Reversible contraction by looping of the Tcra and Tcrb loci in rearranging thymocytes (Q61032257)

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26 December 2019

title

Reversible contraction by looping of the Tcra and Tcrb loci in rearranging thymocytes (English)

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26 December 2019

Wouter de Laat

5

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26 December 2019

Meinrad Busslinger

6

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26 December 2019

author name string

Ramiro Gisler

2

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Maria Novatchkova

3

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26 December 2019

Deborah Farmer

4

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language of work or name

English

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publication date

4 March 2007

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volume

8

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issue

4

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page(s)

378-387

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The mechanism and regulation of chromosomal V(D)J recombination

26 December 2019

cites work

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Developmentally controlled and tissue-specific expression of unrearranged VH gene segments

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Pax5 induces V-to-DJ rearrangements and locus contraction of the immunoglobulin heavy-chain gene

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Locus 'decontraction' and centromeric recruitment contribute to allelic exclusion of the immunoglobulin heavy-chain gene

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Visualization of looping involving the immunoglobulin heavy-chain locus in developing B cells

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The mouse (Mus musculus) T cell receptor alpha (TRA) and delta (TRD) variable genes

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Enforcing order within a complex locus: current perspectives on the control of V(D)J recombination at the murine T-cell receptor alpha/delta locus

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Nonequivalent nuclear location of immunoglobulin alleles in B lymphocytes.

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Capturing chromosome conformation

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Looping and interaction between hypersensitive sites in the active beta-globin locus

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3C technology: analyzing the spatial organization of genomic loci in vivo.

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Restoration of T cell development in RAG-2-deficient mice by functional TCR transgenes.

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Epigenetic ontogeny of the Igk locus during B cell development

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Gene-targeted deletion and replacement mutations of the T-cell receptor beta-chain enhancer: the role of enhancer elements in controlling V(D)J recombination accessibility.

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Control of V(D)J recombinational accessibility of the D beta 1 gene segment at the TCR beta locus by a germline promoter

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Chromatin remodeling by the T cell receptor (TCR)-beta gene enhancer during early T cell development: Implications for the control of TCR-beta locus recombination

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Regulation of TCR delta and alpha repertoires by local and long-distance control of variable gene segment chromatin structure

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Regulation of TCRbeta gene assembly by a promoter/enhancer holocomplex

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Comparative genomics of the human and mouse T cell receptor loci

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Multiple interactions between regulatory regions are required to stabilize an active chromatin hub.

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Hypersensitive site 7 of the TH2 locus control region is essential for expressing TH2 cytokine genes and for long-range intrachromosomal interactions

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The T-cell receptor beta variable gene promoter is required for efficient V beta rearrangement but not allelic exclusion

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7 January 2021

Two waves of recombinase gene expression in developing thymocytes

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7 January 2021

Assessing the role of the T cell receptor beta gene enhancer in regulating coding joint formation during V(D)J recombination

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Transient IL-7/IL-7R signaling provides a mechanism for feedback inhibition of immunoglobulin heavy chain gene rearrangements

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Differential regulation between gene expression and histone H3 acetylation in the variable regions of the TCRbeta locus

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Regulation of T cell receptor beta allelic exclusion at a level beyond accessibility

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Distinct control of the frequency and allelic exclusion of the V beta gene rearrangement at the TCR beta locus

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7 January 2021

Increase of TCR V beta accessibility within E beta regulatory region influences its recombination frequency but not allelic exclusion.

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Asynchronous replication and allelic exclusion in the immune system

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7 January 2021

Variegated transcriptional activation of the immunoglobulin kappa locus in pre-b cells contributes to the allelic exclusion of light-chain expression

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7 January 2021

Assembly of productive T cell receptor delta variable region genes exhibits allelic inclusion

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7 January 2021

Expression of two T cell receptor alpha chains: dual receptor T cells

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7 January 2021

Quantitative and qualitative changes in V-J alpha rearrangements during mouse thymocytes differentiation: implication for a limited T cell receptor alpha chain repertoire

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7 January 2021

Ezh2 controls B cell development through histone H3 methylation and Igh rearrangement.

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7 January 2021

Chromatin compaction by a polycomb group protein complex

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7 January 2021

Polycomb group protein ezh2 controls actin polymerization and cell signaling.

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7 January 2021

Inactivation of Notch1 impairs VDJbeta rearrangement and allows pre-TCR-independent survival of early alpha beta Lineage Thymocytes.

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7 January 2021

Critical functions for c-Myb at three checkpoints during thymocyte development

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7 January 2021

T cell receptor (TcR) beta chain transgenic mice: studies on allelic exclusion and on the TcR gamma/delta population

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7 January 2021

CD4 T cell tolerance to human C-reactive protein, an inducible serum protein, is mediated by medullary thymic epithelium

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7 January 2021

Identifiers

DOI

10.1038/NI1448

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17334367 AND SRC:MED&resulttype=core&format=json

26 December 2019

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