Activation of LncRNA TINCR by H3K27 acetylation promotes Trastuzumab resistance and epithelial-mesenchymal transition by targeting MicroRNA-125b in breast Cancer (Q60917478)

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scientific article published on 08 January 2019

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English	Activation of LncRNA TINCR by H3K27 acetylation promotes Trastuzumab resistance and epithelial-mesenchymal transition by targeting MicroRNA-125b in breast Cancer	scientific article published on 08 January 2019

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scholarly article

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18 April 2020

retracted paper

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Retraction Watch

29 December 2023

https://doi.org/10.1186/s12943-022-01609-6

Activation of LncRNA TINCR by H3K27 acetylation promotes Trastuzumab resistance and epithelial-mesenchymal transition by targeting MicroRNA-125b in breast Cancer (English)

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18 April 2020

molecular medicine

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18 April 2020

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Jianguo Hu

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18 April 2020

Kejian Zou

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18 April 2020

Mulin Ye

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18 April 2020

Yuanwen Chen

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18 April 2020

Chengyi Wu

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18 April 2020

Xin Chen

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18 April 2020

Mingli Han

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18 April 2020

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8 January 2019

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18 April 2020

Molecular Cancer

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18 April 2020

18

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18 April 2020

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18 April 2020

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18 April 2020

Overexpression of ErbB2 in cancer and ErbB2-targeting strategies

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621694

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genes that mediate breast cancer metastasis to lung

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621694

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

American Society of Clinical Oncology/College of American Pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621694

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chromatin modifications and their function

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621694

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro expansion of human breast cancer epithelial and mesenchymal stromal cells: optimization of a coculture model for personalized therapy approaches.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621694

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Trastuzumab as adjuvant therapy for early breast cancer: the importance of accurate human epidermal growth factor receptor 2 testing

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621694

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New response evaluation criteria in solid tumours: revised RECIST guideline (version 1.1)

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621694

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Trastuzumab-induced HER reprogramming in "resistant" breast carcinoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621694

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MiR-125b expression affects the proliferation and apoptosis of human glioma cells by targeting Bmf.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621694

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621694

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CREB binding protein is required for both short-term and long-term memory formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621694

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Asian ethnicity and breast cancer subtypes: a study from the California Cancer Registry

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621694

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lifetime risks of specific breast cancer subtypes among women in four racial/ethnic groups

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621694

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epigenetic factors in cancer development: polycomb group proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621694

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ablation of CBP in forebrain principal neurons causes modest memory and transcriptional defects and a dramatic reduction of histone acetylation but does not affect cell viability

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621694

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

miR-125b is methylated and functions as a tumor suppressor by regulating the ETS1 proto-oncogene in human invasive breast cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621694

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MicroRNA miR-125b induces senescence in human melanoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621694

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Randomized phase II study comparing efficacy and safety of combination-therapy trastuzumab and docetaxel vs. sequential therapy of trastuzumab followed by docetaxel alone at progression as first-line chemotherapy in patients with HER2 metastatic br

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621694

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sirtuin7 oncogenic potential in human hepatocellular carcinoma and its regulation by the tumor suppressors MiR-125a-5p and MiR-125b

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621694

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adding hormonal therapy to chemotherapy and trastuzumab improves prognosis in patients with hormone receptor-positive and human epidermal growth factor receptor 2-positive primary breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621694

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene regulation by the act of long non-coding RNA transcription

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621694

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Remodeling of Ago2-mRNA interactions upon cellular stress reflects miRNA complementarity and correlates with altered translation rates

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621694

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TINCR, staufen1, and cellular differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621694

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

miR-125b targets erythropoietin and its receptor and their expression correlates with metastatic potential and ERBB2/HER2 expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621694

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nuclear lncRNAs as epigenetic regulators-beyond skepticism

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621694

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long non-coding RNAs: new players in cell differentiation and development

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621694

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Central role of Snail1 in the regulation of EMT and resistance in cancer: a target for therapeutic intervention

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621694

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disparities in the risk of the ER/PR/HER2 breast cancer subtypes among Asian Americans in California

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621694

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functions of lncRNA HOTAIR in lung cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621694

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

LncRNA-ATB promotes trastuzumab resistance and invasion-metastasis cascade in breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621694

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MiR-125b Functions as a Tumor Suppressor and Enhances Chemosensitivity to Cisplatin in Osteosarcoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621694

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Downregulation of LncRNA GAS5 causes trastuzumab resistance in breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621694

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Exosome-Transmitted lncARSR Promotes Sunitinib Resistance in Renal Cancer by Acting as a Competing Endogenous RNA.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621694

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A new mechanism of trastuzumab resistance in gastric cancer: MACC1 promotes the Warburg effect via activation of the PI3K/AKT signaling pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621694

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Theophylline controllable RNAi-based genetic switches regulate expression of lncRNA TINCR and malignant phenotypes in bladder cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621694

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

LncPRESS1 Is a p53-Regulated LncRNA that Safeguards Pluripotency by Disrupting SIRT6-Mediated De-acetylation of Histone H3K56.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621694

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The lncRNA CRNDE promotes colorectal cancer cell proliferation and chemoresistance via miR-181a-5p-mediated regulation of Wnt/β-catenin signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621694

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic variation of long non-coding RNA TINCR contribute to the susceptibility and progression of colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621694

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel lncRNA uc.134 represses hepatocellular carcinoma progression by inhibiting CUL4A-mediated ubiquitination of LATS1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621694

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

E2F1 induces TINCR transcriptional activity and accelerates gastric cancer progression via activation of TINCR/STAU1/CDKN2B signaling axis

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621694

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oncogenic long noncoding RNA landscape in breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621694

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The long noncoding RNA, TINCR, functions as a competing endogenous RNA to regulate PDK1 expression by sponging miR-375 in gastric cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621694

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The trophoblast cell surface antigen 2 and miR-125b axis in urothelial bladder cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621694

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TINCR suppresses proliferation and invasion through regulating miR-544a/FBXW7 axis in lung cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621694

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long non-coding RNA UCA1 desensitizes breast cancer cells to trastuzumab by impeding miR-18a repression of Yes-associated protein 1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621694

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TINCR facilitates non-small cell lung cancer progression through BRAF-activated MAPK pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621694

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Up-regulation of ceRNA TINCR by SP1 contributes to tumorigenesis in breast cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621694

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Exosome-mediated transfer of lncRNA‑SNHG14 promotes trastuzumab chemoresistance in breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621694

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long non-coding RNA SNHG14 induces trastuzumab resistance of breast cancer via regulating PABPC1 expression through H3K27 acetylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621694

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SP1-induced lncRNA AGAP2-AS1 expression promotes chemoresistance of breast cancer by epigenetic regulation of MyD88

1 reference

https://pubmed.ncbi.nlm.nih.gov/30621694

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/S12943-018-0931-9

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Europe PubMed Central

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18 April 2020

Dimensions Publication ID

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9 September 2019

https://scigraph.springernature.com/pub.10.1186/s12943-018-0931-9

PMC publication ID

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30621694 AND SRC:MED&resulttype=core&format=json

18 April 2020

PubMed publication ID

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30621694 AND SRC:MED&resulttype=core&format=json

18 April 2020

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