PD-1 Primarily Targets TCR Signal in the Inhibition of Functional T Cell Activation (Q64102122)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31001256 AND SRC:MED&resulttype=core&format=json

10 April 2020

title

PD-1 Primarily Targets TCR Signal in the Inhibition of Functional T Cell Activation (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31001256 AND SRC:MED&resulttype=core&format=json

10 April 2020

0 references

0 references

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31001256 AND SRC:MED&resulttype=core&format=json

10 April 2020

Kenji Shimizu

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31001256 AND SRC:MED&resulttype=core&format=json

10 April 2020

Takumi Maruhashi

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31001256 AND SRC:MED&resulttype=core&format=json

10 April 2020

5

Mizuki Watada

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31001256 AND SRC:MED&resulttype=core&format=json

10 April 2020

7

Taku Okazaki

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31001256 AND SRC:MED&resulttype=core&format=json

10 April 2020

author name string

Reina Mizuno

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31001256 AND SRC:MED&resulttype=core&format=json

10 April 2020

Il-Mi Okazaki

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31001256 AND SRC:MED&resulttype=core&format=json

10 April 2020

language of work or name

English

0 references

publication date

29 March 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31001256 AND SRC:MED&resulttype=core&format=json

10 April 2020

published in

Frontiers in Immunology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31001256 AND SRC:MED&resulttype=core&format=json

10 April 2020

volume

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31001256 AND SRC:MED&resulttype=core&format=json

10 April 2020

page(s)

630

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31001256 AND SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

10 April 2020

copyright license

start time

29 March 2019

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

pEF-BOS, a powerful mammalian expression vector

1 reference

12 December 2020

Rapid activation of the T-cell tyrosine protein kinase pp56lck by the CD45 phosphotyrosine phosphatase

1 reference

12 December 2020

Antigen recognition by H-2-restricted T cells. I. Cell-free antigen processing

1 reference

12 December 2020

Differential T cell costimulatory requirements in CD28-deficient mice

1 reference

12 December 2020

CD28 is required for germinal center formation.

1 reference

12 December 2020

Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation

1 reference

12 December 2020

Costimulation of T cells by B7-H2, a B7-like molecule that binds ICOS

1 reference

12 December 2020

Autoimmune dilated cardiomyopathy in PD-1 receptor-deficient mice

1 reference

12 December 2020

ICOS co-stimulatory receptor is essential for T-cell activation and function

1 reference

12 December 2020

ICOS is critical for CD40-mediated antibody class switching

1 reference

12 December 2020

ICOS is essential for effective T-helper-cell responses

1 reference

12 December 2020

Enhancement of CD8 T cell responses by ICOS/B7h costimulation

1 reference

12 December 2020

PD-1 immunoreceptor inhibits B cell receptor-mediated signaling by recruiting src homology 2-domain-containing tyrosine phosphatase 2 to phosphotyrosine

1 reference

12 December 2020

PD-1:PD-L inhibitory pathway affects both CD4( ) and CD8( ) T cells and is overcome by IL-2

1 reference

12 December 2020

Differential expression of PD-L1 and PD-L2, ligands for an inhibitory receptor PD-1, in the cells of lymphohematopoietic tissues.

1 reference

12 December 2020

Program death-1 engagement upon TCR activation has distinct effects on costimulation and cytokine-driven proliferation: attenuation of ICOS, IL-4, and IL-21, but not CD28, IL-7, and IL-15 responses

1 reference

12 December 2020

Continuous T cell receptor signaling required for synapse maintenance and full effector potential

1 reference

12 December 2020

T-cell priming by dendritic cells in lymph nodes occurs in three distinct phases

1 reference

12 December 2020

PD-1 inhibits T-cell receptor induced phosphorylation of the ZAP70/CD3zeta signalosome and downstream signaling to PKCtheta

1 reference

12 December 2020

The role of ICOS in the CXCR5 follicular B helper T cell maintenance in vivo

1 reference

12 December 2020

CTLA-4 and PD-1 receptors inhibit T-cell activation by distinct mechanisms

1 reference

12 December 2020

Restoring function in exhausted CD8 T cells during chronic viral infection

1 reference

12 December 2020

Low surface expression of B7-1 (CD80) is an immunoescape mechanism of colon carcinoma

1 reference

12 December 2020

ICOS cooperates with CD28, IL-2, and IFN-gamma and modulates activation of human naïve CD4 T cells

1 reference

12 December 2020

PD-1 and PD-1 ligands: from discovery to clinical application

1 reference

12 December 2020

Fcgamma receptors as regulators of immune responses

1 reference

12 December 2020

T cell sensing of antigen dose governs interactive behavior with dendritic cells and sets a threshold for T cell activation

1 reference

12 December 2020

How T cells 'find' the right dendritic cell

1 reference

12 December 2020

T-cell activation by dendritic cells in the lymph node: lessons from the movies

1 reference

12 December 2020

PD-1 regulates germinal center B cell survival and the formation and affinity of long-lived plasma cells

1 reference

12 December 2020

CD4 T Cells Promote Rather than Control Tuberculosis in the Absence of PD-1–Mediated Inhibition

1 reference

12 December 2020

PD-1 and LAG-3 inhibitory co-receptors act synergistically to prevent autoimmunity in mice

1 reference

12 December 2020

Follicular helper CD4 T cells (TFH)

1 reference

12 December 2020

Knockout rats generated by embryo microinjection of TALENs.

1 reference

12 December 2020

The inhibitory receptor PD-1 regulates IgA selection and bacterial composition in the gut

1 reference

12 December 2020

Programmed cell death 1 forms negative costimulatory microclusters that directly inhibit T cell receptor signaling by recruiting phosphatase SHP2.

1 reference

12 December 2020

Multiplex genome engineering using CRISPR/Cas systems

1 reference

12 December 2020

RNA-guided human genome engineering via Cas9

1 reference

12 December 2020

A rheostat for immune responses: the unique properties of PD-1 and their advantages for clinical application

1 reference

12 December 2020

ICOS maintains the T follicular helper cell phenotype by down-regulating Krüppel-like factor 2.

1 reference

12 December 2020

The transcription factor KLF2 restrains CD4⁺ T follicular helper cell differentiation.

1 reference

12 December 2020

Choosing the Right Tool for the Job: RNAi, TALEN, or CRISPR.

1 reference

12 December 2020

Initiation of T cell signaling by CD45 segregation at 'close contacts'

1 reference

12 December 2020

Coinhibitory Pathways in the B7-CD28 Ligand-Receptor Family

1 reference

12 December 2020

CD28 Costimulation: From Mechanism to Therapy

1 reference

12 December 2020

T cell costimulatory receptor CD28 is a primary target for PD-1-mediated inhibition.

1 reference

12 December 2020

Rescue of exhausted CD8 T cells by PD-1-targeted therapies is CD28-dependent.

1 reference

12 December 2020

PD-L1 on tumor cells is sufficient for immune evasion in immunogenic tumors and inhibits CD8 T cell cytotoxicity.

1 reference

12 December 2020

In vitro reconstitution of T cell receptor-mediated segregation of the CD45 phosphatase.

1 reference

12 December 2020

Regulation and Function of the PD-L1 Checkpoint.

1 reference

12 December 2020

Cancer immunotherapy using checkpoint blockade.

1 reference

12 December 2020

PD-1 Controls Follicular T Helper Cell Positioning and Function

1 reference

12 December 2020

LAG-3 inhibits the activation of CD4 T cells that recognize stable pMHCII through its conformation-dependent recognition of pMHCII

1 reference

12 December 2020

Identifiers

DOI

10.3389/FIMMU.2019.00630

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31001256 AND SRC:MED&resulttype=core&format=json

10 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31001256 AND SRC:MED&resulttype=core&format=json

10 April 2020

PubMed publication ID

31001256

1 reference