Mitochondria as Cell Targets of AZT (Zidovudine) (Q62474411)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9792211 AND SRC:MED&resulttype=core&format=json

5 December 2019

review article

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title

Mitochondria as cell targets of AZT (zidovudine) (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9792211 AND SRC:MED&resulttype=core&format=json

5 December 2019

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1

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5 December 2019

Daniela Valenti

series ordinal

2

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5 December 2019

author name string

E Quagliariello

series ordinal

3

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5 December 2019

S Passarella

series ordinal

4

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5 December 2019

publication date

1 October 1998

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5 December 2019

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5 December 2019

volume

31

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5 December 2019

issue

4

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5 December 2019

page(s)

531-538

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Genotoxicity and mitochondrial damage in human lymphocytic cells chronically exposed to 3'-azido-2',3'-dideoxythymidine

5 December 2019

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Depletion of muscle mitochondrial DNA in AIDS patients with zidovudine-induced myopathy

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7 January 2021

AZT side effect on mitochondria does not depend on either inhibition of electron flow or mitochondrial uncoupling.

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Mechanisms of toxicity of 3'-azido-3'-deoxythymidine. Its interaction with adenylate kinase.

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3′-Azido-3′-deoxythymidine uptake into isolated rat liver mitochondria and impairment of ADP/ATP translocator

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The effect of zidovudine on skeletal muscle mtDNA in HIV-1 infected patients with mild or no muscle dysfunction

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Partial cytochrome c oxidase deficiency and cytoplasmic bodies in patients with zidovudine myopathy

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7 January 2021

Concurrent zidovudine-induced myopathy and hepatoxicity in patients treated for human immunodeficiency virus (HIV) infection

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7 January 2021

Hepatic Morphological alterations induced by zidovudine (ZDV) in an experimental model

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Early features of zidovudine-associated myopathy: histopathological findings and clinical correlations

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Mitochondrial myopathy caused by long-term zidovudine therapy

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Zidovudine-induced mitochondrial myopathy is associated with muscle carnitine deficiency and lipid storage

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Efficient Incorporation of Anti-HIV Deoxynucleotides by Recombinant Yeast Mitochondrial DNA Polymerase

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The efficacy of azidothymidine (AZT) in the treatment of patients with AIDS and AIDS-related complex. A double-blind, placebo-controlled trial

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Effects of 3'-azido-3'-deoxythymidine on the deoxynucleotide triphosphate pools of cultured human cells

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7 January 2021

Phosphorylation of 3'-azido-3'-deoxythymidine and selective interaction of the 5'-triphosphate with human immunodeficiency virus reverse transcriptase

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7 January 2021

Massive conversion of guanosine to 8-hydroxy-guanosine in mouse liver mitochondrial DNA by administration of azidothymidine

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7 January 2021

Major growth reduction and minor decrease in mitochondrial enzyme activity in cultured human muscle cells after exposure to zidovudine

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7 January 2021

The Friend murine erythroleukemia cell, a model system for studying the association between bone marrow toxicity induced by 3'-azido-3'-dideoxythymidine and dideoxynucleoside inhibition of mtDNA replication

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7 January 2021

Cellular targets of 3′-azido-3′-deoxythymidine: an early (non-delayed) effect on oxidative phosphorylation

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7 January 2021

The 5'-triphosphates of 3'-azido-3'-deoxythymidine and 2', 3'-dideoxynucleosides inhibit DNA polymerase gamma by different mechanisms

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7 January 2021

Ultrastructural changes associated with reduced mitochondrial DNA and impaired mitochondrial function in the presence of 2'3'-dideoxycytidine

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7 January 2021

Cardiac mitochondrial DNA polymerase-gamma is inhibited competitively and noncompetitively by phosphorylated zidovudine

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7 January 2021

The universality of bioenergetic disease and amelioration with redox therapy

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7 January 2021

Zidovudine myopathy: a distinctive disorder associated with mitochondrial dysfunction

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7 January 2021

Strategies for antiviral therapy in AIDS.

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7 January 2021

AZT causes tissue-specific inhibition of mitochondrial bioenergetic function

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7 January 2021

Mitochondrial abnormalities in human immunodeficiency virus-associated myopathy

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7 January 2021

Massive hepatic steatosis and lactic acidosis in a patient with AIDS who was receiving zidovudine

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7 January 2021

Ultrastructural characteristics and DNA immunocytochemistry in human immunodeficiency virus and zidovudine-associated myopathies

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7 January 2021

The toxicity of azidothymidine (AZT) in the treatment of patients with AIDS and AIDS-related complex. A double-blind, placebo-controlled trial

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7 January 2021

Nuclear and mitochondrial changes of co-cultivated spinal cord, spinal ganglia and muscle fibers following treatment with various doses of zidovudine

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7 January 2021

Myopathies associated with human immunodeficiency virus and zidovudine: can their effects be distinguished?

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7 January 2021

Studies on the inhibition of mitochondrial DNA replication by 3'-azido-3'-deoxythymidine and other dideoxynucleoside analogs which inhibit HIV-1 replication

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7 January 2021

Metabolic abnormalities in skeletal muscle of patients receiving zidovudine therapy observed by 31P in vivo magnetic resonance spectroscopy

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7 January 2021

Myopathy with human immunodeficiency virus type 1 (HIV-1) infection: HIV-1 or zidovudine?

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7 January 2021

AZT-induced mitochondrial myopathy

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7 January 2021

Zidovudine and dideoxynucleosides deplete wild-type mitochondrial DNA levels and increase deleted mitochondrial DNA levels in cultured Kearns-Sayre syndrome fibroblasts

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7 January 2021

31P magnetic resonance spectroscopy suggests impaired mitochondrial function in AZT-treated HIV-infected patients

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Administration of 3'-azido-3'-deoxythymidine, an inhibitor of HTLV-III/LAV replication, to patients with AIDS or AIDS-related complex

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Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9792211 AND SRC:MED&resulttype=core&format=json

5 December 2019

1 reference