Defects in efferent duct multiciliogenesis underlie male infertility in GEMC1-, MCIDAS- or CCNO-deficient mice (Q63383929)

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1 May 2020

title

Defects in efferent duct multiciliogenesis underlie male infertility in GEMC1-, MCIDAS- or CCNO-deficient mice (English)

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1 May 2020

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1

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Gabriel Gil-Gómez

3

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1 May 2020

Mònica Aguilera

6

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Haotian Zhao

9

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Travis H Stracker

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author name string

Michael Lewis

2

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Zhiyuan Han

4

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Hao Lu

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Neus Prats

7

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Sudipto Roy

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publication date

23 April 2019

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volume

146

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issue

8

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Changes in distribution and staining reactivity of PAS-positive material in the mouse epididymal duct after efferent duct ligation

1 May 2020

page(s)

dev162628

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cites work

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12 December 2020

Distribution of vimentin-type intermediate filaments in Sertoli cells of the human testis, normal and pathologic

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12 December 2020

Mutation of the mouse hepatocyte nuclear factor/forkhead homologue 4 gene results in an absence of cilia and random left-right asymmetry

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12 December 2020

Fluid and electrolyte reabsorption in the ductuli efferentes testis

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12 December 2020

Role of f-box factor foxj1 in differentiation of ciliated airway epithelial cells

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12 December 2020

E2f4 is required for normal development of the airway epithelium

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12 December 2020

TAp73 knockout shows genomic instability with infertility and tumor suppressor functions

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12 December 2020

Identification of a novel cyclin required for the intrinsic apoptosis pathway in lymphoid cells.

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12 December 2020

Foxj1 transcription factors are master regulators of the motile ciliogenic program

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12 December 2020

Notch signaling controls the balance of ciliated and secretory cell fates in developing airways

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12 December 2020

RFX3 governs growth and beating efficiency of motile cilia in mouse and controls the expression of genes involved in human ciliopathies

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12 December 2020

GEMC1 is a TopBP1-interacting protein required for chromosomal DNA replication

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12 December 2020

Estrogen, efferent ductules, and the epididymis.

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12 December 2020

Control of vertebrate multiciliogenesis by miR-449 through direct repression of the Delta/Notch pathway

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12 December 2020

RFX2 is broadly required for ciliogenesis during vertebrate development.

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12 December 2020

Multicilin promotes centriole assembly and ciliogenesis during multiciliate cell differentiation

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12 December 2020

RFX3 modulation of FOXJ1 regulation of cilia genes in the human airway epithelium.

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12 December 2020

Myb promotes centriole amplification and later steps of the multiciliogenesis program.

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12 December 2020

TAp73 is required for spermatogenesis and the maintenance of male fertility

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12 December 2020

TAp73 is essential for germ cell adhesion and maturation in testis.

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12 December 2020

Mutations in CCNO result in congenital mucociliary clearance disorder with reduced generation of multiple motile cilia

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12 December 2020

miR-34/449 miRNAs are required for motile ciliogenesis by repressing cp110.

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12 December 2020

Multicilin drives centriole biogenesis via E2f proteins

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12 December 2020

Two miRNA clusters, miR-34b/c and miR-449, are essential for normal brain development, motile ciliogenesis, and spermatogenesis

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12 December 2020

MCIDAS mutations result in a mucociliary clearance disorder with reduced generation of multiple motile cilia

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12 December 2020

Myb permits multilineage airway epithelial cell differentiation

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12 December 2020

Oligoasthenoteratozoospermia and infertility in mice deficient for miR-34b/c and miR-449 loci

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12 December 2020

mir-34b/c and mir-449a/b/c are required for spermatogenesis, but not for the first cleavage division in mice

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12 December 2020

Cyclin O (Ccno) functions during deuterosome-mediated centriole amplification of multiciliated cells

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12 December 2020

CEP63 deficiency promotes p53-dependent microcephaly and reveals a role for the centrosome in meiotic recombination

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12 December 2020

Mcidas and GemC1 are key regulators for the generation of multiciliated ependymal cells in the adult neurogenic niche

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12 December 2020

Therapeutic antibodies reveal Notch control of transdifferentiation in the adult lung

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12 December 2020

Systematic Analysis of CCNO Variants in a Defined Population: Implications for Clinical Phenotype and Differential Diagnosis

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12 December 2020

Gmnc Is a Master Regulator of the Multiciliated Cell Differentiation Program

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12 December 2020

E2f4 and E2f5 are essential for the development of the male reproductive system

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12 December 2020

GemC1 controls multiciliogenesis in the airway epithelium

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12 December 2020

GEMC1 is a critical regulator of multiciliated cell differentiation

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12 December 2020

p73 Is Required for Multiciliogenesis and Regulates the Foxj1-Associated Gene Network.

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12 December 2020

TAp73 is a central transcriptional regulator of airway multiciliogenesis.

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12 December 2020

Calibrated mitotic oscillator drives motile ciliogenesis

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12 December 2020

Constitutive Cyclin O deficiency results in penetrant hydrocephalus, impaired growth and infertility

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12 December 2020

Cyclin-dependent kinase control of motile ciliogenesis

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12 December 2020

Distinct requirements of E2f4 versus E2f5 activity for multiciliated cell development in the zebrafish embryo

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12 December 2020

Motile cilia of the male reproductive system require miR-34/miR-449 for development and function to generate luminal turbulence

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12 December 2020

Mcidas mutant mice reveal a two-step process for the specification and differentiation of multiciliated cells in mammals

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12 December 2020

Identifiers

DOI

10.1242/DEV.162628

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30936178 AND SRC:MED&resulttype=core&format=json

1 May 2020

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1 May 2020

PubMed publication ID

30936178

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