Elevated VMP1 expression in acute myeloid leukemia amplifies autophagy and is protective against venetoclax-induced apoptosis (Q64290693)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31142733 AND SRC:MED&resulttype=core&format=json

29 April 2020

title

Elevated VMP1 expression in acute myeloid leukemia amplifies autophagy and is protective against venetoclax-induced apoptosis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31142733 AND SRC:MED&resulttype=core&format=json

29 April 2020

0 references

1 reference

1 reference

acute myeloid leukemia

1 reference

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31142733 AND SRC:MED&resulttype=core&format=json

29 April 2020

Jan Jacob Schuringa

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31142733 AND SRC:MED&resulttype=core&format=json

29 April 2020

author name string

Hendrik Folkerts

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31142733 AND SRC:MED&resulttype=core&format=json

29 April 2020

Albertus T Wierenga

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31142733 AND SRC:MED&resulttype=core&format=json

29 April 2020

Fiona A van den Heuvel

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31142733 AND SRC:MED&resulttype=core&format=json

29 April 2020

Darlyne S Kluit

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31142733 AND SRC:MED&resulttype=core&format=json

29 April 2020

Jennifer Jaques

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31142733 AND SRC:MED&resulttype=core&format=json

29 April 2020

Edo Vellenga

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31142733 AND SRC:MED&resulttype=core&format=json

29 April 2020

language of work or name

English

0 references

publication date

29 May 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31142733 AND SRC:MED&resulttype=core&format=json

29 April 2020

published in

Cell Death and Disease

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31142733 AND SRC:MED&resulttype=core&format=json

29 April 2020

volume

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31142733 AND SRC:MED&resulttype=core&format=json

29 April 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31142733 AND SRC:MED&resulttype=core&format=json

29 April 2020

page(s)

421

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31142733 AND SRC:MED&resulttype=core&format=json

describes a project that uses

29 April 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6541608/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Mitochondrial accumulation under oxidative stress is due to defects in autophagy.

1 reference

https://api.crossref.org/works/10.1038/S41419-019-1648-4

7 January 2021

Mitophagy in hematopoietic stem cells: the case for exploration

1 reference

https://api.crossref.org/works/10.1038/S41419-019-1648-4

7 January 2021

Eaten alive: a history of macroautophagy

1 reference

https://api.crossref.org/works/10.1038/S41419-019-1648-4

7 January 2021

Autophagy is required for stem cell mobilization by G-CSF.

1 reference

https://api.crossref.org/works/10.1038/S41419-019-1648-4

7 January 2021

Autophagy maintains the metabolism and function of young and old stem cells.

1 reference

https://api.crossref.org/works/10.1038/S41419-019-1648-4

7 January 2021

Autophagy Proteins ATG5 and ATG7 Are Essential for the Maintenance of Human CD34( ) Hematopoietic Stem-Progenitor Cells

1 reference

https://api.crossref.org/works/10.1038/S41419-019-1648-4

7 January 2021

Induction of autophagy is essential for monocyte-macrophage differentiation

1 reference

https://api.crossref.org/works/10.1038/S41419-019-1648-4

7 January 2021

Ulk1 plays a critical role in the autophagic clearance of mitochondria and ribosomes during reticulocyte maturation

1 reference

https://api.crossref.org/works/10.1038/S41419-019-1648-4

7 January 2021

Autophagy facilitates organelle clearance during differentiation of human erythroblasts: evidence for a role for ATG4 paralogs during autophagosome maturation.

1 reference

https://api.crossref.org/works/10.1038/S41419-019-1648-4

7 January 2021

Mitochondrial clearance is regulated by Atg7-dependent and -independent mechanisms during reticulocyte maturation

1 reference

https://api.crossref.org/works/10.1038/S41419-019-1648-4

7 January 2021

Inhibition of autophagy as a treatment strategy for p53 wild-type acute myeloid leukemia

1 reference

https://api.crossref.org/works/10.1038/S41419-019-1648-4

7 January 2021

Caspase-3 controls AML1-ETO-driven leukemogenesis via autophagy modulation in a ULK1-dependent manner

1 reference

https://api.crossref.org/works/10.1038/S41419-019-1648-4

7 January 2021

RET-mediated autophagy suppression as targetable co-dependence in acute myeloid leukemia.

1 reference

https://api.crossref.org/works/10.1038/S41419-019-1648-4

7 January 2021

Autophagy, a key mechanism of oncogenesis and resistance in leukemia

1 reference

https://api.crossref.org/works/10.1038/S41419-019-1648-4

7 January 2021

Atg7 suppression enhances chemotherapeutic agent sensitivity and overcomes stroma-mediated chemoresistance in acute myeloid leukemia

1 reference

https://api.crossref.org/works/10.1038/S41419-019-1648-4

7 January 2021

Cytoprotective autophagy maintains leukemia-initiating cells in murine myeloid leukemia.

1 reference

https://api.crossref.org/works/10.1038/S41419-019-1648-4

7 January 2021

Histone deacetylase inhibitors induce apoptosis in myeloid leukemia by suppressing autophagy

1 reference

https://api.crossref.org/works/10.1038/S41419-019-1648-4

7 January 2021

Autophagy is a survival mechanism of acute myelogenous leukemia precursors during dual mTORC2/mTORC1 targeting

1 reference

https://api.crossref.org/works/10.1038/S41419-019-1648-4

7 January 2021

Complete mutational spectrum of the autophagy interactome: a novel class of tumor suppressor genes in myeloid neoplasms.

1 reference

https://api.crossref.org/works/10.1038/S41419-019-1648-4

7 January 2021

Atg5-dependent autophagy contributes to the development of acute myeloid leukemia in an MLL-AF9-driven mouse model

1 reference

https://api.crossref.org/works/10.1038/S41419-019-1648-4

7 January 2021

The ER-Localized Transmembrane Protein EPG-3/VMP1 Regulates SERCA Activity to Control ER-Isolation Membrane Contacts for Autophagosome Formation.

1 reference

https://api.crossref.org/works/10.1038/S41419-019-1648-4

7 January 2021

ER-plasma membrane contact sites contribute to autophagosome biogenesis by regulation of local PI3P synthesis

1 reference

https://api.crossref.org/works/10.1038/S41419-019-1648-4

7 January 2021

VMP1 is a new player in the regulation of the autophagy-specific phosphatidylinositol 3-kinase complex activation

1 reference

https://api.crossref.org/works/10.1038/S41419-019-1648-4

7 January 2021

Differential interactions between Beclin 1 and Bcl-2 family members

1 reference

https://api.crossref.org/works/10.1038/S41419-019-1648-4

7 January 2021

Novel roles of Vmp1: inhibition metastasis and proliferation of hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1038/S41419-019-1648-4

7 January 2021

The pancreatitis-induced vacuole membrane protein 1 triggers autophagy in mammalian cells

1 reference

https://api.crossref.org/works/10.1038/S41419-019-1648-4

7 January 2021

PCR based determination of mitochondrial DNA copy number in multiple species

1 reference

https://api.crossref.org/works/10.1038/S41419-019-1648-4

7 January 2021

High VEGFC expression is associated with unique gene expression profiles and predicts adverse prognosis in pediatric and adult acute myeloid leukemia.

1 reference

https://api.crossref.org/works/10.1038/S41419-019-1648-4

7 January 2021

Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia

1 reference

https://api.crossref.org/works/10.1038/S41419-019-1648-4

7 January 2021

Increased peripheral platelet destruction and caspase-3-independent programmed cell death of bone marrow megakaryocytes in myelodysplastic patients.

1 reference

https://api.crossref.org/works/10.1038/S41419-019-1648-4

7 January 2021

Immunocytochemical localization of the 27K beta-crystallin polypeptide in the mouse lens during development using a specific monoclonal antibody: implications for cataract formation in the Philly mouse

1 reference

https://api.crossref.org/works/10.1038/S41419-019-1648-4

7 January 2021

BloodSpot: a database of gene expression profiles and transcriptional programs for healthy and malignant haematopoiesis

1 reference

https://api.crossref.org/works/10.1038/S41419-019-1648-4

7 January 2021

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

1 reference

https://api.crossref.org/works/10.1038/S41419-019-1648-4

7 January 2021

VMP1 Establishes ER-Microdomains that Regulate Membrane Contact Sites and Autophagy

1 reference

https://api.crossref.org/works/10.1038/S41419-019-1648-4

7 January 2021

Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy.

1 reference

https://api.crossref.org/works/10.1038/S41419-019-1648-4

7 January 2021

The VMP1-Beclin 1 interaction regulates autophagy induction

1 reference

https://api.crossref.org/works/10.1038/S41419-019-1648-4

7 January 2021

High Throughput Screens to Identify Autophagy Inducers that Function by Disrupting Beclin 1/Bcl-2 Binding.

1 reference

https://api.crossref.org/works/10.1038/S41419-019-1648-4

7 January 2021

Acquired resistance to venetoclax (ABT-199) in t(14;18) positive lymphoma cells

1 reference

https://api.crossref.org/works/10.1038/S41419-019-1648-4

7 January 2021

The MCL1 inhibitor S63845 is tolerable and effective in diverse cancer models

1 reference

https://api.crossref.org/works/10.1038/S41419-019-1648-4

7 January 2021

1 reference

https://api.crossref.org/works/10.1038/S41419-019-1648-4

7 January 2021

The pancreatitis-associated protein VMP1, a key regulator of inducible autophagy, promotes Kras(G12D)-mediated pancreatic cancer initiation.

1 reference

https://api.crossref.org/works/10.1038/S41419-019-1648-4

7 January 2021

The autophagy protein Atg7 is essential for hematopoietic stem cell maintenance

1 reference

https://api.crossref.org/works/10.1038/S41419-019-1648-4

7 January 2021

Identification of Atg5-dependent transcriptional changes and increases in mitochondrial mass in Atg5-deficient T lymphocytes.

1 reference

https://api.crossref.org/works/10.1038/S41419-019-1648-4

7 January 2021

Neural-specific deletion of FIP200 leads to cerebellar degeneration caused by increased neuronal death and axon degeneration

1 reference

https://api.crossref.org/works/10.1038/S41419-019-1648-4

7 January 2021

Hypoxia-induced autophagy is mediated through hypoxia-inducible factor induction of BNIP3 and BNIP3L via their BH3 domains

1 reference

https://api.crossref.org/works/10.1038/S41419-019-1648-4

7 January 2021

A novel HIF-1α/VMP1-autophagic pathway induces resistance to photodynamic therapy in colon cancer cells

1 reference

https://api.crossref.org/works/10.1038/S41419-019-1648-4

7 January 2021

The rise of apoptosis: targeting apoptosis in hematologic malignancies

1 reference

https://api.crossref.org/works/10.1038/S41419-019-1648-4

7 January 2021

The TAK1-NF-κB axis as therapeutic target for AML.

1 reference

https://api.crossref.org/works/10.1038/S41419-019-1648-4

7 January 2021

Blockade of BCL-2 proteins efficiently induces apoptosis in progenitor cells of high-risk myelodysplastic syndromes patients.

1 reference

https://api.crossref.org/works/10.1038/S41419-019-1648-4

7 January 2021

Overexpression of Bcl2 protein predicts chemoresistance in acute myeloid leukemia: its correlation with FLT3.

1 reference

https://api.crossref.org/works/10.1038/S41419-019-1648-4

7 January 2021

Venetoclax and low-dose cytarabine induced complete remission in a patient with high-risk acute myeloid leukemia: a case report

1 reference

https://api.crossref.org/works/10.1038/S41419-019-1648-4

7 January 2021

Selective BCL-2 inhibition by ABT-199 causes on-target cell death in acute myeloid leukemia

1 reference

https://api.crossref.org/works/10.1038/S41419-019-1648-4

7 January 2021

Efficacy and Biological Correlates of Response in a Phase II Study of Venetoclax Monotherapy in Patients with Acute Myelogenous Leukemia

1 reference

https://api.crossref.org/works/10.1038/S41419-019-1648-4

7 January 2021

AML cells have low spare reserve capacity in their respiratory chain that renders them susceptible to oxidative metabolic stress

1 reference

https://api.crossref.org/works/10.1038/S41419-019-1648-4

7 January 2021

Mitochondrial levels determine variability in cell death by modulating apoptotic gene expression.

1 reference

https://api.crossref.org/works/10.1038/S41419-019-1648-4

7 January 2021

10.1038/S41419-019-1648-4

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31142733 AND SRC:MED&resulttype=core&format=json

29 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31142733 AND SRC:MED&resulttype=core&format=json

29 April 2020

PubMed publication ID

31142733

1 reference