Antibody-directed enzyme prodrug therapy (ADEPT). A three-phase study in ovarian tumor xenografts (Q72208052)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7736526 AND SRC:MED&resulttype=core&format=json

24 October 2019

title

Antibody-directed enzyme prodrug therapy (ADEPT). A three-phase study in ovarian tumor xenografts (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7736526 AND SRC:MED&resulttype=core&format=json

24 October 2019

1 reference

Sharma SK

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7736526 AND SRC:MED&resulttype=core&format=json

24 October 2019

Boden JA

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7736526 AND SRC:MED&resulttype=core&format=json

24 October 2019

Springer CJ

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7736526 AND SRC:MED&resulttype=core&format=json

24 October 2019

Burke PJ

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7736526 AND SRC:MED&resulttype=core&format=json

24 October 2019

Bagshawe KD

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7736526 AND SRC:MED&resulttype=core&format=json

24 October 2019

publication date

1 January 1994

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7736526 AND SRC:MED&resulttype=core&format=json

24 October 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7736526 AND SRC:MED&resulttype=core&format=json

24 October 2019

volume

24-25

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7736526 AND SRC:MED&resulttype=core&format=json

24 October 2019

page(s)

219-228

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7736526 AND SRC:MED&resulttype=core&format=json

Antibody directed enzyme prodrug therapy (ADEPT): a three phase system

24 October 2019

cites work

1 reference

12 December 2020

Inactivation and clearance of an anti-CEA carboxypeptidase G2 conjugate in blood after localisation in a xenograft model

1 reference

12 December 2020

Second antibody clearance of radiolabeled antibody in cancer radioimmunodetection

1 reference

12 December 2020

Improved radioimaging and tumor localization with monoclonal F(ab')2

1 reference

12 December 2020

Radiolabeled fragments of monoclonal antibodies against carcinoembryonic antigen for localization of human colon carcinoma grafted into nude mice

1 reference

12 December 2020

Third Gordon Hamilton-Fairley Memorial Lecture. Tumour markers—Where do we go from here?

1 reference

12 December 2020

Antibody-guided radiolocalisation of tumours in patients with testicular or ovarian cancer using two radioiodinated monoclonal antibodies to placental alkaline phosphatase

1 reference

12 December 2020

Reactivity of a monoclonal antibody with human ovarian carcinoma

1 reference

12 December 2020

Carbohydrate-mediated clearance of immune complexes from the circulation. A role for galactose residues in the hepatic uptake of IgG-antigen complexes.

1 reference

12 December 2020

Relationship between antigen density and immunotherapeutic response elicited by monoclonal antibodies against solid tumors.

1 reference

12 December 2020

Use of second antibody in radioimmunotherapy

1 reference

12 December 2020

Molecular and functional characterisation of a fusion protein suited for tumour specific prodrug activation

1 reference

12 December 2020

Purification and properties of carboxypeptidase G2 from Pseudomonas sp. strain RS-16. Use of a novel triazine dye affinity method

1 reference

12 December 2020

Antibody directed enzyme prodrug therapy (ADEPT): clinical report

1 reference

12 December 2020

Anti-tumor effects of antibody-alkaline phosphatase conjugates in combination with etoposide phosphate

1 reference

12 December 2020

Novel prodrugs which are activated to cytotoxic alkylating agents by carboxypeptidase G2

1 reference

12 December 2020

An immunohistological study of testicular germ cell tumours using two different monoclonal antibodies against placental alkaline phosphatase

1 reference

12 December 2020

Specific activation of glucuronide prodrugs by antibody-targeted enzyme conjugates for cancer therapy

1 reference

12 December 2020

Limitations of radiolabeled monoclonal antibodies for localization of human neoplasms

1 reference

12 December 2020

Enhancement of the in vitro and in vivo antitumor activities of phosphorylated mitomycin C and etoposide derivatives by monoclonal antibody-alkaline phosphatase conjugates

1 reference

12 December 2020

The First Bagshawe lecture. Towards generating cytotoxic agents at cancer sites

1 reference

12 December 2020

A cytotoxic agent can be generated selectively at cancer sites

1 reference

12 December 2020

Antibody directed enzymes revive anti-cancer prodrugs concept

1 reference

12 December 2020

Optimisation of small-scale coupling of A5B7 monoclonal antibody to carboxypeptidase G2

1 reference

12 December 2020

Biodistribution of antibodies after intraperitoneal or intravenous injection and effect of carbohydrate modifications

1 reference

12 December 2020

Ablation of human choriocarcinoma xenografts in nude mice by antibody-directed enzyme prodrug therapy (ADEPT) with three novel compounds

1 reference

12 December 2020

Human immune response to monoclonal antibody-enzyme conjugates in ADEPT pilot clinical trial

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF02789232

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7736526 AND SRC:MED&resulttype=core&format=json

24 October 2019

1 reference