The role of the microbiome in NAFLD and NASH (Q61812480)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30591521 AND SRC:MED&resulttype=core&format=json

16 April 2020

review article

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title

The role of the microbiome in NAFLD and NASH (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30591521 AND SRC:MED&resulttype=core&format=json

Nonalcoholic Steatohepatitis

16 April 2020

main subject

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molecular medicine

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metabolic dysfunction–associated steatotic liver disease

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16 September 2019

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16 September 2019

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Aleksandra A Kolodziejczyk

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30591521 AND SRC:MED&resulttype=core&format=json

16 April 2020

Eran Elinav

4

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16 April 2020

author name string

Danping Zheng

2

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16 April 2020

Oren Shibolet

3

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16 April 2020

language of work or name

English

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publication date

1 February 2019

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16 September 2019

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16 April 2020

published in

EMBO Molecular Medicine

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16 September 2019

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16 April 2020

volume

11

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16 April 2020

issue

2

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Creative Commons Attribution

16 April 2020

page(s)

e9302

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copyright license

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16 September 2019

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The exogenous origin of trimethylamine in the mouse

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12 December 2020

Short-chain fatty acids in germfree mice and rats

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12 December 2020

Formation of methylamines from ingested choline and lecithin.

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12 December 2020

Kupffer cell inactivation prevents lipopolysaccharide-induced structural changes in the rat liver sinusoid: an electron-microscopic study

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12 December 2020

LPS induces NK1.1 alpha beta T cells with potent cytotoxicity in the liver of mice via production of IL-12 from Kupffer cells

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12 December 2020

Obesity increases sensitivity to endotoxin liver injury: implications for the pathogenesis of steatohepatitis

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12 December 2020

Short-chain fatty acids suppress cholesterol synthesis in rat liver and intestine.

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12 December 2020

Dietary precursors of trimethylamine in man: a pilot study

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12 December 2020

Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis.

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12 December 2020

Increased gastrointestinal ethanol production in obese mice: implications for fatty liver disease pathogenesis

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12 December 2020

Lipopolysaccharide-induced IL-18 secretion from murine Kupffer cells independently of myeloid differentiation factor 88 that is critically involved in induction of production of IL-12 and IL-1beta

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12 December 2020

Long-Term treatment with cisapride and antibiotics in liver cirrhosis: effect on small intestinal motility, bacterial overgrowth, and liver function

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12 December 2020

The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids

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12 December 2020

Biosynthesis of phosphatidylcholine in bacteria.

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12 December 2020

Toll-like receptor 4 mediates inflammatory signaling by bacterial lipopolysaccharide in human hepatic stellate cells

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12 December 2020

The gut microbiota as an environmental factor that regulates fat storage

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12 December 2020

Cutting edge: TLR4 activation mediates liver ischemia/reperfusion inflammatory response via IFN regulatory factor 3-dependent MyD88-independent pathway

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12 December 2020

Development and functional consequences of LPS tolerance in sinusoidal endothelial cells of the liver

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12 December 2020

Bile salt biotransformations by human intestinal bacteria

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12 December 2020

How different is the dietary pattern in non-alcoholic steatohepatitis patients?

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12 December 2020

Pattern recognition receptors: a contemporary view on liver diseases.

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12 December 2020

Metabolic profiling reveals a contribution of gut microbiota to fatty liver phenotype in insulin-resistant mice

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12 December 2020

Metabolic endotoxemia initiates obesity and insulin resistance

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12 December 2020

Toll-like receptor-4 signaling and Kupffer cells play pivotal roles in the pathogenesis of non-alcoholic steatohepatitis

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12 December 2020

THE PREVENTION BY CHOLINE OF LIVER CIRRHOSIS IN RATS ON HIGH FAT, LOW PROTEIN DIETS.

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12 December 2020

TLR4 enhances TGF-beta signaling and hepatic fibrosis

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12 December 2020

Non alcoholic fatty liver disease: treatment with soluble fibres

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12 December 2020

Antibiotics protect against fructose-induced hepatic lipid accumulation in mice: role of endotoxin

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12 December 2020

Bile acid levels are increased in the liver of patients with steatohepatitis

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12 December 2020

Physiological, pathological, and therapeutic implications of zonulin-mediated intestinal barrier modulation: living life on the edge of the wall

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12 December 2020

Effects of the gut microbiota on host adiposity are modulated by the short-chain fatty-acid binding G protein-coupled receptor, Gpr41

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12 December 2020

Increased intestinal permeability and tight junction alterations in nonalcoholic fatty liver disease.

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12 December 2020

Inflammasome-mediated regulation of hepatic stellate cells

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12 December 2020

Microbiota and SCFA in lean and overweight healthy subjects

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12 December 2020

Toll-like receptor 4 is involved in the development of fructose-induced hepatic steatosis in mice.

1 reference

12 December 2020

Tlr2 is critical for diet-induced metabolic syndrome in a murine model.

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12 December 2020

Intestinal mucosal barrier function in health and disease

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12 December 2020

Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43

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12 December 2020

Bariatric surgery for non-alcoholic steatohepatitis in obese patients

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12 December 2020

Metabolic syndrome and altered gut microbiota in mice lacking Toll-like receptor 5

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12 December 2020

Toll-like receptor 9 promotes steatohepatitis by induction of interleukin-1beta in mice

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12 December 2020

Elevated endotoxin levels in non-alcoholic fatty liver disease

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12 December 2020

Toll-like receptor 2-deficient mice are protected from insulin resistance and beta cell dysfunction induced by a high-fat diet.

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12 December 2020

Toll-like receptor-2 deficiency enhances non-alcoholic steatohepatitis

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12 December 2020

Germ-free C57BL/6J mice are resistant to high-fat-diet-induced insulin resistance and have altered cholesterol metabolism.

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12 December 2020

The role of the gut microbiota in nonalcoholic fatty liver disease

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12 December 2020

Association between composition of the human gastrointestinal microbiome and development of fatty liver with choline deficiency

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12 December 2020

The bile acid membrane receptor TGR5 as an emerging target in metabolism and inflammation

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12 December 2020

The role of lipopolysaccharide/toll-like receptor 4 signaling in chronic liver diseases.

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12 December 2020

Energy-balance studies reveal associations between gut microbes, caloric load, and nutrient absorption in humans

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12 December 2020

Human nutrition, the gut microbiome and the immune system

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12 December 2020

DSS induced colitis increases portal LPS levels and enhances hepatic inflammation and fibrogenesis in experimental NASH

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12 December 2020

Intestinal mucosal adherence and translocation of commensal bacteria at the early onset of type 2 diabetes: molecular mechanisms and probiotic treatment.

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12 December 2020

CytochromeP-450 CYP2E1 knockout mice are protected against high-fat diet-induced obesity and insulin resistance

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12 December 2020

Oral administration of immunoglobulin G-enhanced colostrum alleviates insulin resistance and liver injury and is associated with alterations in natural killer T cells

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12 December 2020

Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity

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12 December 2020

Nutrition, intestinal permeability, and blood ethanol levels are altered in patients with nonalcoholic fatty liver disease (NAFLD)

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12 December 2020

Phosphatidylcholine biosynthesis and function in bacteria.

1 reference

12 December 2020

Toll-like receptor 2 and palmitic acid cooperatively contribute to the development of nonalcoholic steatohepatitis through inflammasome activation in mice

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12 December 2020

Characterization of gut microbiomes in nonalcoholic steatohepatitis (NASH) patients: a connection between endogenous alcohol and NASH.

1 reference

12 December 2020

Microbial conversion of choline to trimethylamine requires a glycyl radical enzyme

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12 December 2020

Intestinal microbiota determines development of non-alcoholic fatty liver disease in mice.

1 reference

12 December 2020

Alleviation of insulin resistance and liver damage by oral administration of Imm124-E is mediated by increased Tregs and associated with increased serum GLP-1 and adiponectin: results of a phase I/II clinical trial in NASH

1 reference

12 December 2020

Olfactory receptor responding to gut microbiota-derived signals plays a role in renin secretion and blood pressure regulation

1 reference

12 December 2020

Fatty liver accompanies an increase in lactobacillus species in the hind gut of C57BL/6 mice fed a high-fat diet

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12 December 2020

Nonalcoholic fatty liver disease is associated with lower hepatic and erythrocyte ratios of phosphatidylcholine to phosphatidylethanolamine

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12 December 2020

Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis

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12 December 2020

The gut microbiota suppresses insulin-mediated fat accumulation via the short-chain fatty acid receptor GPR43.

1 reference

12 December 2020

A systematic review of follow-up biopsies reveals disease progression in patients with non-alcoholic fatty liver

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12 December 2020

Cirrhosis, bile acids and gut microbiota: unraveling a complex relationship.

1 reference

12 December 2020

Gut microbiota from twins discordant for obesity modulate metabolism in mice

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12 December 2020

Intestinal epithelial cells: regulators of barrier function and immune homeostasis

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12 December 2020

Specialized metabolites from the microbiome in health and disease

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12 December 2020

Nonalcoholic steatohepatitis is the second leading etiology of liver disease among adults awaiting liver transplantation in the United States

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12 December 2020

Altered gut microbial energy and metabolism in children with non-alcoholic fatty liver disease

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12 December 2020

Intestinal microbiota composition modulates choline bioavailability from diet and accumulation of the proatherogenic metabolite trimethylamine-N-oxide

1 reference

12 December 2020

Metabolite-sensing receptors GPR43 and GPR109A facilitate dietary fibre-induced gut homeostasis through regulation of the inflammasome.

1 reference

12 December 2020

Characterization and detection of a widely distributed gene cluster that predicts anaerobic choline utilization by human gut bacteria

1 reference

12 December 2020

Dietary gut microbial metabolites, short-chain fatty acids, and host metabolic regulation

1 reference

12 December 2020

The role of microbial amino acid metabolism in host metabolism

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12 December 2020

Efficacy of rifaximin on circulating endotoxins and cytokines in patients with nonalcoholic fatty liver disease.

1 reference

12 December 2020

Hepatic TLR4 signaling in obese NAFLD

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12 December 2020

Altered Bile Acid Metabolome in Patients with Nonalcoholic Steatohepatitis

1 reference

12 December 2020

Hepatic Injury in Nonalcoholic Steatohepatitis Contributes to Altered Intestinal Permeability

1 reference

12 December 2020

Personalized Nutrition by Prediction of Glycemic Responses.

1 reference

12 December 2020

The severity of nonalcoholic fatty liver disease is associated with gut dysbiosis and shift in the metabolic function of the gut microbiota

1 reference

12 December 2020

Global epidemiology of nonalcoholic fatty liver disease-Meta-analytic assessment of prevalence, incidence, and outcomes.

1 reference

12 December 2020

Hepatocyte mitochondrial DNA drives nonalcoholic steatohepatitis by activation of TLR9

1 reference

12 December 2020

Lack of hepcidin expression attenuates steatosis and causes fibrosis in the liver

1 reference

12 December 2020

Antibiotic perturbation of the murine gut microbiome enhances the adiposity, insulin resistance, and liver disease associated with high-fat diet

1 reference

12 December 2020

The Natural Course of Non-Alcoholic Fatty Liver Disease

1 reference

12 December 2020

Loss of Junctional Adhesion Molecule A Promotes Severe Steatohepatitis in Mice on a Diet High in Saturated Fat, Fructose, and Cholesterol

1 reference

12 December 2020

Bile acids and nonalcoholic fatty liver disease: Molecular insights and therapeutic perspectives

1 reference

12 December 2020

Changes in blood microbiota profiles associated with liver fibrosis in obese patients: A pilot analysis

1 reference

12 December 2020

The Liver at the Nexus of Host-Microbial Interactions

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12 December 2020

Sodium butyrate protects mice from the development of the early signs of non-alcoholic fatty liver disease: role of melatonin and lipid peroxidation

1 reference

12 December 2020

Persistent microbiome alterations modulate the rate of post-dieting weight regain

1 reference

12 December 2020

Soluble Fibre Meal Challenge Reduces Airway Inflammation and Expression of GPR43 and GPR41 in Asthma.

1 reference

12 December 2020

Hepatocyte Toll-Like Receptor 5 Promotes Bacterial Clearance and Protects Mice Against High-Fat Diet-Induced Liver Disease

1 reference

12 December 2020

Sodium butyrate attenuates high-fat diet-induced steatohepatitis in mice by improving gut microbiota and gastrointestinal barrier

1 reference

12 December 2020

Dysbiosis and the immune system

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12 December 2020

Gut Microbiome-Based Metagenomic Signature for Non-invasive Detection of Advanced Fibrosis in Human Nonalcoholic Fatty Liver Disease

1 reference

12 December 2020

Total fecal microbiota transplantation alleviates high-fat diet-induced steatohepatitis in mice via beneficial regulation of gut microbiota

1 reference

12 December 2020

How to Approach a Patient With Nonalcoholic Fatty Liver Disease.

1 reference

12 December 2020

TLR9 is up-regulated in human and murine NASH: pivotal role in inflammatory recruitment and cell survival.

1 reference

12 December 2020

The Diagnosis and Management of Nonalcoholic Fatty Liver Disease: Practice Guidance from the American Association for the Study of Liver Diseases.

1 reference

12 December 2020

NLRP3 Deletion Inhibits the Non-alcoholic Steatohepatitis Development and Inflammation in Kupffer Cells Induced by Palmitic Acid

1 reference

12 December 2020

Altered amino acid concentrations in NAFLD: Impact of obesity and insulin resistance

1 reference

12 December 2020

Global burden of NAFLD and NASH: trends, predictions, risk factors and prevention

1 reference

12 December 2020

Gut Microbiota and Nonalcoholic Fatty Liver Disease: Insights on Mechanisms and Therapy

1 reference

12 December 2020

Restoration of A Healthy Intestinal Microbiota Normalizes Portal Hypertension In A Rat Model of Nonalcoholic Steatohepatitis.

1 reference

12 December 2020

Nonalcoholic Fatty Liver Disease Is Exacerbated in High-Fat Diet-Fed Gnotobiotic Mice by Colonization with the Gut Microbiota from Patients with Nonalcoholic Steatohepatitis

1 reference

12 December 2020

Hepatocyte toll-like receptor 4 mediates lipopolysaccharide-induced hepcidin expression

1 reference

12 December 2020

Small Intestine Microbiota Regulate Host Digestive and Absorptive Adaptive Responses to Dietary Lipids

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12 December 2020

Bile acid regulation: A novel therapeutic strategy in non-alcoholic fatty liver disease

1 reference

12 December 2020

Lack of liver steatosis in germ-free mice following hypercaloric diets

1 reference

12 December 2020

Molecular phenomics and metagenomics of hepatic steatosis in non-diabetic obese women

1 reference

12 December 2020

Sodium Butyrate Ameliorates High-Fat-Diet-Induced Non-alcoholic Fatty Liver Disease through Peroxisome Proliferator-Activated Receptor α-Mediated Activation of β Oxidation and Suppression of Inflammation

1 reference

12 December 2020

Genetically Obese Human Gut Microbiota Induces Liver Steatosis in Germ-Free Mice Fed on Normal Diet

1 reference

12 December 2020

Personalized Gut Mucosal Colonization Resistance to Empiric Probiotics Is Associated with Unique Host and Microbiome Features

1 reference

12 December 2020

Post-Antibiotic Gut Mucosal Microbiome Reconstitution Is Impaired by Probiotics and Improved by Autologous FMT

1 reference

12 December 2020

Identifiers

DOI

10.15252/EMMM.201809302

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30591521 AND SRC:MED&resulttype=core&format=json

16 April 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30591521 AND SRC:MED&resulttype=core&format=json

16 April 2020

PubMed publication ID

30591521

1 reference