Challenges in Translating from Bench to Bed-Side: Pro-Angiogenic Peptides for Ischemia Treatment (Q64108288)

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Challenges in Translating from Bench to Bed-Side: Pro-Angiogenic Peptides for Ischemia Treatment (English)

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translational medical research

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Siyu Shi

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Vivek A. Kumar

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Karel Petrak

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Zain Siddiqui

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Ka Kyung Kim

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Biplab Sarkar

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English

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28 March 2019

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Therapeutic angiogenesis

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Vascular Effects of FGF-2 and VEGF-B in Rabbits with Bilateral Hind Limb Ischemia

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MicroRNA-92a controls angiogenesis and functional recovery of ischemic tissues in mice

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Fibrillogenesis in continuously spun synthetic collagen fiber

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Increased perfusion and angiogenesis in a hindlimb ischemia model with plasmid FGF-2 delivered by noninvasive electroporation

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Randomized, double-blind, placebo-controlled clinical trial of hepatocyte growth factor plasmid for critical limb ischemia

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Microcrimped collagen fiber-elastin composites.

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Safety and efficacy of patient specific intramuscular injection of HGF plasmid gene therapy on limb perfusion and wound healing in patients with ischemic lower extremity ulceration: Results of the HGF-0205 trial

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Cell surface engineering with polyelectrolyte multilayer thin films.

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Elastin-like protein matrix reinforced with collagen microfibers for soft tissue repair.

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Effect of fibroblast growth factor NV1FGF on amputation and death: a randomised placebo-controlled trial of gene therapy in critical limb ischaemia

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Safety of vascular endothelial and hepatocyte growth factor gene therapy in patients with critical limb ischemia

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Pharmacokinetics and pharmacodynamics of VEGF-neutralizing antibodies

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MEMS-assisted spatially homogeneous endothelialization of a high length-to-depth aspect ratio microvascular network

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Functional and pharmacological characterization of a VEGF mimetic peptide on reparative angiogenesis.

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A biologically active surface enzyme assembly that attenuates thrombus formation.

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Acellular vascular grafts generated from collagen and elastin analogs

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Vascular endothelial growth factor in heart failure

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Microablation of collagen-based substrates for soft tissue engineering

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Bidirectional crosstalk between periventricular endothelial cells and neural progenitor cells promotes the formation of a neurovascular unit.

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Exercise for intermittent claudication

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Overview of pharmacokinetics.

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Two-step self-assembly of liposome-multidomain peptide nanofiber hydrogel for time-controlled release.

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Highly angiogenic peptide nanofibers

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pCMV-vegf165 Intramuscular Gene Transfer is an Effective Method of Treatment for Patients With Chronic Lower Limb Ischemia

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Self-assembling multidomain peptides tailor biological responses through biphasic release.

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Drug-triggered and cross-linked self-assembling nanofibrous hydrogels.

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A compendium on peripheral arterial disease

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Identification and characterization of VEGF-A-responsive neutrophils expressing CD49d, VEGFR1, and CXCR4 in mice and humans

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Safety and efficacy of plasmid DNA expressing two isoforms of hepatocyte growth factor in patients with critical limb ischemia

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Functional characterization of a VEGF-A-targeting Anticalin, prototype of a novel therapeutic human protein class

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Evaluation of the clinical relevance and limitations of current pre-clinical models of peripheral artery disease

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Nanofibrous Snake Venom Hemostat

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Controlled Angiogenesis in Peptide Nanofiber Composite Hydrogels

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Rational design of fiber forming supramolecular structures

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Treatment of hind limb ischemia using angiogenic peptide nanofibers

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A new algorithm for a better characterization and timing of the anti-VEGF vascular effect named "normalization".

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Results of an International Postmarketing Surveillance Study of pl-VEGF165 Safety and Efficacy in 210 Patients with Peripheral Arterial Disease

1 reference

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Therapeutic Angiogenesis With Intramuscular NV1FGF Improves Amputation-free Survival in Patients With Critical Limb Ischemia

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Self-Assembling Multidomain Peptide Nanofibers for Delivery of Bioactive Molecules and Tissue Regeneration

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Functional Characterization of VEGF- and FGF-induced Tumor Blood Vessel Models in Human Cancer Xenografts

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Development of peptide inhibitors of HIV transmission.

1 reference

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Self-Assembly of a Dentinogenic Peptide Hydrogel.

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Angiogenic Self-Assembling Peptide Scaffolds for Functional Tissue Regeneration

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Therapeutic targeting of angiogenesis molecular pathways in angiogenesis-dependent diseases

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10.3390/MOLECULES24071219

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30925755 AND SRC:MED&resulttype=core&format=json

1 May 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30925755 AND SRC:MED&resulttype=core&format=json

1 May 2020

PubMed publication ID

30925755

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