Anti-type 2 transglutaminase antibodies as modulators of type 2 transglutaminase functions: a possible pathological role in celiac disease (Q63225367)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30136165 AND SRC:MED&resulttype=core&format=json

19 April 2020

title

Anti-type 2 transglutaminase antibodies as modulators of type 2 transglutaminase functions: a possible pathological role in celiac disease (English)

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19 April 2020

2

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19 April 2020

Ivana Caputo

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5

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19 April 2020

3

Carla Esposito

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19 April 2020

4

Marilena Lepretti

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19 April 2020

Stefania Martucciello

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1

object named as

Stefania Martucciello

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19 April 2020

publication date

22 August 2018

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Cellular and Molecular Life Sciences

19 April 2020

published in

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19 April 2020

volume

75

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19 April 2020

issue

22

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19 April 2020

page(s)

4107-4124

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Comparison of IgA-class reticulin and endomysium antibodies in coeliac disease and dermatitis herpetiformis

19 April 2020

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The p53 oncoprotein is a substrate for tissue transglutaminase kinase activity

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Phosphorylation of histones by tissue transglutaminase.

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Autoantibody targeting of brain and intestinal transglutaminase in gluten ataxia

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Antibodies against transglutaminases, peptidylarginine deiminase and citrulline in rheumatoid arthritis--new pathways to epitope spreading.

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Coeliac autoantibodies can enhance transamidating and inhibit GTPase activity of tissue transglutaminase: dependence on reaction environment and enzyme fitness

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Coeliac disease autoantibodies mediate significant inhibition of tissue transglutaminase.

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Celiac anti-tissue transglutaminase antibodies interfere with the uptake of alpha gliadin peptide 31–43 but not of peptide 57–68 by epithelial cells

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Epithelial transport and deamidation of gliadin peptides: a role for coeliac disease patient immunoglobulin A.

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Tissue transglutaminase promotes PDGF/PDGFR-mediated signaling and responses in vascular smooth muscle cells

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Autoantibodies from patients with celiac disease inhibit transglutaminase 2 binding to heparin/heparan sulfate and interfere with intestinal epithelial cell adhesion

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Extracellular TG2: emerging functions and regulation

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Celiac disease and transglutaminase 2: a model for posttranslational modification of antigens and HLA association in the pathogenesis of autoimmune disorders

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Anti-tissue transglutaminase antibodies activate intracellular tissue transglutaminase by modulating cytosolic Ca2 homeostasis

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New insights into the functions and localization of nuclear transglutaminase 2.

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Tissue transglutaminase, inflammation, and cancer: how intimate is the relationship?

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12 December 2020

A single conformational transglutaminase 2 epitope contributed by three domains is critical for celiac antibody binding and effects

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12 December 2020

RhoB is associated with the anti-angiogenic effects of celiac patient transglutaminase 2-targeted autoantibodies

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Accuracy of diagnostic antibody tests for coeliac disease in children: summary of an evidence report

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Nomenclature and listing of celiac disease relevant gluten T-cell epitopes restricted by HLA-DQ molecules.

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Cellular Functions of Tissue Transglutaminase

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High abundance of plasma cells secreting transglutaminase 2-specific IgA autoantibodies with limited somatic hypermutation in celiac disease intestinal lesions.

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Celiac disease in type 1 diabetes mellitus

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12 December 2020

Gliadin peptides induce tissue transglutaminase activation and ER-stress through Ca2 mobilization in Caco-2 cells

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12 December 2020

Degree of damage to the small bowel and serum antibody titers correlate with clinical presentation of patients with celiac disease.

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12 December 2020

Genetic disruption of the copulatory plug in mice leads to severely reduced fertility

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12 December 2020

A subset of anti-rotavirus antibodies directed against the viral protein VP7 predicts the onset of celiac disease and induces typical features of the disease in the intestinal epithelial cell line T84.

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12 December 2020

Transglutaminase 6 antibodies in the diagnosis of gluten ataxia

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12 December 2020

Transglutaminase 2-specific autoantibodies in celiac disease target clustered, N-terminal epitopes not displayed on the surface of cells

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Improving coeliac disease risk prediction by testing non-HLA variants additional to HLA variants

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Celiac disease patient IgA antibodies induce endothelial adhesion and cell polarization defects via extracellular transglutaminase 2.

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A celiac cellular phenotype, with altered LPP sub-cellular distribution, is inducible in controls by the toxic gliadin peptide P31-43

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Small bowel transglutaminase 2-specific IgA deposits in dermatitis herpetiformis

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Celiac anti-type 2 transglutaminase antibodies induce phosphoproteome modification in intestinal epithelial Caco-2 cells

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Transglutaminase regulation of cell function.

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Structural basis for the recognition in an idiotype-anti-idiotype antibody complex related to celiac disease.

1 reference

12 December 2020

Injection of celiac disease patient sera or immunoglobulins to mice reproduces a condition mimicking early developing celiac disease

1 reference

12 December 2020

Activity-regulating structural changes and autoantibody epitopes in transglutaminase 2 assessed by hydrogen/deuterium exchange.

1 reference

12 December 2020

Serological markers of enterocyte damage and apoptosis in patients with celiac disease, autoimmune diabetes mellitus and diabetes mellitus type 2.

1 reference

12 December 2020

Physiological, pathological, and structural implications of non-enzymatic protein-protein interactions of the multifunctional human transglutaminase 2

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Distinct and Synergistic Contributions of Epithelial Stress and Adaptive Immunity to Functions of Intraepithelial Killer Cells and Active Celiac Disease

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Dermatitis herpetiformis: pathognomonic transglutaminase IgA deposits in the skin and excellent prognosis on a gluten-free diet

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12 December 2020

Structural Basis for Antigen Recognition by Transglutaminase 2-specific Autoantibodies in Celiac Disease

1 reference

12 December 2020

Enhanced B-Cell Receptor Recognition of the Autoantigen Transglutaminase 2 by Efficient Catalytic Self-Multimerization

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Isopeptidase activity of human transglutaminase 2: disconnection from transamidation and characterization by kinetic parameters

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12 December 2020

Extraintestinal manifestations of coeliac disease

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12 December 2020

T cell epitopes and post-translationally modified epitopes in type 1 diabetes

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12 December 2020

Igs as Substrates for Transglutaminase 2: Implications for Autoantibody Production in Celiac Disease.

1 reference

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Celiac disease: Autoimmunity in response to food antigen

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12 December 2020

Essential Role of Transglutaminase 2 in Vascular Endothelial Growth Factor-Induced Vascular Leakage in the Retina of Diabetic Mice.

1 reference

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Role of tissue transglutaminase-2 (TG2)-mediated aminylation in biological processes.

1 reference

12 December 2020

All disease begins in the gut: Celiac disease co-existence with SLE.

1 reference

12 December 2020

Dermatitis herpetiformis: a cutaneous manifestation of coeliac disease

1 reference

12 December 2020

Transglutaminase 2-specific coeliac disease autoantibodies induce morphological changes and signs of inflammation in the small-bowel mucosa of mice

1 reference

12 December 2020

Celiac anti-type 2 transglutaminase antibodies induce differential effects in fibroblasts from celiac disease patients and from healthy subjects.

1 reference

12 December 2020

Epitope-dependent Functional Effects of Celiac Disease Autoantibodies on Transglutaminase 2.

1 reference

12 December 2020

Tissue transglutaminase (TG2) and mitochondrial function and dysfunction

1 reference

12 December 2020

Anti-transglutaminase 6 Antibody Development in Children With Celiac Disease Correlates With Duration of Gluten Exposure

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12 December 2020

Accuracy in Diagnosis of Celiac Disease Without Biopsies in Clinical Practice

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The roles of MHC class II genes and post-translational modification in celiac disease

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Transglutaminase 6 antibodies in gluten neuropathy

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The toxic alpha-gliadin peptide 31-43 enters cells without a surface membrane receptor.

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Celiac Disease and Liver Disorders: From Putative Pathogenesis to Clinical Implications

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