DNA binding and 3′–5′ exonuclease activity in the murine alternatively-spliced p53 protein (Q60357497)

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11 November 2019

title

DNA binding and 3'-5' exonuclease activity in the murine alternatively-spliced p53 protein (English)

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11 November 2019

7

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11 November 2019

6

Varda Rotter

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11 November 2019

Roland Wolkowicz

5

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author name string

Zippora Shakked

1

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11 November 2019

Michael Yavnilovitch

2

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11 November 2019

Naama Kessler

4

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11 November 2019

A Joseph Kalb Gilboa

3

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11 November 2019

language of work or name

English

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publication date

1 August 2002

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11 November 2019

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11 November 2019

volume

21

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11 November 2019

issue

33

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11 November 2019

page(s)

5117-5126

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The C-terminus of p53: the more you learn the less you know

11 November 2019

cites work

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Maintenance of genomic integrity by p53: complementary roles for activated and non-activated p53.

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p53-dependent apoptosis is regulated by a C-terminally alternatively spliced form of murine p53

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Involvement of p53 in cell differentiation and development

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Reciprocal interference between the sequence-specific core and nonspecific C-terminal DNA binding domains of p53: implications for regulation

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7 January 2021

Immunologically distinct p53 molecules generated by alternative splicing

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Latent and active p53 are identical in conformation

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7 January 2021

Exonucleolytic proofreading by p53 protein

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7 January 2021

The carboxyl-terminal domain of the p53 protein regulates sequence-specific DNA binding through its nonspecific nucleic acid-binding activity

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7 January 2021

Structural principles for the inhibition of the 3'-5' exonuclease activity of Escherichia coli DNA polymerase I by phosphorothioates

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7 January 2021

Nucleoside phosphorothioates

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Definition of a consensus binding site for p53

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Transcriptional regulation by p53 through intrinsic DNA/chromatin binding and site-directed cofactor recruitment.

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7 January 2021

A transcriptionally active DNA-binding site for human p53 protein complexes

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7 January 2021

The complexity of p53 modulation: emerging patterns from divergent signals

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7 January 2021

Database of p53 gene somatic mutations in human tumors and cell lines: updated compilation and future prospects

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7 January 2021

Conformational shifts propagate from the oligomerization domain of p53 to its tetrameric DNA binding domain and restore DNA binding to select p53 mutants.

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7 January 2021

Alternatively spliced p53 RNA in transformed and normal cells of different tissue types

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7 January 2021

Excision of mismatched nucleotides from DNA: a potential mechanism for enhancing DNA replication fidelity by the wild-type p53 protein

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7 January 2021

Allosteric activation of latent p53 tetramers

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7 January 2021

Different regulation of the p53 core domain activities 3'-to-5' exonuclease and sequence-specific DNA binding

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7 January 2021

Covalent and noncovalent modifiers of the p53 protein

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7 January 2021

p53: puzzle and paradigm

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7 January 2021

Surface plasmon resonance measurements reveal stable complex formation between p53 and DNA polymerase alpha

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7 January 2021

Endogenous p53 protein generated from wild-type alternatively spliced p53 RNA in mouse epidermal cells

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7 January 2021

p53, the cellular gatekeeper for growth and division

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7 January 2021

Twenty years of p53 research: structural and functional aspects of the p53 protein

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7 January 2021

p53 Protein exhibits 3'-to-5' exonuclease activity

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7 January 2021

Protein-DNA binding correlates with structural thermostability for the full-length human p53 protein.

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7 January 2021

Structural and functional involvement of p53 in BER in vitro and in vivo

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7 January 2021

Direct involvement of p53 in the base excision repair pathway of the DNA repair machinery

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7 January 2021

Regulation of the p53 tumor suppressor protein

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7 January 2021

Regulation and function of the p53 tumor suppressor protein

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7 January 2021

p53-dependent cell cycle control: response to genotoxic stress

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7 January 2021

A DNA binding domain is contained in the C-terminus of wild type p53 protein

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7 January 2021

Substrate specificity of the p53-associated 3'-5' exonuclease

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7 January 2021

Role of heteroduplex joints in the functional interactions between human Rad51 and wild-type p53.

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7 January 2021

p53 tumor-suppressor gene: clues to molecular carcinogenesis

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7 January 2021

Isolation of a full-length mouse cDNA clone coding for an immunologically distinct p53 molecule

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7 January 2021

Augmented DNA-binding activity of p53 protein encoded by a carboxyl-terminal alternatively spliced mRNA is blocked by p53 protein encoded by the regularly spliced form

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7 January 2021

Alternatively spliced forms in the carboxy-terminal domain of the p53 protein regulate its ability to promote annealing of complementary single strands of nucleic acids

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7 January 2021

Wild-type alternatively spliced p53: binding to DNA and interaction with the major p53 protein in vitro and in cells.

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7 January 2021

Sequence-specific DNA binding by p53: identification of target sites and lack of binding to p53 - MDM2 complexes

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7 January 2021

A role for p53 in base excision repair.

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1205667

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12140762 AND SRC:MED&resulttype=core&format=json

11 November 2019

1 reference