Synthesis, characterization, and activity of metabolites derived from the cyclooxygenase-2 inhibitor rofecoxib (MK-0966, Vioxx) (Q73324278)

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3 November 2019

title

Synthesis, characterization, and activity of metabolites derived from the cyclooxygenase-2 inhibitor rofecoxib (MK-0966, Vioxx) (English)

1 reference

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3 November 2019

author name string

D A Nicoll-Griffith

1

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3 November 2019

J A Yergey

2

1 reference

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3 November 2019

L A Trimble

3

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3 November 2019

J M Silva

4

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3 November 2019

C Li

5

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3 November 2019

N Chauret

6

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3 November 2019

J Y Gauthier

7

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3 November 2019

E Grimm

8

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3 November 2019

S Léger

9

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3 November 2019

P Roy

10

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3 November 2019

M Thérien

11

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3 November 2019

Z Wang

12

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3 November 2019

P Prasit

13

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3 November 2019

R Zamboni

14

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3 November 2019

R N Young

15

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3 November 2019

C Brideau

16

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3 November 2019

C C Chan

17

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3 November 2019

J Mancini

18

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3 November 2019

D Riendeau

19

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3 November 2019

language of work or name

English

0 references

publication date

1 December 2000

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Bioorganic & Medicinal Chemistry Letters

3 November 2019

published in

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3 November 2019

volume

10

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3 November 2019

issue

23

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3 November 2019

page(s)

2683-2686

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Interpreting the clinical significance of the differential inhibition of cyclooxygenase-1 and cyclooxygenase-2.

3 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1016/S0960-894X(00)00538-2

7 January 2021

The discovery of rofecoxib, [MK 966, Vioxx, 4-(4'-methylsulfonylphenyl)-3-phenyl-2(5H)-furanone], an orally active cyclooxygenase-2-inhibitor

1 reference

https://api.crossref.org/works/10.1016/S0960-894X(00)00538-2

7 January 2021

Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: a full in vitro analysis

1 reference

https://api.crossref.org/works/10.1016/S0960-894X(00)00538-2

7 January 2021

Characterization of rofecoxib as a cyclooxygenase-2 isoform inhibitor and demonstration of analgesia in the dental pain model

1 reference

https://api.crossref.org/works/10.1016/S0960-894X(00)00538-2

7 January 2021

Integrated application of capillary HPLC/continuous-flow liquid secondary ion mass spectrometry to discovery stage metabolism studies

1 reference

https://api.crossref.org/works/10.1016/S0960-894X(00)00538-2

7 January 2021

10.1016/S0960-894X(00)00538-2

Identifiers

DOI

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3 November 2019

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