Modulating T Cell Responses via Autophagy: The Intrinsic Influence Controlling the Function of Both Antigen-Presenting Cells and T Cells (Q60954864)

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17 April 2020

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Modulating T Cell Responses via Autophagy: The Intrinsic Influence Controlling the Function of Both Antigen-Presenting Cells and T Cells (English)

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Seth D Merkley

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Cameron J Chock

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Xuexian O Yang

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James Harris

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14 December 2018

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Frontiers in Immunology

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20 November 2019

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Creative Commons Attribution 4.0 International

17 April 2020

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4 references

20 November 2019

26 August 2020

12 September 2020

IL-12 induces the production of IFN-gamma by neonatal human CD4 T cells.

2 November 2020

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12 December 2020

Neutrophil recruitment by human IL-17 via C-X-C chemokine release in the airways

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12 December 2020

Role of costimulation in the induction of the IL-12/IL-12 receptor pathway and the development of autoimmunity

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12 December 2020

IL-12 synergizes with IL-18 or IL-1beta for IFN-gamma production from human T cells

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12 December 2020

Interleukin-7 mediates the homeostasis of naïve and memory CD8 T cells in vivo

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12 December 2020

Interleukin-1beta costimulates interferon-gamma production by human natural killer cells

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12 December 2020

Cutting Edge: Intravenous Soluble Antigen Is Presented to CD4 T Cells by CD8- Dendritic Cells, but Cross-Presented to CD8 T Cells by CD8 Dendritic Cells

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12 December 2020

TCR engagement in the absence of cell cycle progression leads to T cell anergy independent of p27(Kip1).

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12 December 2020

Impaired resistance and enhanced pathology during infection with a noninvasive, attaching-effacing enteric bacterial pathogen, Citrobacter rodentium, in mice lacking IL-12 or IFN-gamma

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12 December 2020

Modulation of T-lymphocyte development, growth and cell size by the Myc antagonist and transcriptional repressor Mad1.

1 reference

12 December 2020

Constitutive versus activation-dependent cross-presentation of immune complexes by CD8( ) and CD8(-) dendritic cells in vivo

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12 December 2020

Projection of an immunological self shadow within the thymus by the aire protein

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12 December 2020

Association of a polymorphism in the P2X7 gene with tuberculosis in a Gambian population

1 reference

12 December 2020

A role for CD28 in lymphopenia-induced proliferation of CD4 T cells

1 reference

12 December 2020

A distinct region of the murine IFN-gamma promoter is hypomethylated from early T cell development through mature naive and Th1 cell differentiation, but is hypermethylated in Th2 cells

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12 December 2020

Endogenous MHC class II processing of a viral nuclear antigen after autophagy.

1 reference

12 December 2020

Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages

1 reference

12 December 2020

Autophagy promotes MHC class II presentation of peptides from intracellular source proteins

1 reference

12 December 2020

Gout-associated uric acid crystals activate the NALP3 inflammasome

1 reference

12 December 2020

STAT3 and NF-kappaB signal pathway is required for IL-23-mediated IL-17 production in spontaneous arthritis animal model IL-1 receptor antagonist-deficient mice

1 reference

12 December 2020

c-Myc mediates pre-TCR-induced proliferation but not developmental progression

1 reference

12 December 2020

Oxidative metabolism and PGC-1beta attenuate macrophage-mediated inflammation

1 reference

12 December 2020

A crucial role for interleukin (IL)-1 in the induction of IL-17-producing T cells that mediate autoimmune encephalomyelitis.

1 reference

12 December 2020

Human IRGM induces autophagy to eliminate intracellular mycobacteria

1 reference

12 December 2020

IRF-1 deficiency skews the differentiation of dendritic cells toward plasmacytoid and tolerogenic features.

1 reference

12 December 2020

Autophagy is induced in CD4 T cells and important for the growth factor-withdrawal cell death

1 reference

12 December 2020

A polymorphism in the P2X7 gene increases susceptibility to extrapulmonary tuberculosis

1 reference

12 December 2020

Role of IL-17 and regulatory T lymphocytes in a systemic autoimmune disease

1 reference

12 December 2020

Antigen-loading compartments for major histocompatibility complex class II molecules continuously receive input from autophagosomes

1 reference

12 December 2020

A critical role for the autophagy gene Atg5 in T cell survival and proliferation

1 reference

12 December 2020

A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1

1 reference

12 December 2020

Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis

1 reference

12 December 2020

Therapeutic effect of a new immunosuppressive agent, everolimus, on interleukin-10 gene-deficient mice with colitis

1 reference

12 December 2020

Risks and benefits of biologic therapy for inflammatory bowel diseases

1 reference

12 December 2020

Association analysis of genetic variants in IL23R, ATG16L1 and 5p13.1 loci with Crohn's disease in Japanese patients

1 reference

12 December 2020

Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility

1 reference

12 December 2020

IL-15 is required for sustained lymphopenia-driven proliferation and accumulation of CD8 T cells

1 reference

12 December 2020

T helper 2 cytokines inhibit autophagic control of intracellular Mycobacterium tuberculosis.

1 reference

12 December 2020

IL23R R381Q and ATG16L1 T300A Are Strongly Associated With Crohn's Disease in a Study of New Zealand Caucasians With Inflammatory Bowel Disease

1 reference

12 December 2020

Homeostasis and effector function of lymphopenia-induced "memory-like" T cells in constitutively T cell-depleted mice

1 reference

12 December 2020

Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica

1 reference

12 December 2020

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

1 reference

12 December 2020

Macrophage migration inhibitory factor stimulates interleukin-17 expression and production in lymph node cells

1 reference

12 December 2020

Autophagy in thymic epithelium shapes the T-cell repertoire and is essential for tolerance

1 reference

12 December 2020

Cutting edge: IL-1 controls the IL-23 response induced by gliadin, the etiologic agent in celiac disease

1 reference

12 December 2020

Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production

1 reference

12 December 2020

A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells

1 reference

12 December 2020

Th1-Th2 polarisation and autophagy in the control of intracellular mycobacteria by macrophages.

1 reference

12 December 2020

Adenosine 5'-monophosphate-activated protein kinase promotes macrophage polarization to an anti-inflammatory functional phenotype

1 reference

12 December 2020

Elevated ATG5 expression in autoimmune demyelination and multiple sclerosis

1 reference

12 December 2020

Interferon-inducible immunity-related GTPase Irgm1 regulates IFN gamma-dependent host defense, lymphocyte survival and autophagy

1 reference

12 December 2020

Uptake of particulate vaccine adjuvants by dendritic cells activates the NALP3 inflammasome

1 reference

12 December 2020

A common role for Atg16L1, Atg5 and Atg7 in small intestinal Paneth cells and Crohn disease

1 reference

12 December 2020

Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn's disease

1 reference

12 December 2020

IFN-gamma-inducible Irga6 mediates host resistance against Chlamydia trachomatis via autophagy

1 reference

12 December 2020

Autophagy enhances the efficacy of BCG vaccine by increasing peptide presentation in mouse dendritic cells

1 reference

12 December 2020

Autophagy is essential for mitochondrial clearance in mature T lymphocytes

1 reference

12 December 2020

Interleukin-1 and IL-23 induce innate IL-17 production from gammadelta T cells, amplifying Th17 responses and autoimmunity.

1 reference

12 December 2020

Autophagy is activated by TGF-beta and potentiates TGF-beta-mediated growth inhibition in human hepatocellular carcinoma cells.

1 reference

12 December 2020

Autophagic compartments gain access to the MHC class II compartments in thymic epithelium.

1 reference

12 December 2020

Delivery of cytosolic components by autophagic adaptor protein p62 endows autophagosomes with unique antimicrobial properties.

1 reference

12 December 2020

Genome-wide association study for ulcerative colitis identifies risk loci at 7q22 and 22q13 (IL17REL).

1 reference

12 December 2020

Gamma interferon produced by antigen-specific CD4 T cells regulates the mucosal immune responses to Citrobacter rodentium infection

1 reference

12 December 2020

Toll-like receptor-induced changes in glycolytic metabolism regulate dendritic cell activation

1 reference

12 December 2020

Infliximab, azathioprine, or combination therapy for Crohn's disease

1 reference

12 December 2020

Substrate fate in activated macrophages: a comparison between innate, classic, and alternative activation

1 reference

12 December 2020

HIV-1 inhibits autophagy in bystander macrophage/monocytic cells through Src-Akt and STAT3.

1 reference

12 December 2020

Th17 plasticity in human autoimmune arthritis is driven by the inflammatory environment

1 reference

12 December 2020

Identification of small molecules enhancing autophagic function from drug network analysis

1 reference

12 December 2020

Macroautophagy regulates energy metabolism during effector T cell activation

1 reference

12 December 2020

Study of the common genetic background for rheumatoid arthritis and systemic lupus erythematosus

1 reference

12 December 2020

IL-10 inhibits the starvation induced autophagy in macrophages via class I phosphatidylinositol 3-kinase (PI3K) pathway

1 reference

12 December 2020

A role for mitochondria in NLRP3 inflammasome activation

1 reference

12 December 2020

Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome

1 reference

12 December 2020

Autophagy Regulates Endoplasmic Reticulum Homeostasis and Calcium Mobilization in T Lymphocytes

1 reference

12 December 2020

Control of autophagy with small molecules

1 reference

12 December 2020

Autophagy Controls IL-1β Secretion by Targeting Pro-IL-1β for Degradation

1 reference

12 December 2020

A Role for Autophagic Protein Beclin 1 Early in Lymphocyte Development

1 reference

12 December 2020

Autophagy in immunity and inflammation

1 reference

12 December 2020

A synonymous variant in IRGM alters a binding site for miR-196 and causes deregulation of IRGM-dependent xenophagy in Crohn's disease

1 reference

12 December 2020

Temporal Regulation of Intracellular Organelle Homeostasis in T Lymphocytes by Autophagy

1 reference

12 December 2020

Autophagosomal IkappaB alpha degradation plays a role in the long term control of tumor necrosis factor-alpha-induced nuclear factor-kappaB (NF-kappaB) activity.

1 reference

12 December 2020

Genetic variation in the autophagy gene ULK1 and risk of Crohn's disease.

1 reference

12 December 2020

Genetic association of PRDM1-ATG5 intergenic region and autophagy with systemic lupus erythematosus in a Chinese population

1 reference

12 December 2020

Autophagy promotes T-cell survival through degradation of proteins of the cell death machinery

1 reference

12 December 2020

Normal T cell homeostasis: the conversion of naive cells into memory-phenotype cells

1 reference

12 December 2020

The -1082A/G polymorphism in the Interleukin-10 gene and the risk of rheumatoid arthritis: a meta-analysis

1 reference

12 December 2020

Autophagy and cytokines

1 reference

12 December 2020

IL-1α and IL-1β Recruit Different Myeloid Cells and Promote Different Stages of Sterile Inflammation

1 reference

12 December 2020

Aerobic glycolysis: meeting the metabolic requirements of cell proliferation

1 reference

12 December 2020

Granzyme B-dependent proteolysis acts as a switch to enhance the proinflammatory activity of IL-1α.

1 reference

12 December 2020

The Class III Kinase Vps34 Promotes T Lymphocyte Survival through Regulating IL-7Rα Surface Expression

1 reference

12 December 2020

Autophagy-based unconventional secretory pathway for extracellular delivery of IL-1β

1 reference

12 December 2020

Microautophagy: lesser-known self-eating

1 reference

12 December 2020

Interferon Regulatory Factor-1 Regulates the Autophagic Response in LPS-Stimulated Macrophages through Nitric Oxide

1 reference

12 December 2020

The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation

1 reference

12 December 2020

Induction of autophagy is essential for monocyte-macrophage differentiation

1 reference

12 December 2020

Splenocyte Apoptosis and Autophagy Is Mediated by Interferon Regulatory Factor 1 During Murine Endotoxemia

1 reference

12 December 2020

Activation of autophagy by inflammatory signals limits IL-1β production by targeting ubiquitinated inflammasomes for destruction

1 reference

12 December 2020

Identification of autophagosome-associated proteins and regulators by quantitative proteomic analysis and genetic screens.

1 reference

12 December 2020

Autophagy inhibition promotes defective neosynthesized proteins storage in ALIS, and induces redirection toward proteasome processing and MHCI-restricted presentation

1 reference

12 December 2020

Autophagy is required for CSF-1-induced macrophagic differentiation and acquisition of phagocytic functions.

1 reference

12 December 2020

Inhibiting systemic autophagy during interleukin 2 immunotherapy promotes long-term tumor regression.

1 reference

12 December 2020

Macrophage migration inhibitory factor induces autophagy via reactive oxygen species generation

1 reference

12 December 2020

IFN-γ elicits macrophage autophagy via the p38 MAPK signaling pathway.

1 reference

12 December 2020

Chaperone-mediated autophagy: a unique way to enter the lysosome world

1 reference

12 December 2020

IL-12 family cytokines: immunological playmakers

1 reference

12 December 2020

Extracellular M. tuberculosis DNA Targets Bacteria for Autophagy by Activating the Host DNA-Sensing Pathway

1 reference

12 December 2020

Autophagy regulates IL-23 secretion and innate T cell responses through effects on IL-1 secretion

1 reference

12 December 2020

Autophagy regulates TNFα-mediated joint destruction in experimental arthritis.

1 reference

12 December 2020

Autophagy protects against active tuberculosis by suppressing bacterial burden and inflammation

1 reference

12 December 2020

Pathways of antigen processing

1 reference

12 December 2020

AMPKα1: a glucose sensor that controls CD8 T-cell memory

1 reference

12 December 2020

Metabolism of inflammation limited by AMPK and pseudo-starvation

1 reference

12 December 2020

Human type 1 innate lymphoid cells accumulate in inflamed mucosal tissues

1 reference

12 December 2020

Macroautophagy substrates are loaded onto MHC class II of medullary thymic epithelial cells for central tolerance

1 reference

12 December 2020

Metabolic control of the Treg/Th17 axis

1 reference

12 December 2020

From Identification to Characterization of the Multiple Sclerosis Susceptibility Gene CLEC16A.

1 reference

12 December 2020

Intraepithelial type 1 innate lymphoid cells are a unique subset of IL-12- and IL-15-responsive IFN-γ-producing cells

1 reference

12 December 2020

Autophagy and IL-1 Family Cytokines

1 reference

12 December 2020

Role of Th17 cells in the pathogenesis of CNS inflammatory demyelination

1 reference

12 December 2020

Posttranscriptional control of T cell effector function by aerobic glycolysis

1 reference

12 December 2020

The relationship between metabolism and the autophagy machinery during the innate immune response

1 reference

12 December 2020

Intestinal epithelial autophagy is essential for host defense against invasive bacteria

1 reference

12 December 2020

Autophagy as an immune effector against tuberculosis

1 reference

12 December 2020

A deficiency in the autophagy gene Atg16L1 enhances resistance to enteric bacterial infection

1 reference

12 December 2020

Vedolizumab as induction and maintenance therapy for ulcerative colitis

1 reference

12 December 2020

Vedolizumab as induction and maintenance therapy for Crohn's disease

1 reference

12 December 2020

Phosphofructokinase deficiency impairs ATP generation, autophagy, and redox balance in rheumatoid arthritis T cells

1 reference

12 December 2020

Autophagy in infection, inflammation, and immunity

1 reference

12 December 2020

STAT3 as a new autophagy regulator

1 reference

12 December 2020

Recent advances in inflammatory bowel disease: mucosal immune cells in intestinal inflammation

1 reference

12 December 2020

Recent insights on the putative role of autophagy in autoimmune diseases.

1 reference

12 December 2020

Autophagy proteins control goblet cell function by potentiating reactive oxygen species production

1 reference

12 December 2020

T cell exit from quiescence and differentiation into Th2 cells depend on Raptor-mTORC1-mediated metabolic reprogramming

1 reference

12 December 2020

Association between polymorphisms in the promoter region of interleukin-10 and susceptibility to inflammatory bowel disease

1 reference

12 December 2020

Activation of the NLRP1b inflammasome independently of ASC-mediated caspase-1 autoproteolysis and speck formation

1 reference

12 December 2020

Combination therapy with infliximab and azathioprine is superior to monotherapy with either agent in ulcerative colitis

1 reference

12 December 2020

TLR-driven early glycolytic reprogramming via the kinases TBK1-IKKɛ supports the anabolic demands of dendritic cell activation

1 reference

12 December 2020

Autophagy--a key player in cellular and body metabolism

1 reference

12 December 2020

Regulation of SIV antigen-specific CD4 T cellular immunity via autophagosome-mediated MHC II molecule-targeting antigen presentation in mice

1 reference

12 December 2020

Cytokines in inflammatory bowel disease

1 reference

12 December 2020

Interleukin-10 receptor signaling in innate immune cells regulates mucosal immune tolerance and anti-inflammatory macrophage function

1 reference

12 December 2020

Macrophage-restricted interleukin-10 receptor deficiency, but not IL-10 deficiency, causes severe spontaneous colitis

1 reference

12 December 2020

Macrophages in intestinal homeostasis and inflammation

1 reference

12 December 2020

Integrating canonical and metabolic signalling programmes in the regulation of T cell responses

1 reference

12 December 2020

Mechanistic target of rapamycin inhibition extends cellular lifespan in dendritic cells by preserving mitochondrial function.

1 reference

12 December 2020

mTOR and autophagy: a dynamic relationship governed by nutrients and energy.

1 reference

12 December 2020

mTOR- and HIF-1α-mediated aerobic glycolysis as metabolic basis for trained immunity.

1 reference

12 December 2020

Inflammasome activation leads to Caspase-1-dependent mitochondrial damage and block of mitophagy

1 reference

12 December 2020

Autophagy is essential for effector CD8( ) T cell survival and memory formation

1 reference

12 December 2020

Dendritic cell IL-1α and IL-1β are polyubiquitinated and degraded by the proteasome

1 reference

12 December 2020

Caspase-1 autoproteolysis is differentially required for NLRP1b and NLRP3 inflammasome function.

1 reference

12 December 2020

TH1/TH2 paradigm extended: macrophage polarization as an unappreciated pathogen-driven escape mechanism?

1 reference

12 December 2020

Modified vaccinia virus Ankara-infected dendritic cells present CD4 T-cell epitopes by endogenous major histocompatibility complex class II presentation pathways

1 reference

12 December 2020

Autophagy enhances intestinal epithelial tight junction barrier function by targeting claudin-2 protein degradation

1 reference

12 December 2020

Impaired macrophage autophagy increases the immune response in obese mice by promoting proinflammatory macrophage polarization

1 reference

12 December 2020

mTOR: a pharmacologic target for autophagy regulation

1 reference

12 December 2020

Deficiency of autophagy protein Map1-LC3b mediates IL-17-dependent lung pathology during respiratory viral infection via ER stress-associated IL-1

1 reference

12 December 2020

Autophagy Controls Acquisition of Aging Features in Macrophages

1 reference

12 December 2020

Multiple sclerosis-associated CLEC16A controls HLA class II expression via late endosome biogenesis

1 reference

12 December 2020

The inflammasome: firing up innate immunity

1 reference

12 December 2020

Differential use of autophagy by primary dendritic cells specialized in cross-presentation

1 reference

12 December 2020

Autophagic Degradation of the 26S Proteasome Is Mediated by the Dual ATG8/Ubiquitin Receptor RPN10 in Arabidopsis

1 reference

12 December 2020

Inflammation negatively regulates FOXP3 and regulatory T-cell function via DBC1.

1 reference

12 December 2020

Proteolytic Processing of Interleukin-1 Family Cytokines: Variations on a Common Theme

1 reference

12 December 2020

Therapeutic targeting of autophagy in neurodegenerative and infectious diseases

1 reference

12 December 2020

Chemokine CXCL1-Mediated Neutrophil Trafficking in the Lung: Role of CXCR2 Activation

1 reference

12 December 2020

Innate Immune Defenses Mediated by Two ILC Subsets Are Critical for Protection against Acute Clostridium difficile Infection

1 reference

12 December 2020

MTMR3 risk allele enhances innate receptor-induced signaling and cytokines by decreasing autophagy and increasing caspase-1 activation

1 reference

12 December 2020

Therapy and pharmacological properties of hydroxychloroquine and chloroquine in treatment of systemic lupus erythematosus, rheumatoid arthritis and related diseases

1 reference

12 December 2020

Common γ-chain cytokine signaling is required for macroautophagy induction during CD4 T-cell activation

1 reference

12 December 2020

RUN and FYVE domain-containing protein 4 enhances autophagy and lysosome tethering in response to Interleukin-4.

1 reference

12 December 2020

Pharmaceutical screen identifies novel target processes for activation of autophagy with a broad translational potential.

1 reference

12 December 2020

Human caspase-4 and caspase-5 regulate the one-step non-canonical inflammasome activation in monocytes

1 reference

12 December 2020

Translocation of interleukin-1β into a vesicle intermediate in autophagy-mediated secretion

1 reference

12 December 2020

Autophagy, Metabolism, and Cancer.

1 reference

12 December 2020

Autophagy regulates T lymphocyte proliferation through selective degradation of the cell-cycle inhibitor CDKN1B/p27Kip1.

1 reference

12 December 2020

Lack of autophagy induces steroid-resistant airway inflammation.

1 reference

12 December 2020

The Tumor Antigen NY-ESO-1 Mediates Direct Recognition of Melanoma Cells by CD4 T Cells after Intercellular Antigen Transfer.

1 reference

12 December 2020

Identification of a novel chemokine-dependent molecular mechanism underlying rheumatoid arthritis-associated autoantibody-mediated bone loss

1 reference

12 December 2020

MIF: Implications in the Pathoetiology of Systemic Lupus Erythematosus

1 reference

12 December 2020

Unique role for ATG5 in neutrophil-mediated immunopathology during M. tuberculosis infection

1 reference

12 December 2020

Immunometabolism governs dendritic cell and macrophage function

1 reference

12 December 2020

Signaling through NOD-2 and TLR-4 Bolsters the T cell Priming Capability of Dendritic cells by Inducing Autophagy

1 reference

12 December 2020

Autophagy enforces functional integrity of regulatory T cells by coupling environmental cues and metabolic homeostasis

1 reference

12 December 2020

Macrophage migration inhibitory factor drives neutrophil accumulation by facilitating IL-1β production in a murine model of acute gout

1 reference

12 December 2020

T Cells and Cancer: How Metabolism Shapes Immunity

1 reference

12 December 2020

CD4 T-cell subsets in inflammatory diseases: beyond the Th1/Th2 paradigm

1 reference

12 December 2020

Mystery solved: Trehalose kickstarts autophagy by blocking glucose transport

1 reference

12 December 2020

The autophagy gene Atg16l1 differentially regulates Treg and TH2 cells to control intestinal inflammation.

1 reference

12 December 2020

Autophagy generates citrullinated peptides in human synoviocytes: a possible trigger for anti-citrullinated peptide antibodies.

1 reference

12 December 2020

Elevated Ratio of Th17 Cell-Derived Th1 Cells (CD161( )Th1 Cells) to CD161( )Th17 Cells in Peripheral Blood of Early-Onset Rheumatoid Arthritis Patients

1 reference

12 December 2020

Loss of autophagy enhances MIF/macrophage migration inhibitory factor release by macrophages

1 reference

12 December 2020

Impaired macrophage autophagy induces systemic insulin resistance in obesity

1 reference

12 December 2020

Autophagy proteins in antigen processing for presentation on MHC molecules

1 reference

12 December 2020

Autophagy deficiency in myeloid cells increases susceptibility to obesity-induced diabetes and experimental colitis

1 reference

12 December 2020

Human ULK1 Variation and Susceptibility to Mycobacterium tuberculosis Infection.

1 reference

12 December 2020

Increased autophagy in CD4 T cells of rheumatoid arthritis patients results in T-cell hyperactivation and apoptosis resistance.

1 reference

12 December 2020

Autophagy-dependent regulatory T cells are critical for the control of graft-versus-host disease.

1 reference

12 December 2020

1 reference

12 December 2020

1 reference

12 December 2020

Ustekinumab as Induction and Maintenance Therapy for Crohn’s Disease

1 reference

12 December 2020

Therapeutic Targeting of Autophagy

1 reference

12 December 2020

Antagonism of Interleukin-17A ameliorates experimental hepatic fibrosis by restoring the IL-10/STAT3-suppressed autophagy in hepatocytes.

1 reference

12 December 2020

IBD in 2016: Biologicals and biosimilars in IBD - the road to personalized treatment.

1 reference

12 December 2020

Myeloid ATG16L1 Facilitates Host-Bacteria Interactions in Maintaining Intestinal Homeostasis.

1 reference

12 December 2020

Current and emerging therapeutic targets for IBD.

1 reference

12 December 2020

Human CLEC16A regulates autophagy through modulating mTOR activity

1 reference

12 December 2020

Autophagy and inflammasomes

1 reference

12 December 2020

Autophagy and Autophagy-Related Proteins in CNS Autoimmunity.

1 reference

12 December 2020

Genetic control of autophagy underlies pathogenesis of inflammatory bowel disease

1 reference

12 December 2020

Immunometabolism in early and late stages of rheumatoid arthritis.

1 reference

12 December 2020

Genetic predisposition of IL-10 promoter polymorphisms with risk of multiple sclerosis: A meta-analysis

1 reference

12 December 2020

The protection role of Atg16l1 in CD11c dendritic cells in murine colitis

1 reference

12 December 2020

The MHC locus and genetic susceptibility to autoimmune and infectious diseases

1 reference

12 December 2020

Anti-inflammatory effect of IL-10 mediated by metabolic reprogramming of macrophages.

1 reference

12 December 2020

Inflammatory Bowel Disease: Updates on Molecular Targets for Biologics

1 reference

12 December 2020

Rapamycin regulates macrophage activation by inhibiting NLRP3 inflammasome-p38 MAPK-NFκB pathways in autophagy- and p62-dependent manners

1 reference

12 December 2020

Stimulation of autophagy prevents intestinal mucosal inflammation and ameliorates murine colitis.

1 reference

12 December 2020

Metabolic and Epigenetic Coordination of T Cell and Macrophage Immunity

1 reference

12 December 2020

Pharmacological modulation of autophagy: therapeutic potential and persisting obstacles

1 reference

12 December 2020

Hypoxia inducible factor-1α regulates autophagy via the p27-E2F1 signaling pathway

1 reference

12 December 2020

Metabolic control of type 2 immunity.

1 reference

12 December 2020

The Plasticity of Th17 Cells in the Pathogenesis of Rheumatoid Arthritis

1 reference

12 December 2020

Paneth cells secrete lysozyme via secretory autophagy during bacterial infection of the intestine.

1 reference

12 December 2020

Autophagy dictates metabolism and differentiation of inflammatory immune cells.

1 reference

12 December 2020

Role of interferon regulatory factor-1 in lipopolysaccharide-induced mitochondrial damage and oxidative stress responses in macrophages

1 reference

12 December 2020

Autophagy and mitophagy elements are increased in body fluids of multiple sclerosis-affected individuals

1 reference

12 December 2020

Autophagy-Dependent Generation of Free Fatty Acids Is Critical for Normal Neutrophil Differentiation.

1 reference

12 December 2020

Selective degradation of PU.1 during autophagy represses the differentiation and antitumour activity of TH9 cells

1 reference

12 December 2020

Association between IRGM polymorphisms and tuberculosis risk: A meta-analysis

1 reference

12 December 2020

Autophagy protein ATG16L1 prevents necroptosis in the intestinal epithelium.

1 reference

12 December 2020

Mitophagy and the release of inflammatory cytokines.

1 reference

12 December 2020

Autophagy balances inflammation in innate immunity

1 reference

12 December 2020

The crucial roles of Th17-related cytokines/signal pathways in M. tuberculosis infection

1 reference

12 December 2020

Association of interleukin-10 gene single nucleotide polymorphisms with susceptibility to systemic lupus erythematosus in a Chinese population

1 reference

12 December 2020

Selective autophagy restricts IL-9 secretion from TH9 cells: relevance in cancer growth

1 reference

12 December 2020

ATG-dependent phagocytosis in dendritic cells drives myelin-specific CD4 T cell pathogenicity during CNS inflammation

1 reference

12 December 2020

Dietary trehalose enhances virulence of epidemic Clostridium difficile

1 reference

12 December 2020

Expression level of risk genes of MHC class II is a susceptibility factor for autoimmunity: New insights.

1 reference

12 December 2020

Autophagy and T cell metabolism

1 reference

12 December 2020

Effector T Cells in Multiple Sclerosis

1 reference

12 December 2020

Cargo recognition and degradation by selective autophagy

1 reference

12 December 2020

CD4 T cell autophagy is integral to memory maintenance.

1 reference

12 December 2020

The role of cytokines in T-cell memory in health and disease.

1 reference

12 December 2020

Unraveling the Complex Interplay Between T Cell Metabolism and Function.

1 reference

12 December 2020

Autophagy and MHC-restricted antigen presentation

1 reference

12 December 2020

Cell-Intrinsic Roles for Autophagy in Modulating CD4 T Cell Functions.

1 reference

12 December 2020

Macrophage migration inhibitory factor is required for NLRP3 inflammasome activation.

1 reference

12 December 2020

Effector T Helper Cell Subsets in Inflammatory Bowel Diseases.

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12 December 2020

TNF-α induces autophagy through ERK1/2 pathway to regulate apoptosis in neonatal necrotizing enterocolitis model cells IEC-6

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Identifiers

DOI

10.3389/FIMMU.2018.02914

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30619278 AND SRC:MED&resulttype=core&format=json

17 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30619278 AND SRC:MED&resulttype=core&format=json

17 April 2020

PubMed publication ID

30619278

1 reference