Neurological and Inflammatory Manifestations in Sjögren's Syndrome: The Role of the Kynurenine Metabolic Pathway (Q60907801)

5

object named as

Thiago Mattar Cunha

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author name string

Fabíola Reis de Oliveira

1

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Marina Zilio Fantucci

2

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Leidiane Adriano

3

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Valéria Valim

4

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Paulo Louzada-Junior

International Journal of Molecular Sciences

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language of work or name

English

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publication date

8 December 2018

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25 April 2019

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30 June 2019

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3 October 2019

19 November 2019

24 September 2020

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25 April 2019

17 June 2019

30 June 2019

12 September 2019

3 October 2019

19 November 2019

24 September 2020

19

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issue

12

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page(s)

3953

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copyright license

Creative Commons Attribution

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25 April 2019

17 June 2019

30 June 2019

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19 November 2019

24 September 2020

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on focus list of Wikimedia project

ScienceSource

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cites work

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Muscarinic acetylcholine receptor antibodies as a new marker of dry eye Sjögren syndrome.

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Kynurenine 3-mono-oxygenase activity and neurotoxic kynurenine metabolites increase in the spinal cord of rats with experimental allergic encephalomyelitis

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Involvement of the peripheral nervous system in primary Sjögren's syndrome

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Are women with Sjögren's syndrome androgen-deficient?

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Diclofenac increases the accumulation of kynurenate following tryptophan pretreatment in the rat: a possible factor contributing to its antihyperalgesic effect

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Estrogen and inflammation increase the excitability of rat temporomandibular joint afferent neurons

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Aspirin down-regulates tryptophan degradation in stimulated human peripheral blood mononuclear cells in vitro

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Diffusion-weighted MR microimaging of the lacrimal glands in patients with Sjogren's syndrome

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Indolamine 2,3-dioxygenase is expressed in the CNS and down-regulates autoimmune inflammation

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Autonomic brainstem nuclei are linked to the hippocampus

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Neurotrophic keratopathy and diabetes mellitus

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Loss of parasympathetic innervation leads to sustained expression of pro-inflammatory genes in the rat lacrimal gland

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Alterations in corneal sensitivity and nerve morphology in patients with primary Sjögren's syndrome

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Central nervous system abnormalities in fibromyalgia and chronic fatigue syndrome: new concepts in treatment

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Serotonin as a modulator of glutamate- and GABA-mediated neurotransmission: implications in physiological functions and in pathology

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Neuroendocrine dysfunction in Sjogren's syndrome

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Season, sex, age, and education as modifiers of the effects of outdoor air pollution on daily mortality in Shanghai, China: The Public Health and Air Pollution in Asia (PAPA) Study

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[Correlation between signals and symptoms of dry eye in Sjögren's syndrome patients]

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Neural regulation of lacrimal gland secretory processes: relevance in dry eye diseases

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Kynurenic acid triggers firm arrest of leukocytes to vascular endothelium under flow conditions.

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Brain indoleamine 2,3-dioxygenase contributes to the comorbidity of pain and depression

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BLyS upregulation in Sjogren's syndrome associated with lymphoproliferative disorders, higher ESSDAI score and B-cell clonal expansion in the salivary glands.

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Classification and characterisation of peripheral neuropathies in 102 patients with primary Sjögren's syndrome.

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16/6-idiotype expressing antibodies induce brain inflammation and cognitive impairment in mice: the mosaic of central nervous system involvement in lupus

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Tryptophan metabolism and immunogenetics in major depression: a role for interferon-γ gene

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Peripheral regulatory cells immunophenotyping in primary Sjögren's syndrome: a cross-sectional study.

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Paradox effects of kynurenines on LTP induction in the Wistar rat. An in vivo study.

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Network beyond IDO in psychiatric disorders: revisiting neurodegeneration hypothesis

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Modular transcriptional repertoire analyses of adults with systemic lupus erythematosus reveal distinct type I and type II interferon signatures

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Central nervous system involvement in primary Sjogren`s syndrome manifesting as multiple sclerosis

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The contribution of epigenetics in Sjögren's Syndrome

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Use of a novel high-resolution magnetic resonance neurography protocol to detect abnormal dorsal root Ganglia in Sjögren patients with neuropathic pain: case series of 10 patients and review of the literature

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Comparison of diagnostic tests in distinct well-defined conditions related to dry eye disease

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Psychiatric manifestations of primary Sjögren's syndrome: a case report and literature review

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Vagus nerve controls resolution and pro-resolving mediators of inflammation

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Loss of cerebral white matter in primary Sjögren's syndrome: a controlled volumetric magnetic resonance imaging study

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Glutamate receptor antibodies in neurological diseases: anti-AMPA-GluR3 antibodies, anti-NMDA-NR1 antibodies, anti-NMDA-NR2A/B antibodies, anti-mGluR1 antibodies or anti-mGluR5 antibodies are present in subpopulations of patients with either: epilep

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Sjögren syndrome and neuromyelitis optica spectrum disorder co-exist in a common autoimmune milieu

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Association of hippocampal atrophy with cerebrospinal fluid antibodies against the NR2 subtype of the N-methyl-D-aspartate receptor in patients with systemic lupus erythematosus and patients with primary Sjögren's syndrome

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Umbilical cord mesenchymal stem cells inhibit the differentiation of circulating T follicular helper cells in patients with primary Sjögren's syndrome through the secretion of indoleamine 2,3-dioxygenase

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Ocular and systemic morbidity in a longitudinal cohort of Sjögren's syndrome

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Skeletal muscle PGC-1α1 modulates kynurenine metabolism and mediates resilience to stress-induced depression

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IDO2 in Immunomodulation and Autoimmune Disease

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Predominant Glandular Cholinergic Dysautonomia in Patients With Primary Sjögren's Syndrome

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The hippocampus and TNF: Common links between chronic pain and depression

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Ocular neuropathic pain

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Clinical Characteristics and Outcome of Primary Sjogren's Syndrome: A Large Asian Indian Cohort

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The Clinical Characteristics of Primary Sjogren's Syndrome With Neuromyelitis Optica Spectrum Disorder in China: A STROBE-Compliant Article

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Type I and II interferon signatures in Sjogren's syndrome pathogenesis: Contributions in distinct clinical phenotypes and Sjogren's related lymphomagenesis

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Characterization of systemic disease in primary Sjögren's syndrome: EULAR-SS Task Force recommendations for articular, cutaneous, pulmonary and renal involvements

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Fatigue in Primary Sjögren's Syndrome: Clinical, Laboratory, Psychometric, and Biologic Associations

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Screening of the Seed Region of MIR184 in Keratoconus Patients from Saudi Arabia.

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Pharmacological kynurenine 3-monooxygenase enzyme inhibition significantly reduces neuropathic pain in a rat model

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Early diagnosis of primary Sjögren's syndrome: EULAR-SS task force clinical recommendations

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A Transcriptional Signature of Fatigue Derived from Patients with Primary Sjögren's Syndrome

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Sicca symptoms are associated with similar fatigue, anxiety, depression, and quality-of-life impairments in patients with and without primary Sjögren's syndrome

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Fibromyalgia and Bipolar Disorder: Emerging Epidemiological Associations and Shared Pathophysiology.

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Computational meta-analysis of statistical parametric maps in major depression

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Association of Increased Treg Cell Levels With Elevated Indoleamine 2,3-Dioxygenase Activity and an Imbalanced Kynurenine Pathway in Interferon-Positive Primary Sjögren's Syndrome

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Autonomic dysfunction in primary Sjogren's syndrome: a prospective cohort analysis of 154 Korean patients

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Inflammation Models of Depression in Rodents: Relevance to Psychotropic Drug Discovery

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Silencing spinal interneurons inhibits immune suppressive autonomic reflexes caused by spinal cord injury

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Pain, xerostomia, and younger age are major determinants of fatigue in Korean patients with primary Sjögren's syndrome: a cohort study

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12 December 2020

Kynurenine metabolic balance is disrupted in the hippocampus following peripheral lipopolysaccharide challenge

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12 December 2020

Hepatitis Delta Virus Detected in Salivary Glands of Sjögren's Syndrome Patients and Recapitulates a Sjögren's Syndrome-Like Phenotype in Vivo

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Kynurenine pathway metabolism and the microbiota-gut-brain axis

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Metabolic Profiling of Systemic Lupus Erythematosus and Comparison with Primary Sjögren's Syndrome and Systemic Sclerosis

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Primary Sjögren's syndrome is associated with significant cognitive dysfunction.

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The kynurenine pathway and the brain: Challenges, controversies and promises

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Ionotropic glutamate receptors contribute to pain transmission and chronic pain

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The role of B7 family costimulatory molecules and indoleamine 2,3-dioxygenase in primary Sjögren's syndrome and systemic sclerosis.

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Cognition, depression, fatigue, and quality of life in primary Sjögren's syndrome: correlations

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First-in-Human Phase I Study of the Oral Inhibitor of Indoleamine 2,3-Dioxygenase-1 Epacadostat (INCB024360) in Patients with Advanced Solid Malignancies.

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Neural regulation of immunity: molecular mechanisms and clinical translation.

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Associations between endogenous sex hormones and MRI structural changes in patients with symptomatic knee osteoarthritis

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Reviewing primary Sjögren's syndrome: beyond the dryness - From pathophysiology to diagnosis and treatment

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Impact of pain on cognitive functions in primary Sjögren syndrome with small fiber neuropathy: 10 cases and a literature review

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Development of new extra-glandular manifestations or associated auto-immune diseases after establishing the diagnosis of primary Sjögren's syndrome : A long-term study of the Antonius Nieuwegein Sjögren (ANS) cohort

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Characterization of the Effects of L-4-Chlorokynurenine on Nociception in Rodents

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12 December 2020

Is extra-glandular organ damage in primary Sjögren's syndrome related to the presence of systemic auto-antibodies and/or hypergammaglobulinemia? A long-term cohort study with 110 patients from the Netherlands.

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12 December 2020

Goblet Cells Contribute to Ocular Surface Immune Tolerance-Implications for Dry Eye Disease.

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MicroRNAs in ocular surface and dry eye diseases: Good, bad and healing situations

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Estradiol upregulates voltage-gated sodium channel 1.7 in trigeminal ganglion contributing to hyperalgesia of inflamed TMJ.

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12 December 2020

Identification of a Sjögren's syndrome susceptibility locus at OAS1 that influences isoform switching, protein expression, and responsiveness to type I interferons

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12 December 2020

Inhibition of the kynurenine pathway protects against reactive microglial-associated reductions in the complexity of primary cortical neurons

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12 December 2020

Upregulation of neuronal kynurenine 3-monooxygenase mediates depression-like behavior in a mouse model of neuropathic pain.

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TFOS DEWS II Sex, Gender, and Hormones Report.

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Serotonin hormonally regulates lacrimal gland secretory function via the serotonin type 3a receptor

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Association of Trauma and Posttraumatic Stress Disorder With Incident Systemic Lupus Erythematosus in a Longitudinal Cohort of Women

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An overview of pathways encoding nociception

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Estradiol Sensitizes the Transient Receptor Potential Vanilloid 1 Receptor in Pain Responses

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Estrogen Modulates Corneal Nociception and Maintains Corneal Homeostasis in Rat Eye.

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Glia- and tissue-specific changes in the Kynurenine Pathway after treatment of mice with lipopolysaccharide and dexamethasone

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Cardiac ischemia/reperfusion injury is inversely affected by thyroid hormones excess or deficiency in male Wistar rats

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The Effect of Low-Dose Aspirin on Dry Eye Parameters and Ocular Surface Disease Index Questionnaire

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Glial and tissue-specific regulation of Kynurenine Pathway dioxygenases by acute stress of mice.

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The tolerogenic peptide hCDR1 immunomodulates cytokine and regulatory molecule gene expression in blood mononuclear cells of primary Sjogren's syndrome patients

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Kynurenine pathway is altered in patients with SLE and associated with severe fatigue.

1 reference

12 December 2020

Bisphenol-A alters microbiota metabolites derived from aromatic amino acids and worsens disease activity during colitis

1 reference

12 December 2020

An update on the role of type I interferons in systemic lupus erythematosus and Sjögrenʼs syndrome

1 reference

12 December 2020

Detection of atrophy of dorsal root ganglion with 3-T magnetic resonance neurography in sensory ataxic neuropathy associated with Sjögren's syndrome

1 reference

12 December 2020

Role of Kynurenine pathway and its metabolites in mood disorders: A systematic review and meta-analysis of clinical studies

1 reference

12 December 2020

Relationship of MR imaging of submandibular glands to hyposalivation in Sjögren's syndrome

1 reference

12 December 2020