Bcl-XL protects pancreatic adenocarcinoma cells against CD95- and TRAIL-receptor-mediated apoptosis (Q73292505)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11114725 AND SRC:MED&resulttype=core&format=json

2 November 2019

title

Bcl-XL protects pancreatic adenocarcinoma cells against CD95- and TRAIL-receptor-mediated apoptosis (English)

1 reference

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pancreatic adenocarcinoma

2 November 2019

main subject

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Hinz S

1

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2 November 2019

Trauzold A

2

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2 November 2019

Boenicke L

3

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2 November 2019

Sandberg C

4

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2 November 2019

Beckmann S

5

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2 November 2019

Bayer E

6

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2 November 2019

Walczak H

7

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2 November 2019

Kalthoff H

8

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2 November 2019

Ungefroren H

9

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2 November 2019

language of work or name

English

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publication date

1 November 2000

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2 November 2019

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2 November 2019

volume

19

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2 November 2019

issue

48

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2 November 2019

page(s)

5477-5486

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The role of antiapoptotic Bcl-2 family members in endothelial apoptosis elucidated with antisense oligonucleotides

2 November 2019

cites work

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Ectopic expression of BcI‐2, but not BcI‐xL rescues Ramos B cells from Fas‐mediated apoptosis

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Safety and antitumor activity of recombinant soluble Apo2 ligand

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TRAIL receptor-2 signals apoptosis through FADD and caspase-8

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Bcl-x(L) can inhibit apoptosis in cells that have undergone Fas-induced protease activation

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The Rel/NF-kappaB family directly activates expression of the apoptosis inhibitor Bcl-x(L).

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Moderate activation of the apoptosis inhibitor bcl-xL worsens the prognosis in pancreatic cancer

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TRAIL is a potent inducer of apoptosis in myeloma cells derived from multiple myeloma patients and is not cytotoxic to hematopoietic stem cells

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Caspase cleaved BID targets mitochondria and is required for cytochrome c release, while BCL-XL prevents this release but not tumor necrosis factor-R1/Fas death

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Transduction of human pancreatic tumor cells with vesicular stomatitis virus G-pseudotyped retroviral vectors containing a herpes simplex virus thymidine kinase mutant gene enhances bystander effects and sensitivity to ganciclovir

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Inhibition of death receptor signals by cellular FLIP

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Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand

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Inhibition of Fas-induced apoptosis by Bcl-2.

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Failure of Bcl-2 to block cytochrome c redistribution during TRAIL-induced apoptosis

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Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5.

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The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis

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Over-expression of bcl-xL gene in human gastric adenomas and carcinomas.

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Modulation of apoptosis by endogenous Bcl-xL expression in MKN-45 human gastric cancer cells

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7 January 2021

Interleukin-1 protects transformed keratinocytes from tumor necrosis factor-related apoptosis-inducing ligand- and CD95-induced apoptosis but not from ultraviolet radiation-induced apoptosis

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7 January 2021

Different mechanisms of bone metabolism between patients with stroke and with spinal cord injury

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The proto-oncogene Bcl-2 and its role in regulating apoptosis

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Overexpression of Bcl-x(L) promotes chemotherapy resistance of mammary tumors in a syngeneic mouse model

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A novel receptor for Apo2L/TRAIL contains a truncated death domain

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Immunohistochemical analysis of Bcl-2, Bax, Bcl-X, and Mcl-1 expression in pancreatic cancers

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Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line

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The receptor for the cytotoxic ligand TRAIL

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7 January 2021

An Antagonist Decoy Receptor and a Death Domain-Containing Receptor for TRAIL

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7 January 2021

TRUNDD, a new member of the TRAIL receptor family that antagonizes TRAIL signalling

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7 January 2021

Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family

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Bcl-2 family proteins

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FAP-1: a protein tyrosine phosphatase that associates with Fas

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A caspase-9 variant missing the catalytic site is an endogenous inhibitor of apoptosis

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7 January 2021

FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2

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7 January 2021

Bcl-2 and Fas/APO-1 regulate distinct pathways to lymphocyte apoptosis

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7 January 2021

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7 January 2021

Temperature-sensitive differential affinity of TRAIL for its receptors. DR5 is the highest affinity receptor

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7 January 2021

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