Cancer Immune Checkpoint Inhibitor Therapy and the Gut Microbiota (Q64097144)

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12 April 2020

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8 February 2021

Cancer Immune Checkpoint Inhibitor Therapy and the Gut Microbiota (English)

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12 April 2020

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8 February 2021

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Amit Reddy

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Brooks D. Rabideau

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author name string

Sachin Deshmukh

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John Lightcap

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Maureen Hayes

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Steven McClellan

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Seema Singh

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Bruce Roberts

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T Grant Glover

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Andrew Y Koh

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publication date

1 January 2019

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Integrative Cancer Therapies

12 April 2020

published in

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8 February 2021

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page(s)

1534735419846379

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Creative Commons Attribution-NonCommercial

12 April 2020

copyright license

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8 February 2021

Enhancement of antitumor immunity by CTLA-4 blockade

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12 December 2020

Allogeneic compared with autologous stem cell transplantation in the treatment of patients younger than 46 years with acute myeloid leukemia (AML) in first complete remission (CR1): an intention-to-treat analysis of the EORTC/GIMEMAAML-10 trial

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12 December 2020

Single-agent interleukin-2 in the treatment of metastatic melanoma

1 reference

12 December 2020

Basic and therapeutic trial results obtained in the spontaneous AK leukemia (lymphoma) model-end of 1971.

1 reference

12 December 2020

Ipilimumab plus dacarbazine for previously untreated metastatic melanoma

1 reference

12 December 2020

Commensal bacteria control cancer response to therapy by modulating the tumor microenvironment.

1 reference

12 December 2020

The intestinal microbiota modulates the anticancer immune effects of cyclophosphamide

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12 December 2020

Diet rapidly and reproducibly alters the human gut microbiome

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12 December 2020

Genetic basis for clinical response to CTLA-4 blockade in melanoma

1 reference

12 December 2020

Commensal Bifidobacterium promotes antitumor immunity and facilitates anti-PD-L1 efficacy

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12 December 2020

Anticancer immunotherapy by CTLA-4 blockade relies on the gut microbiota

1 reference

12 December 2020

Meta-analysis of regression of advanced solid tumors in patients receiving placebo or no anti-cancer therapy in prospective trials

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12 December 2020

Intestinal microbiome analyses identify melanoma patients at risk for checkpoint-blockade-induced colitis

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12 December 2020

PD-L1 expression in cancer patients receiving anti PD-1/PD-L1 antibodies: A systematic review and meta-analysis.

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12 December 2020

Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade

1 reference

12 December 2020

Ruthenibacterium lactatiformans gen. nov., sp. nov., an anaerobic, lactate-producing member of the family Ruminococcaceae isolated from human faeces.

1 reference

12 December 2020

Effect of room temperature transport vials on DNA quality and phylogenetic composition of faecal microbiota of elderly adults and infants.

1 reference

12 December 2020

Enterococcus hirae and Barnesiella intestinihominis Facilitate Cyclophosphamide-Induced Therapeutic Immunomodulatory Effects

1 reference

12 December 2020

High cytotoxic T-lymphocyte-associated antigen 4 and phospho-Akt expression in tumor samples predicts poor clinical outcomes in ipilimumab-treated melanoma patients.

1 reference

12 December 2020

Somatic Mutations and Neoepitope Homology in Melanomas Treated with CTLA-4 Blockade

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12 December 2020

cGAS is essential for the antitumor effect of immune checkpoint blockade

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12 December 2020

Baseline gut microbiota predicts clinical response and colitis in metastatic melanoma patients treated with ipilimumab

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12 December 2020

Homeostatic Immunity and the Microbiota

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12 December 2020

Potential for Monitoring Gut Microbiota for Diagnosing Infections and Graft-versus-Host Disease in Cancer and Stem Cell Transplant Patients.

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12 December 2020

Identification of essential genes for cancer immunotherapy.

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12 December 2020

Oral spore-based probiotic supplementation was associated with reduced incidence of post-prandial dietary endotoxin, triglycerides, and disease risk biomarkers

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12 December 2020

The Microbial Metabolite Butyrate Induces Expression of Th1-Associated Factors in CD4 T Cells

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12 December 2020

Metagenomic Shotgun Sequencing and Unbiased Metabolomic Profiling Identify Specific Human Gut Microbiota and Metabolites Associated with Immune Checkpoint Therapy Efficacy in Melanoma Patients

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12 December 2020

Gut microbiome modulates response to anti-PD-1 immunotherapy in melanoma patients.

1 reference

12 December 2020

Gut microbiome influences efficacy of PD-1-based immunotherapy against epithelial tumors

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12 December 2020

Live Faecalibacterium prausnitzii induces greater TLR2 and TLR2/6 activation than the dead bacterium in an apical anaerobic co-culture system

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12 December 2020

A neoantigen fitness model predicts tumour response to checkpoint blockade immunotherapy.

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12 December 2020

Identification of unique neoantigen qualities in long-term survivors of pancreatic cancer.

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12 December 2020

The commensal microbiome is associated with anti-PD-1 efficacy in metastatic melanoma patients.

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12 December 2020

The cytosolic sensor STING is required for intestinal homeostasis and control of inflammation.

1 reference

12 December 2020

Association of body-mass index and outcomes in patients with metastatic melanoma treated with targeted therapy, immunotherapy, or chemotherapy: a retrospective, multicohort analysis.

1 reference

12 December 2020

Methodology challenges in studying human gut microbiota - effects of collection, storage, DNA extraction and next generation sequencing technologies.

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12 December 2020

Anti-CTLA-4 therapy requires an Fc domain for efficacy.

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12 December 2020

In vitro co-cultures of human gut bacterial species as predicted from co-occurrence network analysis.

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12 December 2020

Negative association of antibiotics on clinical activity of immune checkpoint inhibitors in patients with advanced renal cell and non-small cell lung cancer.

1 reference

12 December 2020

Talimogene Laherparepvec combined with anti-PD-1 based immunotherapy for unresectable stage III-IV melanoma: a case series.

1 reference

12 December 2020

Best practices for analysing microbiomes

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12 December 2020

Personalized Gut Mucosal Colonization Resistance to Empiric Probiotics Is Associated with Unique Host and Microbiome Features

1 reference

12 December 2020

Microbiome 101: Studying, Analyzing, and Interpreting Gut Microbiome Data for Clinicians

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12 December 2020

Regulation of the effector function of CD8 T cells by gut microbiota-derived metabolite butyrate

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12 December 2020

Body mass index may predict the response to ipilimumab in metastatic melanoma: An observational multi-centre study

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12 December 2020

Recovery of gut microbiota of healthy adults following antibiotic exposure

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12 December 2020

Use of broad-spectrum antibiotics impacts outcome in patients treated with immune checkpoint inhibitors

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12 December 2020

Current Evidence in Delivery and Therapeutic Uses of Fecal Microbiota Transplantation in Human Diseases-Clostridium difficile Disease and Beyond

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12 December 2020

Long-term impact of oral vancomycin, ciprofloxacin and metronidazole on the gut microbiota in healthy humans

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12 December 2020

Gold Standard Assessment of Immunogenic Cell Death in Oncological Mouse Models

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12 December 2020

Posttransplant Malignancy

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12 December 2020

Successful Anti-PD-1 Cancer Immunotherapy Requires T Cell-Dendritic Cell Crosstalk Involving the Cytokines IFN-γ and IL-12

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12 December 2020

WNT/β-catenin Pathway Activation Correlates with Immune Exclusion across Human Cancers

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12 December 2020

Tumor mutational load predicts survival after immunotherapy across multiple cancer types

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12 December 2020

Use of archival versus newly collected tumor samples for assessing PD-L1 expression and overall survival: an updated analysis of KEYNOTE-010 trial

1 reference

12 December 2020

Extensive Unexplored Human Microbiome Diversity Revealed by Over 150,000 Genomes from Metagenomes Spanning Age, Geography, and Lifestyle

1 reference

12 December 2020

A defined commensal consortium elicits CD8 T cells and anti-cancer immunity

1 reference

12 December 2020

Association between antibiotics use and outcome in patients with NSCLC treated with immunotherapeutics

1 reference

12 December 2020

Identifiers

DOI

10.1177/1534735419846379

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31014119 AND SRC:MED&resulttype=core&format=json

12 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31014119 AND SRC:MED&resulttype=core&format=json

12 April 2020

PubMed publication ID

31014119

1 reference