Ultrapotent effects of salvinorin A, a hallucinogenic compound from Salvia divinorum, on LPS-stimulated murine macrophages and its anti-inflammatory action in vivo (Q60686096)

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scientific article published on 16 April 2011

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English	Ultrapotent effects of salvinorin A, a hallucinogenic compound from Salvia divinorum, on LPS-stimulated murine macrophages and its anti-inflammatory action in vivo	scientific article published on 16 April 2011

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scholarly article

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28 January 2020

Ultrapotent effects of salvinorin A, a hallucinogenic compound from Salvia divinorum, on LPS-stimulated murine macrophages and its anti-inflammatory action in vivo (English)

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28 January 2020

Salvia divinorum

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4

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28 January 2020

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28 January 2020

Jordan Zjawiony

8

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28 January 2020

10

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28 January 2020

Raffaele Capasso

11

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28 January 2020

author name string

Gabriella Aviello

1

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28 January 2020

Francesca Borrelli

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28 January 2020

Francesca Guida

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28 January 2020

Kevin Lewellyn

5

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28 January 2020

Maria De Chiaro

6

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28 January 2020

Sabatino Maione

9

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28 January 2020

publication date

16 April 2011

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28 January 2020

Journal of Molecular Medicine

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28 January 2020

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28 January 2020

9

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28 January 2020

891-902

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28 January 2020

Carrageenan-induced paw edema in the rat and mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/21499737

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Central nervous system plasticity in the tonic pain response to subcutaneous formalin injection

1 reference

https://pubmed.ncbi.nlm.nih.gov/21499737

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Studies toward the pharmacophore of salvinorin A, a potent kappa opioid receptor agonist

1 reference

https://pubmed.ncbi.nlm.nih.gov/21499737

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antinociceptive profile of salvinorin A, a structurally unique kappa opioid receptor agonist

1 reference

https://pubmed.ncbi.nlm.nih.gov/21499737

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of the plant-derived kappa-opioid hallucinogen salvinorin A in nonhuman primates

1 reference

https://pubmed.ncbi.nlm.nih.gov/21499737

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular and molecular mechanisms involved in the neurotoxicity of opioid and psychostimulant drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/21499737

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Exposure to the selective kappa-opioid receptor agonist salvinorin A modulates the behavioral and molecular effects of cocaine in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/21499737

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Salvinorin A: from natural product to human therapeutics

1 reference

https://pubmed.ncbi.nlm.nih.gov/21499737

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of morphine, pentobarbital and amphetamine on formalin-induced behaviours in infant rats: sedation versus specific suppression of pain

1 reference

https://pubmed.ncbi.nlm.nih.gov/21499737

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacological evaluation of the natural constituent of Cannabis sativa, cannabichromene and its modulation by Δ(9)-tetrahydrocannabinol

1 reference

https://pubmed.ncbi.nlm.nih.gov/21499737

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nitric oxide and cell viability in inflammatory cells: a role for NO in macrophage function and fate.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21499737

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Salvinorin A: allosteric interactions at the mu-opioid receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/21499737

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cannabinoid CB2 receptors: a therapeutic target for the treatment of inflammatory and neuropathic pain

1 reference

https://pubmed.ncbi.nlm.nih.gov/21499737

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-10 and the interleukin-10 receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/21499737

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Salvia divinorum and the unique diterpene hallucinogen, Salvinorin (divinorin) A.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21499737

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The hallucinogenic herb Salvia divinorum and its active ingredient salvinorin A reduce inflammation-induced hypermotility in mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21499737

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Emerging strategies for exploiting cannabinoid receptor agonists as medicines

1 reference

https://pubmed.ncbi.nlm.nih.gov/21499737

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nitric oxide and macrophage function

1 reference

https://pubmed.ncbi.nlm.nih.gov/21499737

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nitric oxide and peroxynitrite in health and disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/21499737

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kappa opioid mediation of cannabinoid effects of the potent hallucinogen, salvinorin A, in rodents

1 reference

https://pubmed.ncbi.nlm.nih.gov/21499737

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of mu-, delta-, and kappa-opioid receptor-like immunoreactivities in rat dorsal root ganglia after carrageenan-induced inflammation

1 reference

https://pubmed.ncbi.nlm.nih.gov/21499737

12 December 2020

based on heuristic

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Salvinorin A exerts opposite presynaptic controls on neurotransmitter exocytosis from mouse brain nerve terminals

1 reference

https://pubmed.ncbi.nlm.nih.gov/21499737

12 December 2020

based on heuristic

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Involvement of kappa-opioid and endocannabinoid system on Salvinorin A-induced reward

1 reference

https://pubmed.ncbi.nlm.nih.gov/21499737

12 December 2020

based on heuristic

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Salvinorin A: the "magic mint" hallucinogen finds a molecular target in the kappa opioid receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/21499737

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Innate immunity and inflammation: a transcriptional paradigm

1 reference

https://pubmed.ncbi.nlm.nih.gov/21499737

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeting the endocannabinoid system: to enhance or reduce?

1 reference

https://pubmed.ncbi.nlm.nih.gov/21499737

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The hallucinogenic herb Salvia divinorum and its active ingredient salvinorin A inhibit enteric cholinergic transmission in the guinea-pig ileum

1 reference

https://pubmed.ncbi.nlm.nih.gov/21499737

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cannabinoid CB1 receptor elevation of intracellular calcium in neuroblastoma SH-SY5Y cells: interactions with muscarinic and delta-opioid receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/21499737

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Salvinorin A inhibits colonic transit and neurogenic ion transport in mice by activating kappa-opioid and cannabinoid receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/21499737

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-1beta-mediated induction of Cox-2 in the CNS contributes to inflammatory pain hypersensitivity

1 reference

https://pubmed.ncbi.nlm.nih.gov/21499737

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fas ligation on macrophages enhances IL-1R1-Toll-like receptor 4 signaling and promotes chronic inflammation

1 reference

https://pubmed.ncbi.nlm.nih.gov/21499737

12 December 2020

based on heuristic

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Caffeic acid derivatives: in vitro and in vivo anti-inflammatory properties.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21499737

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potential anxiolytic- and antidepressant-like effects of salvinorin A, the main active ingredient of Salvia divinorum, in rodents

1 reference

https://pubmed.ncbi.nlm.nih.gov/21499737

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclooxygenase-2 is up-regulated by interleukin-1 beta in human colorectal cancer cells via multiple signaling pathways.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21499737

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biosynthesis and inactivation of the endocannabinoid 2-arachidonoylglycerol in circulating and tumoral macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/21499737

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alternatively activated macrophages in infection and autoimmunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/21499737

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of kappa-opioid receptors in the effects of salvinorin A and ketamine on attention in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/21499737

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cannabidiol, a safe and non-psychotropic ingredient of the marijuana plant Cannabis sativa, is protective in a murine model of colitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21499737

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of two active compounds obtained from the essential oil of Cordia verbenacea on the acute inflammatory responses elicited by LPS in the rat paw.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21499737

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hallucinatory and rewarding effect of salvinorin A in zebrafish: kappa-opioid and CB1-cannabinoid receptor involvement

1 reference

https://pubmed.ncbi.nlm.nih.gov/21499737

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lipopolysaccharide-induced transcriptional activation of interleukin-10 is mediated by MAPK- and NF-kappaB-induced CCAAT/enhancer-binding protein delta in mouse macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/21499737

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a selective nonpeptide antagonist of the anaphylatoxin C3a receptor that demonstrates antiinflammatory activity in animal models

1 reference

https://pubmed.ncbi.nlm.nih.gov/21499737

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Up-regulation of prostaglandin biosynthesis by leukotriene C4 in elicited mice peritoneal macrophages activated with lipopolysaccharide/interferon-{gamma}.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21499737

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibitory effect of salvinorin A, from Salvia divinorum, on ileitis-induced hypermotility: cross-talk between kappa-opioid and cannabinoid CB(1) receptors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21499737

12 December 2020

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inferred from PubMed ID database lookup

Identifiers

10.1007/S00109-011-0752-4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21499737 AND SRC:MED&resulttype=core&format=json

28 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21499737 AND SRC:MED&resulttype=core&format=json

28 January 2020

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