A multicenter phase II trial of 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (3-AP, Triapine®) and gemcitabine in advanced non-small-cell lung cancer with pharmacokinetic evaluation using peripheral blood mononuclear cells (Q59647299)

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scientific article published on 12 September 2007

Language	Label	Description	Also known as
English	A multicenter phase II trial of 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (3-AP, Triapine®) and gemcitabine in advanced non-small-cell lung cancer with pharmacokinetic evaluation using peripheral blood mononuclear cells	scientific article published on 12 September 2007

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17851637 AND SRC:MED&resulttype=core&format=json

7 January 2020

A multicenter phase II trial of 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (3-AP, Triapine) and gemcitabine in advanced non-small-cell lung cancer with pharmacokinetic evaluation using peripheral blood mononuclear cells (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17851637 AND SRC:MED&resulttype=core&format=json

7 January 2020

multicenter clinical trial

1 reference

based on heuristic

inferred from title

phase II clinical trial

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

pharmacokinetics

1 reference

based on heuristic

inferred from title

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17851637 AND SRC:MED&resulttype=core&format=json

7 January 2020

Anthony Tak-Cheung Chan

9

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17851637 AND SRC:MED&resulttype=core&format=json

7 January 2020

Benny Chung-Ying Zee

10

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17851637 AND SRC:MED&resulttype=core&format=json

7 January 2020

11

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17851637 AND SRC:MED&resulttype=core&format=json

7 January 2020

author name string

Boon Cher Goh

2

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17851637 AND SRC:MED&resulttype=core&format=json

7 January 2020

Eng Huat Tan

3

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17851637 AND SRC:MED&resulttype=core&format=json

7 January 2020

Kwok Chi Lam

4

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17851637 AND SRC:MED&resulttype=core&format=json

7 January 2020

Ross Soo

5

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17851637 AND SRC:MED&resulttype=core&format=json

7 January 2020

Swan Swan Leong

6

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17851637 AND SRC:MED&resulttype=core&format=json

7 January 2020

Ling Zhi Wang

7

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17851637 AND SRC:MED&resulttype=core&format=json

7 January 2020

Frankie Mo

8

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7 January 2020

publication date

12 September 2007

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7 January 2020

Investigational New Drugs

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17851637 AND SRC:MED&resulttype=core&format=json

7 January 2020

26

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17851637 AND SRC:MED&resulttype=core&format=json

7 January 2020

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17851637 AND SRC:MED&resulttype=core&format=json

7 January 2020

169-173

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17851637 AND SRC:MED&resulttype=core&format=json

7 January 2020

Phase II study of Triapine in patients with metastatic renal cell carcinoma: a trial of the National Cancer Institute of Canada Clinical Trials Group (NCIC IND.161)

1 reference

https://pubmed.ncbi.nlm.nih.gov/17851637

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methemoglobinemia after infusion of ifosfamide chemotherapy: first report of a potentially serious adverse reaction related to ifosfamide

1 reference

https://pubmed.ncbi.nlm.nih.gov/17851637

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recognition and management of methemoglobinemia and hemolysis in a G6PD-deficient patient on experimental anticancer drug Triapine

1 reference

https://pubmed.ncbi.nlm.nih.gov/17851637

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chelators at the cancer coalface: desferrioxamine to Triapine and beyond.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17851637

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada

1 reference

https://pubmed.ncbi.nlm.nih.gov/17851637

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Triapine (3-aminopyridine-2-carboxaldehyde- thiosemicarbazone): A potent inhibitor of ribonucleotide reductase activity with broad spectrum antitumor activity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17851637

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A multicentre randomised phase II study of carboplatin in combination with gemcitabine at standard rate or fixed dose rate infusion in patients with advanced stage non-small-cell lung cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17851637

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

One-sample multiple testing procedure for phase II clinical trials

1 reference

https://pubmed.ncbi.nlm.nih.gov/17851637

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An Expedient Assay for Determination of Gemcitabine and Its Metabolite in Human Plasma Using Isocratic Ion-Pair Reversed-Phase High-Performance Liquid Chromatography

1 reference

https://pubmed.ncbi.nlm.nih.gov/17851637

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methemoglobinemia: etiology, pharmacology, and clinical management

1 reference

https://pubmed.ncbi.nlm.nih.gov/17851637

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gemcitabine as second-line treatment for advanced non-small-cell lung cancer: A phase II trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/17851637

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Single-agent gemcitabine as second-line treatment in patients with advanced non small cell lung cancer (NSCLC): a phase II trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/17851637

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A phase I trial of 3-aminopyridine-2-carboxaldehyde thiosemicarbazone in combination with gemcitabine for patients with advanced cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/17851637

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two epithelial tumor cell lines (HNE-1 and HONE-1) latently infected with Epstein-Barr virus that were derived from nasopharyngeal carcinomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/17851637

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Second-line treatment of advanced non-small cell lung cancer with paclitaxel and gemcitabine: a preliminary report on an active regimen

1 reference

https://pubmed.ncbi.nlm.nih.gov/17851637

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S10637-007-9085-0

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17851637 AND SRC:MED&resulttype=core&format=json

7 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17851637 AND SRC:MED&resulttype=core&format=json

7 January 2020

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