MuSK myasthenia gravis monoclonal antibodies: Valency dictates pathogenicity (Q64120772)

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29 April 2020

title

MuSK myasthenia gravis monoclonal antibodies: Valency dictates pathogenicity (English)

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29 April 2020

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Silvère M van der Maarel

9

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29 April 2020

Jan J Verschuuren

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29 April 2020

author name string

Maartje G Huijbers

1

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29 April 2020

Dana L Vergoossen

2

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29 April 2020

Yvonne E Fillié-Grijpma

3

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29 April 2020

Inge E van Es

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29 April 2020

Marvyn T Koning

5

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29 April 2020

Linda M Slot

6

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29 April 2020

Hendrik Veelken

7

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29 April 2020

Jaap J Plomp

8

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29 April 2020

language of work or name

English

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publication date

21 February 2019

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Neurology(R) neuroimmunology & neuroinflammation

29 April 2020

published in

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volume

6

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issue

3

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page(s)

e547

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describes a project that uses

29 April 2020

ImageJ

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11 June 2022

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inferred from PubMed Central ID database lookup

cites work

Direct demonstration of MuSK involvement in acetylcholine receptor clustering through identification of agonist ScFv

1 reference

12 December 2020

Dimerization of the muscle-specific kinase induces tyrosine phosphorylation of acetylcholine receptors and their aggregation on the surface of myotubes

1 reference

12 December 2020

The juxtamembrane region of MuSK has a critical role in agrin-mediated signaling

1 reference

12 December 2020

Auto-antibodies to the receptor tyrosine kinase MuSK in patients with myasthenia gravis without acetylcholine receptor antibodies

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12 December 2020

Detection and characterization of MuSK antibodies in seronegative myasthenia gravis

1 reference

12 December 2020

Acetylcholine receptors loss and postsynaptic damage in MuSK antibody-positive myasthenia gravis

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12 December 2020

Genetic and functional characterization of human pemphigus vulgaris monoclonal autoantibodies isolated by phage display

1 reference

12 December 2020

Anti-MuSK antibodies: correlation with myasthenia gravis severity

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12 December 2020

Clinical and experimental features of MuSK antibody positive MG in Japan

1 reference

12 December 2020

Anti-Inflammatory Activity of Human IgG4 Antibodies by Dynamic Fab Arm Exchange

1 reference

12 December 2020

Patient autoantibodies deplete postsynaptic muscle-specific kinase leading to disassembly of the ACh receptor scaffold and myasthenia gravis in mice.

1 reference

12 December 2020

Anti-MuSK autoantibodies block binding of collagen Q to MuSK

1 reference

12 December 2020

Divalent and monovalent autoantibodies cause dysfunction of MuSK by distinct mechanisms in a rabbit model of myasthenia gravis

1 reference

12 December 2020

Muscle-specific kinase myasthenia gravis IgG4 autoantibodies cause severe neuromuscular junction dysfunction in mice

1 reference

12 December 2020

Pemphigus autoantibodies generated through somatic mutations target the desmoglein-3 cis-interface.

1 reference

12 December 2020

Antibodies against Wnt receptor of muscle-specific tyrosine kinase in myasthenia gravis

1 reference

12 December 2020

Phenotypic differences between IgG4 and IgG1 B cells point to distinct regulation of the IgG4 response.

1 reference

12 December 2020

MuSK myasthenia gravis IgG4 disrupts the interaction of LRP4 with MuSK but both IgG4 and IgG1-3 can disperse preformed agrin-independent AChR clusters

1 reference

12 December 2020

MuSK IgG4 autoantibodies cause myasthenia gravis by inhibiting binding between MuSK and Lrp4.

1 reference

12 December 2020

The expanding field of IgG4-mediated neurological autoimmune disorders

1 reference

12 December 2020

Collagen Q and anti-MuSK autoantibody competitively suppress agrin/LRP4/MuSK signaling

1 reference

12 December 2020

Longitudinal epitope mapping in MuSK myasthenia gravis: implications for disease severity.

1 reference

12 December 2020

ARTISAN PCR: rapid identification of full-length immunoglobulin rearrangements without primer binding bias.

1 reference

12 December 2020

The Immunobiology of Immunoglobulin G4.

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12 December 2020

IgG4 autoantibodies against muscle-specific kinase undergo Fab-arm exchange in myasthenia gravis patients

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12 December 2020

Dysregulation of B Cell Repertoire Formation in Myasthenia Gravis Patients Revealed through Deep Sequencing.

1 reference

12 December 2020

Autoantibody-producing plasmablasts after B cell depletion identified in muscle-specific kinase myasthenia gravis

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12 December 2020

IgG4-mediated autoimmune diseases: a niche of antibody-mediated disorders.

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12 December 2020

Fundamental Molecules and Mechanisms for Forming and Maintaining Neuromuscular Synapses.

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12 December 2020

Preserving neuromuscular synapses in ALS by stimulating MuSK with a therapeutic agonist antibody.

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12 December 2020

A New Classification System for IgG4 Autoantibodies

1 reference

12 December 2020

Variable Domain N-Linked Glycans Acquired During Antigen-Specific Immune Responses Can Contribute to Immunoglobulin G Antibody Stability.

1 reference

12 December 2020

10.1212/NXI.0000000000000547

Identifiers

DOI

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29 April 2020

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29 April 2020

PubMed publication ID

30882021

1 reference