Ginsenoside Rg1 Prevents Doxorubicin-Induced Cardiotoxicity through the Inhibition of Autophagy and Endoplasmic Reticulum Stress in Mice (Q59792845)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30463294 AND SRC:MED&resulttype=core&format=json

5 May 2020

main subject

molecular biology

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endoplasmic reticulum

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1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30463294 AND SRC:MED&resulttype=core&format=json

5 May 2020

author name string

Cheng-Bin Li

2

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5 May 2020

Qing-Ling Liu

3

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5 May 2020

Ping Li

4

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5 May 2020

Hua Yang

5

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30463294 AND SRC:MED&resulttype=core&format=json

5 May 2020

Zhi-Meng Xu

full work available at URL

1

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language of work or name

English

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publication date

20 November 2018

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November 2018

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https://www.mdpi.com/1422-0067/19/11/3658

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published in

International Journal of Molecular Sciences

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5 May 2020

volume

19

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5 May 2020

issue

11

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Creative Commons Attribution 4.0 International

5 May 2020

page(s)

3658

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copyright license

start time

20 November 2018

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

PeptideYY and insulin coexist in beta-granules in B cells of the Madagascan lizard, Zonosaurus laticaudatus

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12 December 2020

Der3p/Hrd1p Is Required for Endoplasmic Reticulum-associated Degradation of Misfolded Lumenal and Integral Membrane Proteins

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Autophagy is activated for cell survival after endoplasmic reticulum stress

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ER-phagy: selective autophagy of the endoplasmic reticulum.

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Coordination of growth and endoplasmic reticulum stress signaling by regulator of calcineurin 1 (RCAN1), a novel ATF6-inducible gene

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Transcription factor GATA4 inhibits doxorubicin-induced autophagy and cardiomyocyte death

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Regulation of AKT phosphorylation at Ser473 and Thr308 by endoplasmic reticulum stress modulates substrate specificity in a severity dependent manner

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The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation

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Road to Ruin: Targeting Proteins for Degradation in the Endoplasmic Reticulum

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12 December 2020

Ginsenoside Rg1 inhibits autophagy in H9c2 cardiomyocytes exposed to hypoxia/reoxygenation

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12 December 2020

Doxorubicin-induced cardiomyopathy: from molecular mechanisms to therapeutic strategies

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12 December 2020

The impact of the unfolded protein response on human disease

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12 December 2020

Doxorubicin-induced cardiotoxicity: from bioenergetic failure and cell death to cardiomyopathy.

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12 December 2020

The ginsenoside Rg1 prevents transverse aortic constriction-induced left ventricular hypertrophy and cardiac dysfunction by inhibiting fibrosis and enhancing angiogenesis

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IRE1: ER stress sensor and cell fate executor

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Targeting the unfolded protein response in disease.

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Aldehyde dehydrogenase 2 ameliorates doxorubicin-induced myocardial dysfunction through detoxification of 4-HNE and suppression of autophagy

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Spliced X-box binding protein 1 couples the unfolded protein response to hexosamine biosynthetic pathway

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Autophagy and oxidative stress in cardiovascular diseases

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Connecting endoplasmic reticulum stress to autophagy through IRE1/JNK/beclin-1 in breast cancer cells

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Metabolic control of autophagy

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Rg1 exhibits neuroprotective effects by inhibiting the endoplasmic reticulum stress-mediated c-Jun N-terminal protein kinase apoptotic pathway in a rat model of Alzheimer's disease

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Regulation of endoplasmic reticulum turnover by selective autophagy

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12 December 2020

Mitochondrial calcium overload is a key determinant in heart failure.

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12 December 2020

ER stress: Autophagy induction, inhibition and selection.

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12 December 2020

Rg1 prevents myocardial hypoxia/reoxygenation injury by regulating mitochondrial dynamics imbalance via modulation of glutamate dehydrogenase and mitofusin 2.

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12 December 2020

Chemical Endoplasmic Reticulum Chaperone Alleviates Doxorubicin-Induced Cardiac Dysfunction

1 reference

12 December 2020

Ginsenoside Rg1 ameliorates diabetic cardiomyopathy by inhibiting endoplasmic reticulum stress-induced apoptosis in a streptozotocin-induced diabetes rat model

1 reference

12 December 2020

Inhibition of TNF-α-mediated NF-κB Activation by Ginsenoside Rg1 Contributes the Attenuation of Cardiac Hypertrophy Induced by Abdominal Aorta Coarctation

1 reference

12 December 2020

Rutin attenuates doxorubicin-induced cardiotoxicity via regulating autophagy and apoptosis.

1 reference

12 December 2020

Interferon alpha impairs insulin production in human beta cells via endoplasmic reticulum stress

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12 December 2020

Autophagy and mitophagy in the context of doxorubicin-induced cardiotoxicity.

1 reference

12 December 2020

Salvianolic acid B attenuates doxorubicin-induced ER stress by inhibiting TRPC3 and TRPC6 mediated Ca2 overload in rat cardiomyocytes

1 reference

12 December 2020

LCZ696 improves cardiac function via alleviating Drp1-mediated mitochondrial dysfunction in mice with doxorubicin-induced dilated cardiomyopathy

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12 December 2020

Fortunellin protects against high fructose-induced diabetic heart injury in mice by suppressing inflammation and oxidative stress via AMPK/Nrf-2 pathway regulation

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12 December 2020

Crosstalk of ER stress-mediated autophagy and ER-phagy: Involvement of UPR and the core autophagy machinery

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12 December 2020

Activation of γ2-AMPK Suppresses Ribosome Biogenesis and Protects Against Myocardial Ischemia/Reperfusion Injury.

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12 December 2020

Oral administration of Ginsenoside Rg1 prevents cardiac toxicity induced by doxorubicin in mice through anti-apoptosis

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12 December 2020

ER homeostasis and autophagy

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12 December 2020

Diazoxide Improves Mitochondrial Connexin 43 Expression in a Mouse Model of Doxorubicin-Induced Cardiotoxicity.

1 reference

12 December 2020

Eat it right: ER-phagy and recovER-phagy.

1 reference

12 December 2020

Mitochondrial calcium uniporter inhibition provides cardioprotection in pressure overload-induced heart failure through autophagy enhancement

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12 December 2020

Cardioprotective effects of autophagy: Eat your heart out, heart failure!

1 reference

12 December 2020

ER-phagy requires Lnp1, a protein that stabilizes rearrangements of the ER network

1 reference

12 December 2020

1 reference

12 December 2020

Inhibiting Receptor of Advanced Glycation End Products Attenuates Pressure Overload-Induced Cardiac Dysfunction by Preventing Excessive Autophagy

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12 December 2020

Identifiers

DOI

10.3390/IJMS19113658

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30463294 AND SRC:MED&resulttype=core&format=json

5 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30463294 AND SRC:MED&resulttype=core&format=json

5 May 2020

PubMed publication ID

30463294

1 reference