Deletion of C/EBP homologous protein (Chop) in C57Bl/6 mice dissociates obesity from insulin resistance (Q61993990)

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20 January 2020

title

Deletion of C/EBP homologous protein (Chop) in C57Bl/6 mice dissociates obesity from insulin resistance (English)

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20 January 2020

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20 January 2020

author name string

M Maris

1

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20 January 2020

L Overbergh

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20 January 2020

C Gysemans

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20 January 2020

A Waget

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20 January 2020

A K Cardozo

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20 January 2020

E Verdrengh

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20 January 2020

J P M Cunha

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20 January 2020

T Gotoh

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20 January 2020

D L Eizirik

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20 January 2020

R Burcelin

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20 January 2020

C Mathieu

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20 January 2020

publication date

12 January 2012

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20 January 2020

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volume

55

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20 January 2020

issue

4

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20 January 2020

page(s)

1167-1178

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Blocking VLDL secretion causes hepatic steatosis but does not affect peripheral lipid stores or insulin sensitivity in mice

20 January 2020

cites work

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12 December 2020

Inhibition of CCR2 ameliorates insulin resistance and hepatic steatosis in db/db mice.

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Endoplasmic reticulum stress plays a central role in development of leptin resistance

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Intracellular protein therapy with SOCS3 inhibits inflammation and apoptosis

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Ectopic fat and insulin resistance

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High glucose induces dysfunction in insulin secretory cells by different pathways: a proteomic approach

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Deletion of Gab1 in the liver leads to enhanced glucose tolerance and improved hepatic insulin action

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CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum

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12 December 2020

The ER stress pathway involving CHOP is activated in the lungs of LPS-treated mice

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12 December 2020

Roles of CHOP/GADD153 in endoplasmic reticulum stress

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12 December 2020

CCAAT/Enhancer-binding protein homologous protein (CHOP) decreases bone formation and causes osteopenia

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12 December 2020

Inflammation, stress, and diabetes

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12 December 2020

Interleukin-6 (IL-6) induces insulin resistance in 3T3-L1 adipocytes and is, like IL-8 and tumor necrosis factor-alpha, overexpressed in human fat cells from insulin-resistant subjects

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12 December 2020

Oleate-induced beta cell dysfunction and apoptosis: a proteomic approach to glucolipotoxicity by an unsaturated fatty acid

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12 December 2020

Initiation and execution of lipotoxic ER stress in pancreatic beta-cells

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12 December 2020

Chop deletion reduces oxidative stress, improves beta cell function, and promotes cell survival in multiple mouse models of diabetes

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12 December 2020

IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance

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12 December 2020

Nitric oxide-induced apoptosis in pancreatic beta cells is mediated by the endoplasmic reticulum stress pathway

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12 December 2020

Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance

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12 December 2020

Transmission of endoplasmic reticulum stress and pro-inflammation from tumor cells to myeloid cells

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12 December 2020

C/EBP homologous protein is crucial for the acceleration of experimental pancreatitis

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12 December 2020

Suppressor of cytokine signaling 1 (SOCS-1) and SOCS-3 cause insulin resistance through inhibition of tyrosine phosphorylation of insulin receptor substrate proteins by discrete mechanisms

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12 December 2020

Targeted disruption of the Chop gene delays endoplasmic reticulum stress-mediated diabetes

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12 December 2020

The dual function of hepatic SOCS3 in insulin resistance in vivo.

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12 December 2020

Ectopic lipids and organ function

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12 December 2020

Endoplasmic Reticulum Stress and Inflammation in Obesity and Diabetes

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12 December 2020

Mapping of murine diabetogenic gene mody on chromosome 7 at D7Mit258 and its involvement in pancreatic islet and beta cell development during the perinatal period

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12 December 2020

MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity

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12 December 2020

Monocyte chemoattractant protein 1 in obesity and insulin resistance

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12 December 2020

Positive role of CCAAT/enhancer-binding protein homologous protein, a transcription factor involved in the endoplasmic reticulum stress response in the development of colitis

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12 December 2020

Recent advances in the relationship between obesity, inflammation, and insulin resistance.

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12 December 2020

hsp70-DnaJ chaperone pair prevents nitric oxide- and CHOP-induced apoptosis by inhibiting translocation of Bax to mitochondria

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12 December 2020

Aberrant lipid metabolism disrupts calcium homeostasis causing liver endoplasmic reticulum stress in obesity

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12 December 2020

Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes

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12 December 2020

Role of macrophage tissue infiltration in metabolic diseases.

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12 December 2020

Lipase-based quantitation of triacylglycerols in cellular lipid extracts: requirement for presence of detergent and prior separation by thin-layer chromatography

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12 December 2020

CCR2 modulates inflammatory and metabolic effects of high-fat feeding

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12 December 2020

Identification of novel stress-induced genes downstream of chop

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12 December 2020

A new enzymatic method for colorimetric determination of free fatty acids

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12 December 2020

Increase in endoplasmic reticulum stress-related proteins and genes in adipose tissue of obese, insulin-resistant individuals

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12 December 2020

C/EBP homologous protein (CHOP) is crucial for the induction of caspase-11 and the pathogenesis of lipopolysaccharide-induced inflammation

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12 December 2020

Cell signaling. Fat stress and liver resistance

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12 December 2020

Adaptive suppression of the ATF4-CHOP branch of the unfolded protein response by toll-like receptor signalling

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12 December 2020

Heterogeneous metabolic adaptation of C57BL/6J mice to high-fat diet

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12 December 2020

Increased phosphorylation of Akt substrate of 160 kDa (AS160) in rat skeletal muscle in response to insulin or contractile activity

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12 December 2020

CHOP transcription factor mediates IL-8 signaling in cystic fibrosis bronchial epithelial cells.

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12 December 2020

Hypothalamic IKKbeta/NF-kappaB and ER stress link overnutrition to energy imbalance and obesity

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12 December 2020

Ontogeny of type I and type III deiodinase activities in embryonic and posthatch chicks: relationship with changes in plasma triiodothyronine and growth hormone levels

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12 December 2020

Chop-deficient mice showed increased adiposity but no glucose intolerance

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12 December 2020

Mitochondrial reactive oxygen species promote production of proinflammatory cytokines and are elevated in TNFR1-associated periodic syndrome (TRAPS)

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12 December 2020