expression and release of IL-1beta, IL-6, IL-8, IL-10 and TNF-alpha from normal human mononuclear cells involving in the lupus pathogenesis (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10712664 AND SRC:MED&resulttype=core&format=json

4 November 2019

author name string

K H Sun

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10712664 AND SRC:MED&resulttype=core&format=json

4 November 2019

C L Yu

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10712664 AND SRC:MED&resulttype=core&format=json

4 November 2019

S J Tang

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10712664 AND SRC:MED&resulttype=core&format=json

4 November 2019

G H Sun

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10712664 AND SRC:MED&resulttype=core&format=json

4 November 2019

publication date

1 March 2000

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10712664 AND SRC:MED&resulttype=core&format=json

4 November 2019

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10712664 AND SRC:MED&resulttype=core&format=json

4 November 2019

99

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10712664 AND SRC:MED&resulttype=core&format=json

4 November 2019

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10712664 AND SRC:MED&resulttype=core&format=json

4 November 2019

352-360

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10712664 AND SRC:MED&resulttype=core&format=json

4 November 2019

Interleukin-10 prevents spontaneous death of germinal center B cells by induction of the bcl-2 protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/10712664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polyclonal IgG anti-dsDNA antibodies exert cytotoxic effect on cultured rat mesangial cells by binding to cell membrane and augmenting apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/10712664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin 6 promotes murine lupus in NZB/NZW F1 mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/10712664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abnormal splenic and thymic IL-4 and TNF-alpha expression in MRL-lpr/lpr mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/10712664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of interleukin 10 in the B lymphocyte hyperactivity and autoantibody production of human systemic lupus erythematosus

1 reference

https://pubmed.ncbi.nlm.nih.gov/10712664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elevated serum interleukin-6 levels associated with active disease in systemic connective tissue disorders.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10712664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative polymerase chain reaction analysis reveals marked overexpression of interleukin-1 beta, interleukin-1 and interferon-gamma mRNA in the lymph nodes of lupus-prone mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/10712664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-dsDNA antibodies cross-react with ribosomal P proteins expressed on the surface of glomerular mesangial cells to exert a cytostatic effect

1 reference

https://pubmed.ncbi.nlm.nih.gov/10712664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High levels of TH2 cytokine gene expression in systemic lupus erythematosus

1 reference

https://pubmed.ncbi.nlm.nih.gov/10712664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased release of von Willebrand factor antigen from endothelial cells by anti-DNA autoantibodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/10712664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Systemic lupus erythematosus

1 reference

https://pubmed.ncbi.nlm.nih.gov/10712664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The expression of acidic ribosomal phosphoproteins on the surface membrane of different tissues in autoimmune and normal mice which are the target molecules for anti-double-stranded DNA antibodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/10712664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-DNA autoantibodies stimulate the release of interleukin-1 and interleukin-6 from endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10712664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytokine gene expression in the MRL/lpr model of lupus nephritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/10712664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumour necrosis factor alpha and its soluble receptors parallel clinical disease and autoimmune activity in systemic lupus erythematosus

1 reference

https://pubmed.ncbi.nlm.nih.gov/10712664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Manipulation of the Th1/Th2 balance in autoimmune disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/10712664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytokines in autoimmunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/10712664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Roles of IL-4 and IL-12 in the development of lupus in NZB/W F1 mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/10712664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kinetics of cytokine production in experimental systemic lupus erythematosus: involvement of T helper cell 1/T helper cell 2-type cytokines in disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/10712664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Roles of interferon-gamma and interleukin-4 in murine lupus

1 reference

https://pubmed.ncbi.nlm.nih.gov/10712664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Receptor-mediated cellular entry of nuclear localizing anti-DNA antibodies via myosin 1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10712664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inflammatory cytokines enhance the in vivo clonal expansion and differentiation of antigen-activated CD4 T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10712664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytokine concentration in serum of lupus erythematosus patients: the effect on acute phase response

1 reference

https://pubmed.ncbi.nlm.nih.gov/10712664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Circulating interleukin-6 type cytokines in patients with systemic lupus erythematosus

1 reference

https://pubmed.ncbi.nlm.nih.gov/10712664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of Anti-DNA Autoantibodies on the Gene Expression of Interleukin 8, Transforming Growth Factor-β, and Nitric Oxide Synthase in Cultured Endothelial Cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10712664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polyreactive anti-DNA monoclonal antibodies and a derived peptide as vectors for the intracytoplasmic and intranuclear translocation of macromolecules

1 reference

https://pubmed.ncbi.nlm.nih.gov/10712664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunological studies concerning the nephritis of systemic lupus erythematosus

1 reference

https://pubmed.ncbi.nlm.nih.gov/10712664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pathogenesis of the glomerulonephritis of NZB/W mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/10712664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Continuous cultures of fused cells secreting antibody of predefined specificity

1 reference

https://pubmed.ncbi.nlm.nih.gov/10712664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glomerular cell culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/10712664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sensitive solid phase radioimmunoassay for the detection of anti-DNA autoantibodies.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10712664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cross-reactivity of human and murine anti-DNA antibodies with heparan sulfate. The major glycosaminoglycan in glomerular basement membranes

1 reference

https://pubmed.ncbi.nlm.nih.gov/10712664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Monoclonal murine anti-DNA antibody interacts with living mononuclear cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10712664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel and enhanced IL-1 gene expression in autoimmune mice with lupus

1 reference

https://pubmed.ncbi.nlm.nih.gov/10712664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The abnormal T lymphocytes in lpr mice transcribe interferon-gamma and tumor necrosis factor-alpha genes spontaneously in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/10712664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alteration of mitogenic responses of mononuclear cells by anti-ds DNA antibodies resembling immune disorders in patients with systemic lupus erythematosus

1 reference

https://pubmed.ncbi.nlm.nih.gov/10712664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of antibodies to double stranded DNA, purified from serum samples of patients with active systemic lupus erythematosus, on the glomerular mesangial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10712664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cross‐reactions of anti‐DNA autoantibodies with cell surface proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/10712664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polyreactivity is a property of natural and disease-associated human autoantibodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/10712664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autoimmunity and apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/10712664

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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