Fibrinogen αC domain: Its importance in physiopathology (Q64228855)

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Sam Qiumars Mirshahi

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Remi Varin

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Linda L Pritchard

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Claudine Soria

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Massoud Mirshahi

Research and Practice in Thrombosis and Haemostasis

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language of work or name

English

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publication date

April 2019

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published in

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volume

3

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issue

2

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page(s)

173-183

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cites work

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alpha-fibrinogen Thr312Ala polymorphism and venous thromboembolism.

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Aberrant fibrin formation and cross-linking of fibrinogen Nieuwegein, a variant with a shortened Aalpha-chain, alters endothelial capillary tube formation

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Receptors that mediate cellular dependence

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Fibrinogen and fibrin structure and functions

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Hereditary amyloidosis in early childhood associated with a novel insertion-deletion (indel) in the fibrinogen Aalpha chain gene.

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Fibrinogen Guarenas, an abnormal fibrinogen with an Aalpha-chain truncation due to a nonsense mutation at Aalpha 467 Glu (GAA)-->stop (TAA)

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Modification of fibrinogen by homocysteine thiolactone increases resistance to fibrinolysis: a potential mechanism of the thrombotic tendency in hyperhomocysteinemia

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A novel fibrinogen variant (fibrinogen Seoul II; AalphaGln328Pro) characterized by impaired fibrin alpha-chain cross-linking.

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The association of alpha-fibrinogen Thr312Ala polymorphism and venous thromboembolism in the LITE study

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Direct evidence for specific interactions of the fibrinogen alphaC-domains with the central E region and with each other.

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Fibrin deposition accelerates neurovascular damage and neuroinflammation in mouse models of Alzheimer's disease

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Structural analyses of fibrinogen amyloid fibrils

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Clinical and biological features of 3 cases of hypofibrinogenemia associated with three different mutations (gamma Ala341Thr, Bbeta Tyr326Cys and Aalpha Asp496Asn)

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Capillary cerebral amyloid angiopathy is associated with vessel occlusion and cerebral blood flow disturbances

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A new electrophoretic variant of fibrinogen associated with venous thromboembolism, fibrinogen Bordeaux Aalpha Arg439-->Cys

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Evidence that alpha2-antiplasmin becomes covalently ligated to plasma fibrinogen in the circulation: a new role for plasma factor XIII in fibrinolysis regulation

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Recommendations for nomenclature on fibrinogen and fibrin.

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Diagnosis, pathogenesis, treatment, and prognosis of hereditary fibrinogen A alpha-chain amyloidosis

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12 December 2020

Amyloid fibrils: abnormal protein assembly

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Hypodysfibrinogenemia causing mild bleeding and thrombotic complications in a compound heterozygote of AalphaIVS4 1G>T mutation and Aalpha4841delC truncation (Aalpha(Perth)).

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High prevalence of dysfibrinogenemia among patients with chronic thromboembolic pulmonary hypertension

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12 December 2020

Demonstration of heterodimeric fibrinogen molecules partially conjugated with albumin in a novel dysfibrinogen: fibrinogen Mannheim V.

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12 December 2020

Fibrinogen, a possible key player in Alzheimer's disease

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Hereditary fibrinogen A alpha-chain amyloidosis: phenotypic characterization of a systemic disease and the role of liver transplantation.

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Fibrinogen and beta-amyloid association alters thrombosis and fibrinolysis: a possible contributing factor to Alzheimer's disease

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Tau in Alzheimer disease and related tauopathies

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Noncovalent Interaction of α2-Antiplasmin with Fibrin(ogen): Localization of α2-Antiplasmin-Binding Sites

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Alzheimer's disease peptide beta-amyloid interacts with fibrinogen and induces its oligomerization.

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Identification of respective lysine donor and glutamine acceptor sites involved in factor XIIIa-catalyzed fibrin α chain cross-linking

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Aβ delays fibrin clot lysis by altering fibrin structure and attenuating plasminogen binding to fibrin.

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12 December 2020

On the mechanism of αC polymer formation in fibrin.

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Fibrinogen and altered hemostasis in Alzheimer's disease

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12 December 2020

Mechanisms of fibrin polymerization and clinical implications

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12 December 2020

Molecular basis of quantitative fibrinogen disorders in 27 patients from India

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12 December 2020

Fibrinogen Aα Thr312Ala polymorphism specifically contributes to chronic thromboembolic pulmonary hypertension by increasing fibrin resistance

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12 December 2020

Dusart Syndrome in a Scandinavian family characterized by arterial and venous thrombosis at young age.

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12 December 2020

Partial deletion of the αC-domain in the Fibrinogen Perth variant is associated with thrombosis, increased clot strength and delayed fibrinolysis

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The effect of blood coagulation factor XIII on fibrin clot structure and fibrinolysis.

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Fibrinogen Dusart presenting as recurrent thromboses in the hepatic portal system

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A novel Aβ-fibrinogen interaction inhibitor rescues altered thrombosis and cognitive decline in Alzheimer's disease mice

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12 December 2020

Fibrin deposited in the Alzheimer's disease brain promotes neuronal degeneration

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12 December 2020

Novel heterozygous dysfibrinogenemia, Sumida (AαC472S), showed markedly impaired lateral aggregation of protofibrils and mildly lower functional fibrinogen levels

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12 December 2020

Assessing fibrinogen extravasation into Alzheimer's disease brain using high-content screening of brain tissue microarrays.

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12 December 2020

The Alzheimer's disease peptide β-amyloid promotes thrombin generation through activation of coagulation factor XII.

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12 December 2020

Biochemical and structural analysis of the interaction between β-amyloid and fibrinogen.

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Interactions of β-amyloid peptide with fibrinogen and coagulation factor XII may contribute to Alzheimer's disease

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Alzheimer's Disease Can Be Spared by Nonsteroidal Anti-Inflammatory Drugs

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12 December 2020

Renal Amyloidosis Associated With 5 Novel Variants in the Fibrinogen A Alpha Chain Protein

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12 December 2020

Blood-brain barrier breakdown in Alzheimer disease and other neurodegenerative disorders

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12 December 2020