Peripheral re-localization of constitutive heterochromatin advances its replication timing and impairs maintenance of silencing marks. (Q64949466)

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26 March 2020

title

Peripheral re-localization of constitutive heterochromatin advances its replication timing and impairs maintenance of silencing marks (English)

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26 March 2020

7

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26 March 2020

author name string

Kathrin S Heinz

1

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26 March 2020

Corella S Casas-Delucchi

2

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Timea Török

3

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Dusan Cmarko

4

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Alexander Rapp

5

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Ivan Raska

6

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26 March 2020

language of work or name

English

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publication date

1 July 2018

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26 March 2020

number of pages

17

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inferred from page(s)

published in

Nucleic Acids Research

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volume

46

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issue

12

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26 March 2020

page(s)

6112-6128

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Creative Commons Attribution-NonCommercial 4.0 International

26 March 2020

copyright license

start time

10 May 2018

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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describes a project that uses

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6158597/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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12 December 2020

Dynamic organization of DNA replication in mammalian cell nuclei: spatially and temporally defined replication of chromosome-specific alpha-satellite DNA sequences

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Spatial and temporal distribution of DNA replication sites localized by immunofluorescence and confocal microscopy in mouse fibroblasts

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Mouse major (gamma) satellite DNA is highly conserved and organized into extremely long tandem arrays: implications for recombination between nonhomologous chromosomes

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Structural organizations of replicon domains during DNA synthetic phase in the mammalian nucleus

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Chromosomal and Nuclear Location of Mouse Satellite DNA in Individual Cells

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Cell cycle-dependent establishment of a late replication program

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Replicon clusters are stable units of chromosome structure: evidence that nuclear organization contributes to the efficient activation and propagation of S phase in human cells

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The spatial position and replication timing of chromosomal domains are both established in early G1 phase

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Making sense of eukaryotic DNA replication origins

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Loss of the Suv39h histone methyltransferases impairs mammalian heterochromatin and genome stability

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Histone acetylation regulates the time of replication origin firing

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DNA polymerase clamp shows little turnover at established replication sites but sequential de novo assembly at adjacent origin clusters

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The histone deacetylase inhibitor trichostatin A alters the pattern of DNA replication origin activity in human cells

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Methyl CpG-binding proteins induce large-scale chromatin reorganization during terminal differentiation

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PCNA acts as a stationary loading platform for transiently interacting Okazaki fragment maturation proteins

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Uncoupling global and fine-tuning replication timing determinants for mouse pericentric heterochromatin

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Chromatin state marks cell-type- and gender-specific replication of the Drosophila genome

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Modulation of protein properties in living cells using nanobodies

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Early initiation of a replication origin tethered at the nuclear periphery

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Histone acetylation controls the inactive X chromosome replication dynamics

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Genome-scale analysis of metazoan replication origins reveals their organization in specific but flexible sites defined by conserved features

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Histone hypoacetylation is required to maintain late replication timing of constitutive heterochromatin.

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Epigenetic control of DNA replication dynamics in mammals.

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New image colocalization coefficient for fluorescence microscopy to quantify (bio-)molecular interactions.

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DNA replication timing

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Peaks cloaked in the mist: the landscape of mammalian replication origins

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3D replicon distributions arise from stochastic initiation and domino-like DNA replication progression.

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12 December 2020

Identifiers

DOI

10.1093/NAR/GKY368

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29750270 AND SRC:MED&resulttype=core&format=json

26 March 2020

1 reference

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26 March 2020

PubMed publication ID

29750270

1 reference