PDGF/PDGFR effects in osteosarcoma and the "add-on" strategy (Q58803894)

April 2022 Public Data File from Crossref

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30 November 2018

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30 November 2018

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30 November 2018

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Personalized comprehensive molecular profiling of high risk osteosarcoma: Implications and limitations for precision medicine

30 November 2018

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Osteosarcoma: Current Treatment and a Collaborative Pathway to Success

30 November 2018

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30 November 2018

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Sorafenib and everolimus for patients with unresectable high-grade osteosarcoma progressing after standard treatment: a non-randomised phase 2 clinical trial.

30 November 2018

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Role of mesenchymal stem cells in osteosarcoma and metabolic reprogramming of tumor cells.

30 November 2018

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PDGF receptors in tumor biology: prognostic and predictive potential

30 November 2018

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Theranostic Profiling for Actionable Aberrations in Advanced High Risk Osteosarcoma with Aggressive Biology Reveals High Molecular Diversity: The Human Fingerprint Hypothesis

30 November 2018

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Drug repurposing identifies a synergistic combination therapy with imatinib mesylate for gastrointestinal stromal tumor

30 November 2018

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Phase I study of olaratumab in Japanese patients with advanced solid tumors

30 November 2018

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Imatinib mesylate exerts anti-proliferative effects on osteosarcoma cells and inhibits the tumour growth in immunocompetent murine models

30 November 2018

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30 November 2018

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30 November 2018

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Chemoresistance to gemcitabine in hepatoma cells induces epithelial-mesenchymal transition and involves activation of PDGF-D pathway

30 November 2018

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PDGF/PDGFR signaling and targeting in cancer growth and progression: Focus on tumor microenvironment and cancer-associated fibroblasts

30 November 2018

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30 November 2018

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30 November 2018

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30 November 2018

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Multitargeted receptor tyrosine kinase inhibition: An antiangiogenic strategy in non-small cell lung cancer

30 November 2018

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A phase II trial of sorafenib in relapsed and unresectable high-grade osteosarcoma after failure of standard multimodal therapy: an Italian Sarcoma Group study

30 November 2018

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Expression of platelet-derived growth factor-alpha receptor in human osteosarcoma is not a predictor of outcome.

30 November 2018

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Correlation between clinical outcome and growth factor pathway expression in osteogenic sarcoma

30 November 2018

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Development of a fully human anti-PDGFRbeta antibody that suppresses growth of human tumor xenografts and enhances antitumor activity of an anti-VEGFR2 antibody

30 November 2018

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Phase II multicenter trial of imatinib in 10 histologic subtypes of sarcoma using a bayesian hierarchical statistical model.

30 November 2018

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Cancer-associated fibroblasts and tumor growth--bystanders turning into key players

30 November 2018

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Osteosarcoma incidence and survival rates from 1973 to 2004: data from the Surveillance, Epidemiology, and End Results Program

30 November 2018

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Neoadjuvant chemotherapy for osteosarcoma of the extremities in preadolescent patients: the Rizzoli Institute experience

30 November 2018

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Tumour hypoxia affects the responsiveness of cancer cells to chemotherapy and promotes cancer progression

30 November 2018

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Role of platelet-derived growth factors in physiology and medicine

30 November 2018

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Platelet-derived growth factor receptor as a prognostic marker and a therapeutic target for imatinib mesylate therapy in osteosarcoma

30 November 2018

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Functions of paracrine PDGF signaling in the proangiogenic tumor stroma revealed by pharmacological targeting

30 November 2018

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Combined antiproliferative activity of imatinib mesylate (STI-571) with radiation or cisplatin in vitro.

30 November 2018

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Platelet-derived growth factor receptor-alpha: a novel therapeutic target in human hepatocellular cancer.

30 November 2018

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A phase II study of imatinib mesylate in children with refractory or relapsed solid tumors: a Children's Oncology Group study

30 November 2018

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Targeting the expression of platelet-derived growth factor receptor by reactive stroma inhibits growth and metastasis of human colon carcinoma.

30 November 2018

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Multidrug resistance mediated by ABC transporters in osteosarcoma cell lines: mRNA analysis and functional radiotracer studies

30 November 2018

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Tumor-driven paracrine platelet-derived growth factor receptor alpha signaling is a key determinant of stromal cell recruitment in a model of human lung carcinoma

30 November 2018

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30 November 2018

Fibroblasts in cancer

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30 November 2018

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Targeting the platelet-derived growth factor receptor alpha with a neutralizing human monoclonal antibody inhibits the growth of tumor xenografts: implications as a potential therapeutic target

30 November 2018

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Blockade of platelet-derived growth factor receptor-beta by CDP860, a humanized, PEGylated di-Fab', leads to fluid accumulation and is associated with increased tumor vascularized volume.

30 November 2018

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VEGF-null cells require PDGFR alpha signaling-mediated stromal fibroblast recruitment for tumorigenesis

30 November 2018

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30 November 2018

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SB-431542 and Gleevec inhibit transforming growth factor-beta-induced proliferation of human osteosarcoma cells

30 November 2018

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STI571 enhances the therapeutic index of epothilone B by a tumor-selective increase of drug uptake

30 November 2018

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Growth inhibition of rat osteosarcoma and malignant fibrous histiocytoma cells by tyrosine kinase inhibitor STI571.

30 November 2018

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Tumour hypoxia, chemotherapeutic resistance and hypoxia-related therapies.

30 November 2018

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Platelet-derived growth factor-B enhances glioma angiogenesis by stimulating vascular endothelial growth factor expression in tumor endothelia and by promoting pericyte recruitment

30 November 2018

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Inhibition of platelet-derived growth factor-mediated proliferation of osteosarcoma cells by the novel tyrosine kinase inhibitor STI571.

30 November 2018

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Inhibition of PDGF receptor signaling in tumor stroma enhances antitumor effect of chemotherapy

30 November 2018

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Control of interstitial fluid pressure: role of beta1-integrins.

30 November 2018

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Inhibition of platelet-derived growth factor receptors reduces interstitial hypertension and increases transcapillary transport in tumors

30 November 2018

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Basis of hematopoietic defects in platelet-derived growth factor (PDGF)-B and PDGF beta-receptor null mice

30 November 2018

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Mechanism of action and in vivo role of platelet-derived growth factor

30 November 2018

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Redundancy of autocrine loops in human osteosarcoma cells.

30 November 2018

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Full Activation of the Platelet-derived Growth Factor β-Receptor Kinase Involves Multiple Events

30 November 2018

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Treatment of Osteosarcoma 1972-1997: An American Perspective

30 November 2018

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Tumorigenic conversion of immortal human keratinocytes through stromal cell activation

30 November 2018

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CGP 57148, a tyrosine kinase inhibitor, inhibits the growth of cells expressing BCR-ABL, TEL-ABL, and TEL-PDGFR fusion proteins

30 November 2018

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Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells

30 November 2018

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Platelet-derived growth factor (PDGF) in oncogenesis: development of a vascular connective tissue stroma in xenotransplanted human melanoma producing PDGF-BB

30 November 2018

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Human osteoblasts synthesize and respond to platelet-derived growth factor

30 November 2018

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Expression of growth factors and their receptors in human osteosarcomas. Immunohistochemical detection of epidermal growth factor, platelet-derived growth factor and their receptors: its correlation with proliferating activities and p53 expression

30 November 2018

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12 December 2020

A novel physiological function for platelet-derived growth factor-BB in rat dermis

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12 December 2020

Platelet-derived growth factor-AA and -alpha receptor expression suggests an autocrine and/or paracrine loop in osteosarcoma

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12 December 2020

Expression of platelet-derived growth factor-AA is associated with tumor progression in osteosarcoma

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12 December 2020

Cell type-specific effect of hypoxia and platelet-derived growth factor-BB on extracellular matrix turnover and its consequences for lung remodeling.

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12 December 2020

Inhibiting platelet-derived growth factor beta reduces Ewing's sarcoma growth and metastasis in a novel orthotopic human xenograft model

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12 December 2020

Cytotoxic activity of fucoxanthin, alone and in combination with the cancer drugs imatinib and doxorubicin, in CML cell lines

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12 December 2020