Current status, problems, and perspectives of non-alcoholic fatty liver disease research (Q60910136)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30670907 AND SRC:MED&resulttype=core&format=json

20 April 2020

1 reference

3 August 2022

Current status, problems, and perspectives of non-alcoholic fatty liver disease research (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30670907 AND SRC:MED&resulttype=core&format=json

metabolic dysfunction–associated steatotic liver disease

20 April 2020

main subject

1 reference

8 September 2020

1 reference

7 October 2019

1 reference

8 September 2020

1 reference

8 April 2021

interdisciplinary research

1 reference

PubMed publication ID

6

Eiji Tanaka

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30670907 AND SRC:MED&resulttype=core&format=json

20 April 2020

author name string

Naoki Tanaka

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30670907 AND SRC:MED&resulttype=core&format=json

20 April 2020

Takefumi Kimura

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30670907 AND SRC:MED&resulttype=core&format=json

20 April 2020

Naoyuki Fujimori

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30670907 AND SRC:MED&resulttype=core&format=json

20 April 2020

Tadanobu Nagaya

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30670907 AND SRC:MED&resulttype=core&format=json

20 April 2020

Michiharu Komatsu

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30670907 AND SRC:MED&resulttype=core&format=json

20 April 2020

language of work or name

English

0 references

publication date

1 January 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30670907 AND SRC:MED&resulttype=core&format=json

World Journal of Gastroenterology

20 April 2020

14 January 2019

3 references

8 September 2020

8 April 2021

3 August 2022

9 references

21 March 2019

20 June 2019

22 June 2019

7 October 2019

12 October 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30670907 AND SRC:MED&resulttype=core&format=json

20 April 2020

8 September 2020

8 April 2021

3 August 2022

25

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30670907 AND SRC:MED&resulttype=core&format=json

20 April 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30670907 AND SRC:MED&resulttype=core&format=json

20 April 2020

page(s)

163-177

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30670907 AND SRC:MED&resulttype=core&format=json

Creative Commons Attribution-NonCommercial 4.0 International

20 April 2020

copyright license

8 references

21 March 2019

20 June 2019

22 June 2019

7 October 2019

12 October 2019

8 September 2020

8 April 2021

on focus list of Wikimedia project

3 August 2022

ScienceSource

0 references

cites work

Nonalcoholic steatohepatitis: Mayo Clinic experiences with a hitherto unnamed disease

1 reference

12 December 2020

NAFLD may be a common underlying liver disease in patients with hepatocellular carcinoma in the United States

1 reference

12 December 2020

Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease

1 reference

12 December 2020

Laparoscopic findings in patients with nonalcoholic steatohepatitis

1 reference

12 December 2020

Diagnostic value of biochemical markers (FibroTest-FibroSURE) for the prediction of liver fibrosis in patients with non-alcoholic fatty liver disease

1 reference

12 December 2020

A lean man with nonalcoholic fatty liver disease

1 reference

12 December 2020

Hyaluronic acid levels can predict severe fibrosis and platelet counts can predict cirrhosis in patients with nonalcoholic fatty liver disease

1 reference

12 December 2020

Useful parameters for distinguishing nonalcoholic steatohepatitis with mild steatosis from cryptogenic chronic hepatitis in the Japanese population

1 reference

12 December 2020

The NAFLD fibrosis score: A noninvasive system that identifies liver fibrosis in patients with NAFLD

1 reference

12 December 2020

Noninvasive markers of fibrosis in nonalcoholic fatty liver disease: Validating the European Liver Fibrosis Panel and exploring simple markers

1 reference

12 December 2020

Highly purified eicosapentaenoic acid treatment improves nonalcoholic steatohepatitis

1 reference

12 December 2020

Development and validation of a simple NAFLD clinical scoring system for identifying patients without advanced disease

1 reference

12 December 2020

Hepatic steatosis in leptin-deficient mice is promoted by the PPARgamma target gene Fsp27.

1 reference

12 December 2020

Citrin deficiency as a cause of chronic liver disorder mimicking non-alcoholic fatty liver disease

1 reference

12 December 2020

Partial lipodystrophy and insulin resistant diabetes in a patient with a homozygous nonsense mutation in CIDEC

1 reference

12 December 2020

Nonalcoholic fatty liver disease in Japanese junior high school students: its prevalence and relationship to lifestyle habits

1 reference

12 December 2020

Serum fragmented cytokeratin 18 levels reflect the histologic activity score of nonalcoholic fatty liver disease more accurately than serum alanine aminotransferase levels

1 reference

12 December 2020

Pioglitazone, vitamin E, or placebo for nonalcoholic steatohepatitis

1 reference

12 December 2020

Accurate and simple method for quantification of hepatic fat content using magnetic resonance imaging: a prospective study in biopsy-proven nonalcoholic fatty liver disease

1 reference

12 December 2020

Down-regulation of SREBP-1c is associated with the development of burned-out NASH.

1 reference

12 December 2020

Clinical characteristics of de novo nonalcoholic fatty liver disease following pancreaticoduodenectomy

1 reference

12 December 2020

Characteristics of patients with nonalcoholic steatohepatitis who develop hepatocellular carcinoma.

1 reference

12 December 2020

Human fatty liver disease: old questions and new insights

1 reference

12 December 2020

Platelet count for predicting fibrosis in nonalcoholic fatty liver disease

1 reference

12 December 2020

Validation of the FIB4 index in a Japanese nonalcoholic fatty liver disease population

1 reference

12 December 2020

Disruption of phospholipid and bile acid homeostasis in mice with nonalcoholic steatohepatitis.

1 reference

12 December 2020

Prevalence and associated metabolic factors of nonalcoholic fatty liver disease in the general population from 2009 to 2010 in Japan: a multicenter large retrospective study

1 reference

12 December 2020

Metabolomics identifies an inflammatory cascade involved in dioxin- and diet-induced steatohepatitis.

1 reference

12 December 2020

The liver diseases of lipodystrophy: the long-term effect of leptin treatment

1 reference

12 December 2020

Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome

1 reference

12 December 2020

Body mass index in childhood and adult risk of primary liver cancer

1 reference

12 December 2020

Limitations of liver biopsy and non-invasive diagnostic tests for the diagnosis of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis

1 reference

12 December 2020

Diagnosis and classification of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis: Current concepts and remaining challenges

1 reference

12 December 2020

The pan-caspase inhibitor Emricasan (IDN-6556) decreases liver injury and fibrosis in a murine model of non-alcoholic steatohepatitis

1 reference

12 December 2020

Metabolically healthy obesity, presence or absence of fatty liver, and risk of type 2 diabetes in Japanese individuals: Toranomon Hospital Health Management Center Study 20 (TOPICS 20).

1 reference

12 December 2020

Activated hepatic stellate cells are dependent on self-collagen, cleaved by membrane type 1 matrix metalloproteinase for their growth

1 reference

12 December 2020

Hepatocyte free cholesterol lipotoxicity results from JNK1-mediated mitochondrial injury and is HMGB1 and TLR4-dependent.

1 reference

12 December 2020

Role of white adipose lipolysis in the development of NASH induced by methionine- and choline-deficient diet

1 reference

12 December 2020

Farnesoid X nuclear receptor ligand obeticholic acid for non-cirrhotic, non-alcoholic steatohepatitis (FLINT): a multicentre, randomised, placebo-controlled trial

1 reference

12 December 2020

Adipocyte-specific disruption of fat-specific protein 27 causes hepatosteatosis and insulin resistance in high-fat diet-fed mice.

1 reference

12 December 2020

Intestinal farnesoid X receptor signaling promotes nonalcoholic fatty liver disease.

1 reference

12 December 2020

Steatogenesis in adult-onset type II citrullinemia is associated with down-regulation of PPARα.

1 reference

12 December 2020

Hepatitis B virus (HBV) DNA integration in patients with occult HBV infection and hepatocellular carcinoma.

1 reference

12 December 2020

Pathobiology of liver fibrosis: a translational success story

1 reference

12 December 2020

Role of fibroblast growth factor 21 in the early stage of NASH induced by methionine- and choline-deficient diet

1 reference

12 December 2020

Persistent Organic Pollutants Modify Gut Microbiota-Host Metabolic Homeostasis in Mice Through Aryl Hydrocarbon Receptor Activation.

1 reference

12 December 2020

Evidence-based clinical practice guidelines for nonalcoholic fatty liver disease/nonalcoholic steatohepatitis

1 reference

12 December 2020

Liver Fibrosis, but No Other Histologic Features, Is Associated With Long-term Outcomes of Patients With Nonalcoholic Fatty Liver Disease

1 reference

12 December 2020

Prevalence of fatty liver disease and the economy in China: A systematic review

1 reference

12 December 2020

The Hierarchical Model of NAFLD: Prognostic Significance of Histologic Features in NASH.

1 reference

12 December 2020

Liver fibrosis markers of nonalcoholic steatohepatitis

1 reference

12 December 2020

Development from simple steatosis to liver cirrhosis and hepatocellular carcinoma: a 27-year follow-up case

1 reference

12 December 2020

FibroGENE: A gene-based model for staging liver fibrosis

1 reference

12 December 2020

The severity of nonalcoholic fatty liver disease is associated with gut dysbiosis and shift in the metabolic function of the gut microbiota

1 reference

12 December 2020

Diet, weight loss, and liver health in nonalcoholic fatty liver disease: Pathophysiology, evidence, and practice

1 reference

12 December 2020

Mechanism of the development of nonalcoholic steatohepatitis after pancreaticoduodenectomy

1 reference

12 December 2020

Global epidemiology of nonalcoholic fatty liver disease-Meta-analytic assessment of prevalence, incidence, and outcomes.

1 reference

12 December 2020

The multiple-hit pathogenesis of non-alcoholic fatty liver disease (NAFLD).

1 reference

12 December 2020

Development and validation of a noninvasive prediction model for nonalcoholic steatohepatitis resolution after lifestyle intervention.

1 reference

12 December 2020

Elafibranor, an Agonist of the Peroxisome Proliferator-Activated Receptor-α and -δ, Induces Resolution of Nonalcoholic Steatohepatitis Without Fibrosis Worsening

1 reference

12 December 2020

Controlled attenuation parameter is correlated with actual hepatic fat content in patients with non-alcoholic fatty liver disease with none-to-mild obesity and liver fibrosis.

1 reference

12 December 2020

Clinicopathological characteristics of non-B non-C hepatocellular carcinoma without past hepatitis B virus infection

1 reference

12 December 2020

Long-Term Pioglitazone Treatment for Patients With Nonalcoholic Steatohepatitis and Prediabetes or Type 2 Diabetes Mellitus: A Randomized Trial.

1 reference

12 December 2020

Hepatocellular carcinoma in patients with non-alcoholic fatty liver disease

1 reference

12 December 2020

Randomised clinical study: GR-MD-02, a galectin-3 inhibitor, vs. placebo in patients having non-alcoholic steatohepatitis with advanced fibrosis

1 reference

12 December 2020

Pathological findings of nonalcoholic steatohepatitis and nonalcoholic fatty liver disease.

1 reference

12 December 2020

Association between endotoxemia and histological features of nonalcoholic fatty liver disease

1 reference

12 December 2020

Targeting CASP8 and FADD-like apoptosis regulator ameliorates nonalcoholic steatohepatitis in mice and nonhuman primates.

1 reference

12 December 2020

NASH: Novel therapeutic strategies targeting ASK1 in NASH.

1 reference

12 December 2020

Treatment of NAFLD with diet, physical activity and exercise.

1 reference

12 December 2020

Targeting nuclear receptors for the treatment of fatty liver disease

1 reference

12 December 2020

AST to Platelet Ratio Index and fibrosis 4 calculator scores for non-invasive assessment of hepatic fibrosis in patients with non-alcoholic fatty liver disease.

1 reference

12 December 2020

A simple scoring system using type IV collagen 7S and aspartate aminotransferase for diagnosing nonalcoholic steatohepatitis and related fibrosis.

1 reference

12 December 2020

The role of thiazolidinediones in hepatocellular carcinoma risk reduction: a population-based cohort study in Taiwan

1 reference

12 December 2020

Wolman's disease and cholesteryl ester storage disorder: the phenotypic spectrum of lysosomal acid lipase deficiency

1 reference

12 December 2020

A Randomized, Placebo-Controlled Trial of Cenicriviroc for Treatment of Nonalcoholic Steatohepatitis with Fibrosis.

1 reference

12 December 2020

Growth arrest and DNA damage-inducible 45α protects against nonalcoholic steatohepatitis induced by methionine- and choline-deficient diet

1 reference

12 December 2020

Should we undertake surveillance for HCC in patients with NAFLD?

1 reference

12 December 2020

Current and future pharmacological therapies for NAFLD/NASH.

1 reference

12 December 2020

Serum Wisteria floribunda agglutinin-positive Mac-2 binding protein more reliably distinguishes liver fibrosis stages in non-alcoholic fatty liver disease than serum Mac-2 binding protein

1 reference

12 December 2020

Clinical epidemiology and disease burden of nonalcoholic fatty liver disease

1 reference

12 December 2020

Nonalcoholic fatty liver disease is associated with dysbiosis independent of body mass index and insulin resistance.

1 reference

12 December 2020

Effects of a sodium-glucose cotransporter 2 inhibitor in nonalcoholic fatty liver disease complicated by diabetes mellitus: Preliminary prospective study based on serial liver biopsies.

1 reference

12 December 2020

Nonalcoholic fatty liver disease and the ongoing role of liver biopsy evaluation.

1 reference

12 December 2020

Use of Mac-2 binding protein as a biomarker for nonalcoholic fatty liver disease diagnosis.

1 reference

12 December 2020

Natural history of nonalcoholic fatty liver disease: A prospective follow-up study with serial biopsies.

1 reference

12 December 2020

Serum autotaxin levels are correlated with hepatic fibrosis and ballooning in patients with non-alcoholic fatty liver disease.

1 reference

12 December 2020

To die or not to die: death signaling in nonalcoholic fatty liver disease.

1 reference

12 December 2020

Mild drinking habit is a risk factor for hepatocarcinogenesis in non-alcoholic fatty liver disease with advanced fibrosis.

1 reference

12 December 2020

Wisteria floribunda agglutinin-positive Mac-2-binding protein and type 4 collagen 7S: useful markers for the diagnosis of significant fibrosis in patients with non-alcoholic fatty liver disease

1 reference

12 December 2020

Liver fat imaging-a clinical overview of ultrasound, CT, and MR imaging

1 reference

12 December 2020

The gut-liver axis and the intersection with the microbiome

1 reference

12 December 2020

Modeling NAFLD Disease Burden in China, France, Germany, Italy, Japan, Spain, United Kingdom, and United States for the period 2016-2030

1 reference

12 December 2020

Magnetic Resonance vs Transient Elastography Analysis of Patients With Nonalcoholic Fatty Liver Disease: A Systematic Review and Pooled Analysis of Individual Participants

1 reference

12 December 2020

Miglitol attenuates non-alcoholic steatohepatitis in diabetic patients

1 reference

12 December 2020

Management of nonalcoholic fatty liver disease: Lessons learned from type 2 diabetes

1 reference

12 December 2020

Effect of luseogliflozin on hepatic fat content in type 2 diabetes patients with non-alcoholic fatty liver disease: A prospective, single-arm trial (LEAD trial)

1 reference

12 December 2020

Effect of pioglitazone on bone mineral density in patients with nonalcoholic steatohepatitis: A 36-month clinical trial

1 reference

12 December 2020

Histologic improvement of NAFLD in patients with obesity after bariatric surgery based on standardized NAS (NAFLD activity score)

1 reference

12 December 2020

Small metabolites, possible big changes: a microbiota-centered view of non-alcoholic fatty liver disease

1 reference

12 December 2020

Global Perspectives on Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis

1 reference

12 December 2020

Current status of imaging in nonalcoholic fatty liver disease

1 reference

12 December 2020

Factors Associated With Histologic Response in Adult Patients With Nonalcoholic Steatohepatitis

1 reference

12 December 2020

Pegbelfermin (BMS-986036), a PEGylated fibroblast growth factor 21 analogue, in patients with non-alcoholic steatohepatitis: a randomised, double-blind, placebo-controlled, phase 2a trial

1 reference

12 December 2020

Fecal SCFAs and SCFA-producing bacteria in gut microbiome of human NAFLD as a putative link to systemic T-cell activation and advanced disease

1 reference

12 December 2020

Identifiers

DOI

10.3748/WJG.V25.I2.163

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30670907 AND SRC:MED&resulttype=core&format=json

20 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30670907 AND SRC:MED&resulttype=core&format=json

20 April 2020

PubMed publication ID

30670907

1 reference