Plans for HDBase—a research community website for Huntington's Disease (Q63951832)

1

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Kim McCormick

2

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Dan Goldowitz

3

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Emma Hockly

4

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Carl Johnson

5

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Bruce Kristal

6

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Ray Truant

8

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Minka van Beuzekom

Clinical neuroscience research

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publication date

September 2003

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published in

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volume

3

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issue

3

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page(s)

197-217

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7 January 2021

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7 January 2021

Collecting and harvesting biological data: the GPCRDB and NucleaRDB information systems

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7 January 2021

A patient-supported strategy for therapy development in amyotrophic lateral sclerosis (ALS)

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7 January 2021

NCBI Reference Sequence project: update and current status

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7 January 2021

Gene ontology: tool for the unification of biology

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7 January 2021

BIND--The Biomolecular Interaction Network Database

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What's new in the library? What's new in GenBank? let PubCrawler tell you.

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7 January 2021

The generic genome browser: a building block for a model organism system database

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7 January 2021

The UCSC Genome Browser Database

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7 January 2021

INFORMATION ACCESS: Building A "GenBank" of the Published Literature

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7 January 2021

Therapeutic effects of coenzyme Q10 and remacemide in transgenic mouse models of Huntington's disease.

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https://api.crossref.org/works/10.1016/S1566-2772(03)50062-8

7 January 2021

Coenzyme Q10 as a possible treatment for neurodegenerative diseases

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https://api.crossref.org/works/10.1016/S1566-2772(03)50062-8

7 January 2021

Coenzyme Q10 administration and its potential for treatment of neurodegenerative diseases

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https://api.crossref.org/works/10.1016/S1566-2772(03)50062-8

7 January 2021

Coenzyme Q10 and remacemide hydrochloride ameliorate motor deficits in a Huntington's disease transgenic mouse model

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https://api.crossref.org/works/10.1016/S1566-2772(03)50062-8

7 January 2021

Neuroprotective effects of creatine in a transgenic mouse model of Huntington's disease.

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https://api.crossref.org/works/10.1016/S1566-2772(03)50062-8

7 January 2021

Creatine increase survival and delays motor symptoms in a transgenic animal model of Huntington's disease

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https://api.crossref.org/works/10.1016/S1566-2772(03)50062-8

7 January 2021

Tauroursodeoxycholic acid, a bile acid, is neuroprotective in a transgenic animal model of Huntington's disease.

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https://api.crossref.org/works/10.1016/S1566-2772(03)50062-8

7 January 2021

Lipoic acid improves survival in transgenic mouse models of Huntington's disease

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https://api.crossref.org/works/10.1016/S1566-2772(03)50062-8

7 January 2021

Therapeutic effects of cystamine in a murine model of Huntington's disease.

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https://api.crossref.org/works/10.1016/S1566-2772(03)50062-8

7 January 2021

Prolonged survival and decreased abnormal movements in transgenic model of Huntington disease, with administration of the transglutaminase inhibitor cystamine

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https://api.crossref.org/works/10.1016/S1566-2772(03)50062-8

7 January 2021

Essential fatty acids given from conception prevent topographies of motor deficit in a transgenic model of Huntington's disease

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https://api.crossref.org/works/10.1016/S1566-2772(03)50062-8

7 January 2021

Riluzole prolongs survival time and alters nuclear inclusion formation in a transgenic mouse model of Huntington's disease

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https://api.crossref.org/works/10.1016/S1566-2772(03)50062-8

7 January 2021

Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, ameliorates motor deficits in a mouse model of Huntington's disease

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https://api.crossref.org/works/10.1016/S1566-2772(03)50062-8

7 January 2021

Minocycline inhibits caspase-1 and caspase-3 expression and delays mortality in a transgenic mouse model of Huntington disease

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https://api.crossref.org/works/10.1016/S1566-2772(03)50062-8

7 January 2021

Minocycline slows progress of Huntington's disease in mice

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https://api.crossref.org/works/10.1016/S1566-2772(03)50062-8

7 January 2021

Dichloroacetate exerts therapeutic effects in transgenic mouse models of Huntington's disease

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7 January 2021

Inhibition of caspase-1 slows disease progression in a mouse model of Huntington's disease

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7 January 2021

Pivotal role of oligomerization in expanded polyglutamine neurodegenerative disorders.

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7 January 2021

Environmental enrichment slows disease progression in R6/2 Huntington's disease mice

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7 January 2021

Environmental stimulation increases survival in mice transgenic for exon 1 of the Huntington's disease gene

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https://api.crossref.org/works/10.1016/S1566-2772(03)50062-8

7 January 2021

Delaying the onset of Huntington's in mice

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https://api.crossref.org/works/10.1016/S1566-2772(03)50062-8

7 January 2021

Dietary restriction normalizes glucose metabolism and BDNF levels, slows disease progression, and increases survival in huntingtin mutant mice

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https://api.crossref.org/works/10.1016/S1566-2772(03)50062-8

7 January 2021

Anterior cingulate cortical transplantation in transgenic Huntington's disease mice

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7 January 2021

Striatal transplantation in a transgenic mouse model of Huntington's disease

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7 January 2021

Decreased expression of striatal signaling genes in a mouse model of Huntington's disease

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7 January 2021

Polyglutamine expansions cause decreased CRE-mediated transcription and early gene expression changes prior to cell death in an inducible cell model of Huntington's disease

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https://api.crossref.org/works/10.1016/S1566-2772(03)50062-8

7 January 2021

Increased huntingtin protein length reduces the number of polyglutamine-induced gene expression changes in mouse models of Huntington's disease

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https://api.crossref.org/works/10.1016/S1566-2772(03)50062-8

7 January 2021

Identification of a presymptomatic molecular phenotype in Hdh CAG knock-in mice

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https://api.crossref.org/works/10.1016/S1566-2772(03)50062-8

7 January 2021

Altered transcriptional regulation in cells expressing the expanded polyglutamine androgen receptor

1 reference

https://api.crossref.org/works/10.1016/S1566-2772(03)50062-8

7 January 2021

Dysregulation of gene expression in the R6/2 model of polyglutamine disease: parallel changes in muscle and brain

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https://api.crossref.org/works/10.1016/S1566-2772(03)50062-8

7 January 2021

Polyglutamine and transcription: gene expression changes shared by DRPLA and Huntington's disease mouse models reveal context-independent effects

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https://api.crossref.org/works/10.1016/S1566-2772(03)50062-8

7 January 2021

Early transcriptional profiles in huntingtin-inducible striatal cells by microarray analyses

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https://api.crossref.org/works/10.1016/S1566-2772(03)50062-8

7 January 2021

Protein tyrosine phosphatases are up-regulated and participate in cell death induced by polyglutamine expansion

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https://api.crossref.org/works/10.1016/S1566-2772(03)50062-8

7 January 2021

Gene Expression Omnibus: NCBI gene expression and hybridization array data repository

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7 January 2021

ArrayExpress--a public repository for microarray gene expression data at the EBI

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https://api.crossref.org/works/10.1016/S1566-2772(03)50062-8

7 January 2021

Loss of normal huntingtin function: new developments in Huntington's disease research

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7 January 2021

MINT: a Molecular INTeraction database

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7 January 2021

Initial sequencing and comparative analysis of the mouse genome

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7 January 2021

Improved tools for biological sequence comparison

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7 January 2021

Rapid and sensitive sequence comparison with FASTP and FASTA

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https://api.crossref.org/works/10.1016/S1566-2772(03)50062-8

7 January 2021

Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice

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7 January 2021

Length-dependent gametic CAG repeat instability in the Huntington's disease knock-in mouse

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https://api.crossref.org/works/10.1016/S1566-2772(03)50062-8

7 January 2021

Changes in cortical and striatal neurons predict behavioral and electrophysiological abnormalities in a transgenic murine model of Huntington's disease

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https://api.crossref.org/works/10.1016/S1566-2772(03)50062-8

7 January 2021

A YAC mouse model for Huntington's disease with full-length mutant huntingtin, cytoplasmic toxicity, and selective striatal neurodegeneration.

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7 January 2021

A Cell Culture Model for Androgen Effects in Motor Neurons

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7 January 2021

Intranuclear inclusions and neuritic aggregates in transgenic mice expressing a mutant N-terminal fragment of huntingtin

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https://api.crossref.org/works/10.1016/S1566-2772(03)50062-8

7 January 2021

Nuclear accumulation of truncated atrophin-1 fragments in a transgenic mouse model of DRPLA.

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https://api.crossref.org/works/10.1016/S1566-2772(03)50062-8

7 January 2021

Expansion of polyglutamine repeat in huntingtin leads to abnormal protein interactions involving calmodulin

1 reference

https://api.crossref.org/works/10.1016/S1566-2772(03)50062-8

7 January 2021

Huntingtin interacts with cystathionine beta-synthase

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https://api.crossref.org/works/10.1016/S1566-2772(03)50062-8

7 January 2021

The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription

1 reference

https://api.crossref.org/works/10.1016/S1566-2772(03)50062-8

7 January 2021

SH3 domain-dependent association of huntingtin with epidermal growth factor receptor signaling complexes

1 reference

https://api.crossref.org/works/10.1016/S1566-2772(03)50062-8

7 January 2021

Isolation of a 40-kDa Huntingtin-associated protein

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https://api.crossref.org/works/10.1016/S1566-2772(03)50062-8

7 January 2021

Huntingtin interacts with a family of WW domain proteins

1 reference

https://api.crossref.org/works/10.1016/S1566-2772(03)50062-8

7 January 2021

Huntingtin and DRPLA proteins selectively interact with the enzyme GAPDH.

1 reference

https://api.crossref.org/works/10.1016/S1566-2772(03)50062-8

7 January 2021

A huntingtin-associated protein enriched in brain with implications for pathology

1 reference

https://api.crossref.org/works/10.1016/S1566-2772(03)50062-8

7 January 2021

HIP-I: a huntingtin interacting protein isolated by the yeast two-hybrid system

1 reference

https://api.crossref.org/works/10.1016/S1566-2772(03)50062-8

7 January 2021

HIP1, a human homologue of S. cerevisiae Sla2p, interacts with membrane-associated huntingtin in the brain

1 reference

https://api.crossref.org/works/10.1016/S1566-2772(03)50062-8

7 January 2021

Huntingtin is ubiquitinated and interacts with a specific ubiquitin-conjugating enzyme

1 reference

https://api.crossref.org/works/10.1016/S1566-2772(03)50062-8

7 January 2021

Recruitment and activation of caspase-8 by the Huntingtin-interacting protein Hip-1 and a novel partner Hippi

1 reference

https://api.crossref.org/works/10.1016/S1566-2772(03)50062-8

7 January 2021

Activation of MLK2-mediated signaling cascades by polyglutamine-expanded huntingtin

1 reference

https://api.crossref.org/works/10.1016/S1566-2772(03)50062-8

7 January 2021

Aberrant interactions of transcriptional repressor proteins with the Huntington's disease gene product, huntingtin

1 reference

https://api.crossref.org/works/10.1016/S1566-2772(03)50062-8

7 January 2021

SH3GL3 associates with the Huntingtin exon 1 protein and promotes the formation of polygln-containing protein aggregates

1 reference

https://api.crossref.org/works/10.1016/S1566-2772(03)50062-8

7 January 2021

Sp1 and TAFII130 transcriptional activity disrupted in early Huntington's disease

1 reference

https://api.crossref.org/works/10.1016/S1566-2772(03)50062-8

7 January 2021

The Gln-Ala repeat transcriptional activator CA150 interacts with huntingtin: neuropathologic and genetic evidence for a role in Huntington's disease pathogenesis

1 reference

https://api.crossref.org/works/10.1016/S1566-2772(03)50062-8

7 January 2021

Cdc42-interacting protein 4 binds to huntingtin: neuropathologic and biological evidence for a role in Huntington's disease

1 reference

https://api.crossref.org/works/10.1016/S1566-2772(03)50062-8

7 January 2021