NLR functions beyond pathogen recognition (Q61955081)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21245903 AND SRC:MED&resulttype=core&format=json

20 January 2020

title

NLR functions beyond pathogen recognition (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21245903 AND SRC:MED&resulttype=core&format=json

20 January 2020

author

Thomas Alexander Kufer

series ordinal

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21245903 AND SRC:MED&resulttype=core&format=json

20 January 2020

author name string

Philippe J Sansonetti

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21245903 AND SRC:MED&resulttype=core&format=json

20 January 2020

language of work or name

English

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publication date

1 February 2011

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21245903 AND SRC:MED&resulttype=core&format=json

20 January 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21245903 AND SRC:MED&resulttype=core&format=json

20 January 2020

volume

12

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21245903 AND SRC:MED&resulttype=core&format=json

20 January 2020

issue

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21245903 AND SRC:MED&resulttype=core&format=json

20 January 2020

page(s)

121-128

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21245903 AND SRC:MED&resulttype=core&format=json

A novel PAAD-containing protein that modulates NF-kappa B induction by cytokines tumor necrosis factor-alpha and interleukin-1beta

20 January 2020

cites work

1 reference

12 December 2020

Epithelial NEMO links innate immunity to chronic intestinal inflammation

1 reference

12 December 2020

Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome

1 reference

12 December 2020

Elevation of neuronal expression of NAIP reduces ischemic damage in the rat hippocampus

1 reference

12 December 2020

Age-associated alteration of gene expression patterns in mouse oocytes.

1 reference

12 December 2020

Alum induces innate immune responses through macrophage and mast cell sensors, but these sensors are not required for alum to act as an adjuvant for specific immunity

1 reference

12 December 2020

Lymphoid tissue genesis induced by commensals through NOD1 regulates intestinal homeostasis.

1 reference

12 December 2020

NLRX1 is a mitochondrial NOD-like receptor that amplifies NF-kappaB and JNK pathways by inducing reactive oxygen species production

1 reference

12 December 2020

Mater, a maternal effect gene required for early embryonic development in mice

1 reference

12 December 2020

NLR family member NLRC5 is a transcriptional regulator of MHC class I genes

1 reference

12 December 2020

NLRC5 negatively regulates the NF-kappaB and type I interferon signaling pathways

1 reference

12 December 2020

A role for the human nucleotide-binding domain, leucine-rich repeat-containing family member NLRC5 in antiviral responses

1 reference

12 December 2020

IAPs: from caspase inhibitors to modulators of NF-kappaB, inflammation and cancer

1 reference

12 December 2020

Toll-like receptor 2 and NALP2 mediate induction of human beta-defensins by fusobacterium nucleatum in gingival epithelial cells

1 reference

12 December 2020

Mutations in the testis-specific NALP14 gene in men suffering from spermatogenic failure

1 reference

12 December 2020

Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria.

1 reference

12 December 2020

Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors

1 reference

12 December 2020

Nod-like proteins in immunity, inflammation and disease

1 reference

12 December 2020

Therapeutic neutralization of the NLRP1 inflammasome reduces the innate immune response and improves histopathology after traumatic brain injury

1 reference

12 December 2020

Control of infection by pyroptosis and autophagy: role of TLR and NLR.

1 reference

12 December 2020

Cutting Edge: NLRP12 Controls Dendritic and Myeloid Cell Migration To Affect Contact Hypersensitivity

1 reference

12 December 2020

IAP suppression of apoptosis involves distinct mechanisms: the TAK1/JNK1 signaling cascade and caspase inhibition

1 reference

12 December 2020

Danger signaling through the inflammasome acts as a master switch between tolerance and sensitization

1 reference

12 December 2020

Bacterial peptidoglycan triggers Candida albicans hyphal growth by directly activating the adenylyl cyclase Cyr1p

1 reference

12 December 2020

NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses

1 reference

12 December 2020

Mutations in NALP7 cause recurrent hydatidiform moles and reproductive wastage in humans

1 reference

12 December 2020

NLRX1 is a regulator of mitochondrial antiviral immunity

1 reference

12 December 2020

Nucleotide-binding oligomerization domain-2 inhibits toll-like receptor-4 signaling in the intestinal epithelium

1 reference

12 December 2020

The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer

1 reference

12 December 2020

A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1

1 reference

12 December 2020

A coding polymorphism in NALP1 confers risk for autoimmune Addison's disease and type 1 diabetes

1 reference

12 December 2020

The CATERPILLER protein monarch-1 is an antagonist of toll-like receptor-, tumor necrosis factor alpha-, and Mycobacterium tuberculosis-induced pro-inflammatory signals

1 reference

12 December 2020

The Birc1e cytosolic pattern-recognition receptor contributes to the detection and control of Legionella pneumophila infection

1 reference

12 December 2020

Modulation of adaptive immunity by different adjuvant-antigen combinations in mice lacking Nod2.

1 reference

12 December 2020

Histogenomics: association of gene expression patterns with histological parameters in kidney biopsies.

1 reference

12 December 2020

NB-LRR proteins: pairs, pieces, perception, partners, and pathways

1 reference

12 December 2020

Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants

1 reference

12 December 2020

PAN1/NALP2/PYPAF2, an inducible inflammatory mediator that regulates NF-kappaB and caspase-1 activation in macrophages

1 reference

12 December 2020

Gout-associated uric acid crystals activate the NALP3 inflammasome

1 reference

12 December 2020

XIAP mediates NOD signaling via interaction with RIP2

1 reference

12 December 2020

Targeting IL-1beta in disease; the expanding role of NLRP3 inflammasome

1 reference

12 December 2020

Control of Intestinal Homeostasis, Colitis, and Colitis-Associated Colorectal Cancer by the Inflammatory Caspases

1 reference

12 December 2020

Anti-inflammatory activity of PYNOD and its mechanism in humans and mice

1 reference

12 December 2020

Cutting edge: inflammasome activation by alum and alum's adjuvant effect are mediated by NLRP3.

1 reference

12 December 2020

MATER protein as substrate of PKCepsilon in human cumulus cells

1 reference

12 December 2020

The NACHT family - a new group of predicted NTPases implicated in apoptosis and MHC transcription activation

1 reference

12 December 2020

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

1 reference

12 December 2020

Quantitative expression of RIG-like helicase, NOD-like receptor and inflammasome-related mRNAs in humans and mice.

1 reference

12 December 2020

Thioredoxin-interacting protein links oxidative stress to inflammasome activation

1 reference

12 December 2020

Epithelial-cell-intrinsic IKK-β expression regulates intestinal immune homeostasis

1 reference

12 December 2020

Birc1e is the gene within the Lgn1 locus associated with resistance to Legionella pneumophila

1 reference

12 December 2020

Both donor and recipient NOD2/CARD15 mutations associate with transplant-related mortality and GvHD following allogeneic stem cell transplantation

1 reference

12 December 2020

Function of Nod-like receptors in microbial recognition and host defense

1 reference

12 December 2020

Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome

1 reference

12 December 2020

Nod-like receptors: sentinels at host membranes

1 reference

12 December 2020

Expression analysis of the NLRP gene family suggests a role in human preimplantation development

1 reference

12 December 2020

NALP1 in vitiligo-associated multiple autoimmune disease

1 reference

12 December 2020

PYNOD, a novel Apaf-1/CED4-like protein is an inhibitor of ASC and caspase-1.

1 reference

12 December 2020

The Nod-like receptor (NLR) family: a tale of similarities and differences

1 reference

12 December 2020

Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis

1 reference

12 December 2020

1 reference

12 December 2020

PYPAF3, a PYRIN-containing APAF-1-like protein, is a feedback regulator of caspase-1-dependent interleukin-1beta secretion

1 reference

12 December 2020

Differential regulation of caspase-1 activation, pyroptosis, and autophagy via Ipaf and ASC in Shigella-infected macrophages

1 reference

12 December 2020

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

1 reference

12 December 2020

Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes

1 reference

12 December 2020

A NOD2-NALP1 complex mediates caspase-1-dependent IL-1beta secretion in response to Bacillus anthracis infection and muramyl dipeptide

1 reference

12 December 2020

Monarch-1 suppresses non-canonical NF-kappaB activation and p52-dependent chemokine expression in monocytes.

1 reference

12 December 2020

Nuclear pore complex component MOS7/Nup88 is required for innate immunity and nuclear accumulation of defense regulators in Arabidopsis

1 reference

12 December 2020

T cells dampen innate immune responses through inhibition of NLRP1 and NLRP3 inflammasomes.

1 reference

12 December 2020

A coding variant in NLRP1 is associated with autoimmune Addison's disease.

1 reference

12 December 2020

The nucleotide-binding oligomerization domain-like receptor NLRC5 is involved in IFN-dependent antiviral immune responses

1 reference

12 December 2020

The Nlrp3 inflammasome is critical for aluminium hydroxide-mediated IL-1beta secretion but dispensable for adjuvant activity

1 reference

12 December 2020

Naip5 affects host susceptibility to the intracellular pathogen Legionella pneumophila.

1 reference

12 December 2020

Murine Nod1 but not its human orthologue mediates innate immune detection of tracheal cytotoxin

1 reference

12 December 2020

Common variants in NLRP2 and NLRP3 genes are strong prognostic factors for the outcome of HLA-identical sibling allogeneic stem cell transplantation

1 reference

12 December 2020

CATERPILLER 16.2 (CLR16.2), a novel NBD/LRR family member that negatively regulates T cell function

1 reference

12 December 2020

IL-18 production downstream of the Nlrp3 inflammasome confers protection against colorectal tumor formation

1 reference

12 December 2020

NOD-like receptors and human diseases.

1 reference

12 December 2020

Evolution and functional divergence of NLRP genes in mammalian reproductive systems

1 reference

12 December 2020

Nod1-dependent control of tumor growth

1 reference

12 December 2020

STAND, a class of P-loop NTPases including animal and plant regulators of programmed cell death: multiple, complex domain architectures, unusual phyletic patterns, and evolution by horizontal gene transfer

1 reference

12 December 2020

Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf

1 reference

12 December 2020

Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression

1 reference

12 December 2020

Colitis induced in mice with dextran sulfate sodium (DSS) is mediated by the NLRP3 inflammasome

1 reference

12 December 2020

The inflammasomes: guardians of the body

1 reference

12 December 2020

NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation

1 reference

12 December 2020

Bovine NALP5, NALP8, and NALP9 genes: assignment to a QTL region and the expression in adult tissues, oocytes, and preimplantation embryos

1 reference

12 December 2020

Insufficient evidence for association of NOD2/CARD15 or other inflammatory bowel disease-associated markers on GVHD incidence or other adverse outcomes in T-replete, unrelated donor transplantation

1 reference

12 December 2020

Germline mutation in NLRP2 (NALP2) in a familial imprinting disorder (Beckwith-Wiedemann Syndrome).

1 reference

12 December 2020

Caspase-12 modulates NOD signaling and regulates antimicrobial peptide production and mucosal immunity

1 reference

12 December 2020

Cellular inhibitors of apoptosis cIAP1 and cIAP2 are required for innate immunity signaling by the pattern recognition receptors NOD1 and NOD2.

1 reference

12 December 2020

Graft-versus-host disease: regulation by microbe-associated molecules and innate immune receptors

1 reference

12 December 2020

How the noninflammasome NLRs function in the innate immune system

1 reference

12 December 2020

Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes

1 reference

12 December 2020

Molecular identification of a danger signal that alerts the immune system to dying cells

1 reference

12 December 2020

An N-terminal addressing sequence targets NLRX1 to the mitochondrial matrix

1 reference

12 December 2020

Complementation cloning of an MHC class II transactivator mutated in hereditary MHC class II deficiency (or bare lymphocyte syndrome)

1 reference

12 December 2020

Functional screening of five PYPAF family members identifies PYPAF5 as a novel regulator of NF-kappaB and caspase-1.

1 reference

12 December 2020

Identification of oocyte-selective NLRP genes in rhesus macaque monkeys (Macaca mulatta).

1 reference

12 December 2020

Cutting edge: Monarch-1: a pyrin/nucleotide-binding domain/leucine-rich repeat protein that controls classical and nonclassical MHC class I genes

1 reference

12 December 2020

Cutting edge: CIAS1/cryopyrin/PYPAF1/NALP3/CATERPILLER 1.1 is an inducible inflammatory mediator with NF-kappa B suppressive properties

1 reference

12 December 2020

Signal transduction pathways used by NLR-type innate immune receptors

1 reference

12 December 2020

NLRC5 limits the activation of inflammatory pathways

1 reference

12 December 2020

NLRP3 inflammasome plays a key role in the regulation of intestinal homeostasis

1 reference

12 December 2020

ATG16L1 and NOD2 interact in an autophagy-dependent antibacterial pathway implicated in Crohn's disease pathogenesis

1 reference

12 December 2020

Nuclear trafficking during plant innate immunity

1 reference

12 December 2020

Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis

1 reference

12 December 2020

Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry

1 reference

12 December 2020

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

1 reference

12 December 2020

Mutations in NALP12 cause hereditary periodic fever syndromes

1 reference

12 December 2020

The NALP3 inflammasome is involved in the innate immune response to amyloid-beta

1 reference

12 December 2020

Recognition of peptidoglycan from the microbiota by Nod1 enhances systemic innate immunity

1 reference

12 December 2020

PYPAF7, a novel PYRIN-containing Apaf1-like protein that regulates activation of NF-kappa B and caspase-1-dependent cytokine processing

1 reference

12 December 2020

MHC2TA is associated with differential MHC molecule expression and susceptibility to rheumatoid arthritis, multiple sclerosis and myocardial infarction

1 reference

12 December 2020

NLRP3 plays a critical role in the development of experimental autoimmune encephalomyelitis by mediating Th1 and Th17 responses

1 reference

12 December 2020

Bcl-2 and Bcl-XL regulate proinflammatory caspase-1 activation by interaction with NALP1

1 reference

12 December 2020

Nod2 is required for the regulation of commensal microbiota in the intestine

1 reference

12 December 2020

Women heterozygous for NALP7/NLRP7 mutations are at risk for reproductive wastage: report of two novel mutations.

1 reference

12 December 2020

The NLRP3 inflammasome protects against loss of epithelial integrity and mortality during experimental colitis

1 reference

12 December 2020

NOD2 regulates hematopoietic cell function during graft-versus-host disease

1 reference

12 December 2020

NLRP2, an inhibitor of the NF-kappaB pathway, is transcriptionally activated by NF-kappaB and exhibits a nonfunctional allelic variant

1 reference

12 December 2020

The apoptosome: signalling platform of cell death

1 reference

12 December 2020

Identifiers

DOI

10.1038/NI.1985

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21245903 AND SRC:MED&resulttype=core&format=json

20 January 2020

1 reference