Is autophagy an elective strategy to protect neurons from dysregulated cholesterol metabolism? (Q64096430)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30632494 AND SRC:MED&resulttype=core&format=json

18 April 2020

title

Is autophagy an elective strategy to protect neurons from dysregulated cholesterol metabolism? (English)

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18 April 2020

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3

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18 April 2020

Annalisa Marcuzzi

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4

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18 April 2020

author name string

Elisa Piscianz

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1

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18 April 2020

Liza Vecchi Brumatti

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2

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18 April 2020

language of work or name

English

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publication date

1 April 2019

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Neural Regeneration Research

18 April 2020

published in

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18 April 2020

volume

14

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18 April 2020

issue

4

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18 April 2020

page(s)

582-587

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Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

18 April 2020

cites work

1 reference

12 December 2020

Linkage of Niemann-Pick disease type C to human chromosome 18

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12 December 2020

Niemann-Pick C1 disease gene: homology to mediators of cholesterol homeostasis

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Apoptotic Membrane Blebbing Is Regulated by Myosin Light Chain Phosphorylation

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12 December 2020

Lipid changes in Niemann-Pick disease type C brain: personal experience and review of the literature

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12 December 2020

The Smith-Lemli-Opitz syndrome

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12 December 2020

Apoptosis in development

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Identification of HE1 as the second gene of Niemann-Pick C disease

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A NEWLY RECOGNIZED SYNDROME OF MULTIPLE CONGENITAL ANOMALIES.

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Cargo proteins facilitate the formation of transport vesicles in the cytoplasm to vacuole targeting pathway

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Molecular mechanisms of caspase regulation during apoptosis

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Actin-myosin-based contraction is responsible for apoptotic nuclear disintegration

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Self-eating and self-killing: crosstalk between autophagy and apoptosis

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12 December 2020

Autophagy revisited: a conversation with Christian de Duve

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12 December 2020

Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum

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12 December 2020

A subdomain of the endoplasmic reticulum forms a cradle for autophagosome formation

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12 December 2020

Niemann-Pick disease type C

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12 December 2020

Biological activities of 7-dehydrocholesterol-derived oxysterols: implications for Smith-Lemli-Opitz syndrome

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12 December 2020

Autophagosome formation and molecular mechanism of autophagy.

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12 December 2020

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

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12 December 2020

Cholesterol metabolism in neurons and astrocytes.

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12 December 2020

Recommendations for the diagnosis and management of Niemann–Pick disease type C: An update

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Smith-Lemli-Opitz syndrome: phenotype, natural history, and epidemiology

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Mevalonate kinase deficiency, a metabolic autoinflammatory disease.

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The cell biology of disease: lysosomal storage disorders: the cellular impact of lysosomal dysfunction

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Caspase-8 cleaves its substrates from the plasma membrane upon CD95-induced apoptosis

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Myosin phosphatase is inactivated by caspase-3 cleavage and phosphorylation of myosin phosphatase targeting subunit 1 during apoptosis

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12 December 2020

Cholesterol metabolism deficiency

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12 December 2020

Quality control gone wrong: mitochondria, lysosomal storage disorders and neurodegeneration

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12 December 2020

Location and membrane sources for autophagosome formation - from ER-mitochondria contact sites to Golgi-endosome-derived carriers

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12 December 2020

Impaired autophagy in the lipid-storage disorder Niemann-Pick type C1 disease

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12 December 2020

Activity of protein kinase RIPK3 determines whether cells die by necroptosis or apoptosis

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12 December 2020

Unprenylated RhoA contributes to IL-1β hypersecretion in mevalonate kinase deficiency model through stimulation of Rac1 activity.

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12 December 2020

PI3P phosphatase activity is required for autophagosome maturation and autolysosome formation.

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12 December 2020

Inflammatory outcomes of apoptosis, necrosis and necroptosis

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12 December 2020

Cholesterol metabolism and immunity.

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12 December 2020

Elevated Autophagy and Mitochondrial Dysfunction in the Smith-Lemli-Opitz Syndrome.

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12 December 2020

Structure of the human autophagy initiating kinase ULK1 in complex with potent inhibitors.

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12 December 2020

Cholesterol metabolism and homeostasis in the brain

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12 December 2020

Innovative Target Therapies Are Able to Block the Inflammation Associated with Dysfunction of the Cholesterol Biosynthesis Pathway

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12 December 2020

Basic and Clinical Observations of Mevalonate Depletion on the Mevalonate Signaling Pathway

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12 December 2020

Autophagy, lipophagy and lysosomal lipid storage disorders

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12 December 2020

Brain metabolism as a modulator of autophagy in neurodegeneration

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12 December 2020

The ULK1 complex mediates MTORC1 signaling to the autophagy initiation machinery via binding and phosphorylating ATG14.

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12 December 2020

Necroptosis-independent signaling by the RIP kinases in inflammation

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12 December 2020

Efficacy and ototoxicity of different cyclodextrins in Niemann-Pick C disease

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12 December 2020

The mevalonate pathway as a metabolic requirement for autophagy-implications for growth control, proteostasis, and disease

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12 December 2020

Niemann-Pick type C2 deficiency impairs autophagy-lysosomal activity, mitochondrial function, and TLR signaling in adipocytes

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12 December 2020

Neuroprotection Through Rapamycin-Induced Activation of Autophagy and PI3K/Akt1/mTOR/CREB Signaling Against Amyloid-β-Induced Oxidative Stress, Synaptic/Neurotransmission Dysfunction, and Neurodegeneration in Adult Rats

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12 December 2020

Necroptosis-like Neuronal Cell Death Caused by Cellular Cholesterol Accumulation

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12 December 2020

The mevalonate pathway in neurons: It's not just about cholesterol

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12 December 2020

Linking mitochondrial dysfunction to neurodegeneration in lysosomal storage diseases.

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12 December 2020

Necroptosis in neurodegenerative diseases: a potential therapeutic target

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12 December 2020

Autophagy, its mechanisms and regulation: Implications in neurodegenerative diseases

1 reference

12 December 2020

Intracellular Cholesterol Trafficking and Impact in Neurodegeneration

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12 December 2020

Lysosomal and Mitochondrial Liaisons in Niemann-Pick Disease

1 reference

12 December 2020

The intersection of lysosomal and endoplasmic reticulum calcium with autophagy defects in lysosomal diseases.

1 reference

12 December 2020

Neuronal Dysfunction Associated with Cholesterol Deregulation.

1 reference

12 December 2020

Niemann-Pick Type C2 Protein Regulates Free Cholesterol Accumulation and Influences Hepatic Stellate Cell Proliferation and Mitochondrial Respiration Function.

1 reference

12 December 2020

Compromised phagosome maturation underlies RPE pathology in cell culture and whole animal models of Smith-Lemli-Opitz Syndrome

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12 December 2020

A new hypothesis for Parkinson's disease pathogenesis: GTPase-p38 MAPK signaling and autophagy as convergence points of etiology and genomics

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12 December 2020

Coordinate regulation of mutant NPC1 degradation by selective ER autophagy and MARCH6-dependent ERAD

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12 December 2020

Intracellular cholesterol accumulation and coenzyme Q deficiency in Familial Hypercholesterolemia

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12 December 2020

Trehalose induces autophagy via lysosomal-mediated TFEB activation in models of motoneuron degeneration

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12 December 2020

Identifiers

DOI

10.4103/1673-5374.247441

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30632494 AND SRC:MED&resulttype=core&format=json

18 April 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30632494 AND SRC:MED&resulttype=core&format=json

18 April 2020

PubMed publication ID

30632494

1 reference