Creation of versatile cloning platforms for transgene expression and dCas9-based epigenome editing (Q64375251)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30590691 AND SRC:MED&resulttype=core&format=json

16 April 2020

title

Creation of versatile cloning platforms for transgene expression and dCas9-based epigenome editing (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30590691 AND SRC:MED&resulttype=core&format=json

16 April 2020

1

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16 April 2020

Christopher B Newgard

7

object named as

Christopher B Newgard

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16 April 2020

author name string

Amanda E Conway

2

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16 April 2020

Michelle E Arlotto

3

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16 April 2020

Dorothy H Slentz

4

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16 April 2020

Deborah M Muoio

5

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16 April 2020

Thomas C Becker

6

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16 April 2020

language of work or name

English

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publication date

1 February 2019

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16 April 2020

published in

Nucleic Acids Research

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volume

47

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issue

4

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16 April 2020

page(s)

e23

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Creative Commons Attribution 4.0 International

16 April 2020

copyright license

start time

28 December 2018

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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An adenovirus vector for efficient RNA interference-mediated suppression of target genes in insulinoma cells and pancreatic islets of langerhans

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The Nkx6.1 homeodomain transcription factor suppresses glucagon expression and regulates glucose-stimulated insulin secretion in islet beta cells

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Mechanisms of pancreatic beta-cell death in type 1 and type 2 diabetes: many differences, few similarities

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A pyruvate cycling pathway involving cytosolic NADP-dependent isocitrate dehydrogenase regulates glucose-stimulated insulin secretion

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pdx-1 function is specifically required in embryonic beta cells to generate appropriate numbers of endocrine cell types and maintain glucose homeostasis

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Stimulation of human and rat islet beta-cell proliferation with retention of function by the homeodomain transcription factor Nkx6.1

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A one pot, one step, precision cloning method with high throughput capability

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Enzymatic assembly of DNA molecules up to several hundred kilobases

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12 December 2020

Molecular evolution of a novel hyperactive Sleeping Beauty transposase enables robust stable gene transfer in vertebrates

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12 December 2020

A novel hypomorphic PDX1 mutation responsible for permanent neonatal diabetes with subclinical exocrine deficiency

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Contamination with E1A-positive wild-type adenovirus accounts for species-specific stimulation of islet cell proliferation by CCK: a cautionary note.

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Robust cardiomyocyte-specific gene expression following systemic injection of AAV: in vivo gene delivery follows a Poisson distribution

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Histone H3K27ac separates active from poised enhancers and predicts developmental state

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A hyperactive piggyBac transposase for mammalian applications

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Circular polymerase extension cloning for high-throughput cloning of complex and combinatorial DNA libraries

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High Cleavage Efficiency of a 2A Peptide Derived from Porcine Teschovirus-1 in Human Cell Lines, Zebrafish and Mice

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CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes

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Pdx-1 activates islet α- and β-cell proliferation via a mechanism regulated by transient receptor potential cation channels 3 and 6 and extracellular signal-regulated kinases 1 and 2.

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12 December 2020

Locus-specific editing of histone modifications at endogenous enhancers

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12 December 2020

Super-enhancers in the control of cell identity and disease

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12 December 2020

Chromatin stretch enhancer states drive cell-specific gene regulation and harbor human disease risk variants

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12 December 2020

DNASU plasmid and PSI:Biology-Materials repositories: resources to accelerate biological research.

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Pdx1 maintains β cell identity and function by repressing an α cell program

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12 December 2020

Nkx6.1 regulates islet β-cell proliferation via Nr4a1 and Nr4a3 nuclear receptors

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12 December 2020

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Genome Editing with CRISPR-Cas9: Can It Get Any Better?

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Comparison of Cas9 activators in multiple species

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Evaluation of off-target and on-target scoring algorithms and integration into the guide RNA selection tool CRISPOR.

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A Pdx-1-Regulated Soluble Factor Activates Rat and Human Islet Cell Proliferation.

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Identifiers

DOI

10.1093/NAR/GKY1286

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30590691 AND SRC:MED&resulttype=core&format=json

16 April 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30590691 AND SRC:MED&resulttype=core&format=json

16 April 2020

PubMed publication ID

30590691

1 reference