The metalloproteinase matrilysin proteolytically generates active soluble Fas ligand and potentiates epithelial cell apoptosis (Q59276652)

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2 November 2019

title

The metalloproteinase matrilysin proteolytically generates active soluble Fas ligand and potentiates epithelial cell apoptosis (English)

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2 November 2019

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Barbara Mary Fingleton

2

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2 November 2019

author name string

W C Powell

1

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2 November 2019

C L Wilson

3

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2 November 2019

M Boothby

4

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2 November 2019

L M Matrisian

5

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2 November 2019

language of work or name

English

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publication date

1 December 1999

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2 November 2019

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10607586 AND SRC:MED&resulttype=core&format=json

2 November 2019

volume

9

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2 November 2019

issue

24

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2 November 2019

page(s)

1441-1447

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Apoptosis signaling by death receptors.

2 November 2019

cites work

1 reference

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7 January 2021

Fas and Fas ligand in embryos and adult mice: ligand expression in several immune-privileged tissues and coexpression in adult tissues characterized by apoptotic cell turnover

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7 January 2021

Fas ligand is not only expressed in immune privileged human organs but is also coexpressed with Fas in various epithelial tissues

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7 January 2021

Apoptosis, tumour invasion and prostate cancer

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Apoptosis and related genes in the rat ventral prostate following androgen ablation in response to ethane dimethanesulfonate

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7 January 2021

Fas antigen/CD-95 upregulation and activation during castration-induced regression of the rat ventral prostate gland

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7 January 2021

Metalloproteinase-mediated release of human Fas ligand

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7 January 2021

Regulation of cell surface APO-1/Fas (CD95) ligand expression by metalloproteases

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7 January 2021

Expression of the functional soluble form of human fas ligand in activated lymphocytes.

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7 January 2021

Conversion of membrane-bound Fas(CD95) ligand to its soluble form is associated with downregulation of its proapoptotic activity and loss of liver toxicity

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7 January 2021

Matrilysin expression in the involuting rat ventral prostate

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7 January 2021

Matrilysin: an epithelial matrix metalloproteinase with potentially novel functions

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7 January 2021

Processing of tumour necrosis factor-α precursor by metalloproteinases

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7 January 2021

Downregulation of Fas ligand by shedding

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7 January 2021

Fas ligand is present in tumors of the Ewing's sarcoma family and is cleaved into a soluble form by a metalloproteinase

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7 January 2021

A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells

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7 January 2021

Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-alpha

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7 January 2021

The mouse Fas-ligand gene is mutated in gld mice and is part of a TNF family gene cluster

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7 January 2021

FasL induces Fas/Apo1-mediated apoptosis in human embryonic kidney 293 cells routinely used to generate E1-deleted adenoviral vectors.

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7 January 2021

Matrix Metalloproteinase Matrilysin Is Constitutively Expressed in Adult Human Exocrine Epithelium

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7 January 2021

Intestinal tumorigenesis is suppressed in mice lacking the metalloproteinase matrilysin

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7 January 2021

Coordinate Expression of Matrix Metalloproteinase Family Members in the Uterus of Normal, Matrilysin-Deficient, and Stromelysin-1-Deficient Mice*

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7 January 2021

Suppression of ICE and apoptosis in mammary epithelial cells by extracellular matrix.

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7 January 2021

Rescue of mammary epithelial cell apoptosis and entactin degradation by a tissue inhibitor of metalloproteinases-1 transgene

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7 January 2021

MMP-9/gelatinase B is a key regulator of growth plate angiogenesis and apoptosis of hypertrophic chondrocytes

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7 January 2021

Mechanisms of spontaneous resolution of rat liver fibrosis. Hepatic stellate cell apoptosis and reduced hepatic expression of metalloproteinase inhibitors

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7 January 2021

Divergent effects of tissue inhibitor of metalloproteinase-1, -2, or -3 overexpression on rat vascular smooth muscle cell invasion, proliferation, and death in vitro. TIMP-3 promotes apoptosis

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7 January 2021

Disruption of epithelial cell-matrix interactions induces apoptosis

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7 January 2021

Rapid onset of apoptosis in vitro follows disruption of beta 1-integrin/matrix interactions in human colonic crypt cells.

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7 January 2021

Requirement of cell-cell contact in the induction of Jurkat T cell apoptosis: the membrane-anchored but not soluble form of FasL can trigger anti-CD3-induced apoptosis in Jurkat T cells

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7 January 2021

Transformation-dependent susceptibility of rat hepatic stellate cells to apoptosis induced by soluble Fas ligand

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7 January 2021

Diverse cell surface protein ectodomains are shed by a system sensitive to metalloprotease inhibitors.

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7 January 2021

Matrix metalloproteinase 2 releases active soluble ectodomain of fibroblast growth factor receptor 1.

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7 January 2021

Rapid identification of highly active and selective substrates for stromelysin and matrilysin using bacteriophage peptide display libraries

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https://api.crossref.org/works/10.1016/S0960-9822(00)80113-X

7 January 2021

Production, purification, and characterization of human matrilysin (PUMP) from recombinant Chinese hamster ovary cells

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7 January 2021

10.1016/S0960-9822(00)80113-X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10607586 AND SRC:MED&resulttype=core&format=json

2 November 2019

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