HCN Channels: New Therapeutic Targets for Pain Treatment (Q58696173)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30134541 AND SRC:MED&resulttype=core&format=json

19 April 2020

review article

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title

HCN Channels: New Therapeutic Targets for Pain Treatment (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30134541 AND SRC:MED&resulttype=core&format=json

19 April 2020

1 reference

15 December 2019

1

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19 April 2020

author name string

Rafael Zúñiga

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2

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19 April 2020

Guierdy Concha

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3

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19 April 2020

Leandro Zúñiga

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4

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19 April 2020

language of work or name

English

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publication date

21 August 2018

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15 December 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30134541 AND SRC:MED&resulttype=core&format=json

19 April 2020

2 references

15 December 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30134541 AND SRC:MED&resulttype=core&format=json

19 April 2020

volume

23

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19 April 2020

issue

9

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Creative Commons Attribution

19 April 2020

page(s)

2094

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copyright license

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15 December 2019

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Increased HCN Channel Activity in the Gasserian Ganglion Contributes to Trigeminal Neuropathic Pain

1 reference

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Selective HCN1 block as a strategy to control oxaliplatin-induced neuropathy.

30 November 2018

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Hyperpolarization-activated cyclic nucleotide-gated 2 (HCN2) ion channels drive pain in mouse models of diabetic neuropathy.

30 November 2018

1 reference

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Gabapentin Modulates HCN4 Channel Voltage-Dependence.

30 November 2018

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[EXPRESS] Ion channels and neuronal hyperexcitability in chemotherapy-induced peripheral neuropathy; cause and effect?

30 November 2018

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Side Fenestrations Provide an "Anchor" for a Stable Binding of A1899 to the Pore of TASK-1 Potassium Channels

30 November 2018

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Structures of the Human HCN1 Hyperpolarization-Activated Channel

30 November 2018

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Essential roles of AMPA receptor GluA1 phosphorylation and presynaptic HCN channels in fast-acting antidepressant responses of ketamine

30 November 2018

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Computational Methods Applied to Rational Drug Design.

30 November 2018

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Expression and cellular localization of HCN channels in rat cerebellar granule neurons.

30 November 2018

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Inhibition of HCN channel activity in the thalamus attenuates chronic pain in rats.

30 November 2018

1 reference

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Voltage-Gated Ion Channels in the PNS: Novel Therapies for Neuropathic Pain?

30 November 2018

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Novel N-allyl/propargyl tetrahydroquinolines: Synthesis via Three-component Cationic Imino Diels-Alder Reaction, Binding Prediction, and Evaluation as Cholinesterase Inhibitors.

30 November 2018

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Neuropeptide S modulates the amygdaloidal HCN activities (Ih) in rats: Implication in chronic pain

30 November 2018

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Isoform dependent regulation of human HCN channels by cholesterol

30 November 2018

1 reference

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Peripheral Neuropathy Induces HCN Channel Dysfunction in Pyramidal Neurons of the Medial Prefrontal Cortex

30 November 2018

1 reference

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HCN1 Channels Contribute to the Effects of Amnesia and Hypnosis but not Immobility of Volatile Anesthetics

30 November 2018

1 reference

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HCN1 Channels as Targets for Volatile Anesthetics: Coming to the Fore

30 November 2018

1 reference

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Diabetic neuropathic pain: Physiopathology and treatment

30 November 2018

1 reference

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Impact of Hyperpolarization-activated, Cyclic Nucleotide-gated Cation Channel Type 2 for the Xenon-mediated Anesthetic Effect: Evidence from In Vitro and In Vivo Experiments

30 November 2018

1 reference

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HCN channels--modulators of cardiac and neuronal excitability

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6225464

Coexistence of two forms of LTP in ACC provides a synaptic mechanism for the interactions between anxiety and chronic pain

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6225464

Role of the TREK2 potassium channel in cold and warm thermosensation and in pain perception

30 November 2018

1 reference

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Inflammatory and neuropathic pain are rapidly suppressed by peripheral block of hyperpolarisation-activated cyclic nucleotide-gated ion channels

30 November 2018

1 reference

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Cyclic dinucleotides bind the C-linker of HCN4 to control channel cAMP responsiveness

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6225464

Cyclic nucleotide mapping of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels

30 November 2018

1 reference

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Enhanced excitability of primary sensory neurons and altered gene expression of neuronal ion channels in dorsal root ganglion in paclitaxel-induced peripheral neuropathy

30 November 2018

1 reference

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Opening paths to novel analgesics: the role of potassium channels in chronic pain

30 November 2018

1 reference

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Neurophysiology of HCN channels: from cellular functions to multiple regulations

30 November 2018

1 reference

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Chronic pain epidemiology and its clinical relevance

30 November 2018

1 reference

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Protein kinase C activation inhibits rat and human hyperpolarization activated cyclic nucleotide gated channel (HCN)1--mediated current in mammalian cells

30 November 2018

1 reference

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HCN1 channels as targets for anesthetic and nonanesthetic propofol analogs in the amelioration of mechanical and thermal hyperalgesia in a mouse model of neuropathic pain.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6225464

Inhibition of HCN channels within the periaqueductal gray attenuates neuropathic pain in rats

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6225464

Forebrain HCN1 channels contribute to hypnotic actions of ketamine

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6225464

The role of HCN channels within the periaqueductal gray in neuropathic pain

30 November 2018

1 reference

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HCN channels: function and clinical implications

30 November 2018

1 reference

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Identification of the molecular site of ivabradine binding to HCN4 channels

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6225464

Enhancement of dorsal hippocampal activity by knockdown of HCN1 channels leads to anxiolytic- and antidepressant-like behaviors

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6225464

HCN2 ion channels: an emerging role as the pacemakers of pain

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6225464

Exploring HCN channels as novel drug targets

30 November 2018

1 reference

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Novel blockers of hyperpolarization-activated current with isoform selectivity in recombinant cells and native tissue

30 November 2018

1 reference

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Tetramerization dynamics of C-terminal domain underlies isoform-specific cAMP gating in hyperpolarization-activated cyclic nucleotide-gated channels

30 November 2018

1 reference

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Discovery of a pharmacologically active antagonist of the two-pore-domain potassium channel K2P9.1 (TASK-3).

30 November 2018

1 reference

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Computational electrophysiology: the molecular dynamics of ion channel permeation and selectivity in atomistic detail

30 November 2018

1 reference

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Inhibition of spinal cord dorsal horn neuronal activity by electrical stimulation of the cerebellar cortex

30 November 2018

1 reference

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Towards an integrated view of HCN channel role in epilepsy.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6225464

PIP2-mediated HCN3 channel gating is crucial for rhythmic burst firing in thalamic intergeniculate leaflet neurons.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6225464

Oxaliplatin-induced cold hypersensitivity is due to remodelling of ion channel expression in nociceptors.

30 November 2018

1 reference

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Local Anesthetic Inhibits Hyperpolarization-Activated Cationic Currents

30 November 2018

1 reference

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Deep bradycardia and heart block caused by inducible cardiac-specific knockout of the pacemaker channel gene Hcn4

30 November 2018

1 reference

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HCN channels in behavior and neurological disease: Too hyper or not active enough?

30 November 2018

1 reference

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HCN channelopathy in external globus pallidus neurons in models of Parkinson's disease.

30 November 2018

1 reference

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Central mechanisms of pathological pain

30 November 2018

1 reference

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Nociceptor sensitization in pain pathogenesis

30 November 2018

1 reference

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Design, synthesis, and preliminary biological evaluation of new isoform-selective f-current blockers

30 November 2018

1 reference

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Interdependence of receptor activation and ligand binding in HCN2 pacemaker channels

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6225464

Spinal hyperpolarization-activated cyclic nucleotide-gated cation channels at primary afferent terminals contribute to chronic pain

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6225464

Hyperpolarization-activated ion channels as targets for nitric oxide signalling in deep cerebellar nuclei

30 November 2018

1 reference

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HCN-related channelopathies.

30 November 2018

1 reference

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Hyperpolarization-activated cation channels: from genes to function

30 November 2018

1 reference

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Mapping the structure and conformational movements of proteins with transition metal ion FRET

30 November 2018

1 reference

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Current strategies for the discovery of K channel modulators

30 November 2018

1 reference

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Inflammation-induced increase in hyperpolarization-activated, cyclic nucleotide-gated channel protein in trigeminal ganglion neurons and the effect of buprenorphine

30 November 2018

1 reference

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HCN1 channel subunits are a molecular substrate for hypnotic actions of ketamine

30 November 2018

1 reference

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Subunit-specific effects of isoflurane on neuronal Ih in HCN1 knockout mice

30 November 2018

1 reference

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HCN channels: structure, cellular regulation and physiological function

30 November 2018

1 reference

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Role of the hyperpolarization-activated current Ih in somatosensory neurons

30 November 2018

1 reference

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General anaesthesia: from molecular targets to neuronal pathways of sleep and arousal

30 November 2018

1 reference

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C-terminal Movement during Gating in Cyclic Nucleotide-modulated Channels

30 November 2018

1 reference

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Novel pharmacological activity of loperamide and CP-339,818 on human HCN channels characterized with an automated electrophysiology assay

30 November 2018

1 reference

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Src tyrosine kinase alters gating of hyperpolarization-activated HCN4 pacemaker channel through Tyr531.

30 November 2018

1 reference

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Prevalence of chronic pain with neuropathic characteristics in the general population.

30 November 2018

1 reference

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alpha2-Noradrenergic receptors activation enhances excitability and synaptic integration in rat prefrontal cortex pyramidal neurons via inhibition of HCN currents

30 November 2018

1 reference

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Molecular mapping of the binding site for a blocker of hyperpolarization-activated, cyclic nucleotide-modulated pacemaker channels

30 November 2018

1 reference

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Direct inhibition of cardiac hyperpolarization-activated cyclic nucleotide-gated pacemaker channels by clonidine

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6225464

Pacemaking by HCN channels requires interaction with phosphoinositides

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6225464

Regulation of gating and rundown of HCN hyperpolarization-activated channels by exogenous and endogenous PIP2

30 November 2018

1 reference

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Calcium influx through If channels in rat ventricular myocytes.

30 November 2018

1 reference

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Constitutively active Src tyrosine kinase changes gating of HCN4 channels through direct binding to the channel proteins

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6225464

Evaluation of HCN2 abnormalities as a cause of juvenile audiogenic seizures in Black Swiss mice.

30 November 2018

1 reference

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CNG and HCN channels: two peas, one pod.

30 November 2018

1 reference

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Propofol block of I(h) contributes to the suppression of neuronal excitability and rhythmic burst firing in thalamocortical neurons

30 November 2018

1 reference

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Bradycardic and proarrhythmic properties of sinus node inhibitors

30 November 2018

1 reference

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Hyperpolarization-activated cation current (Ih) is an ethanol target in midbrain dopamine neurons of mice

30 November 2018

1 reference

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Survey of chronic pain in Europe: Prevalence, impact on daily life, and treatment

30 November 2018

1 reference

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Suppression of ih contributes to propofol-induced inhibition of mouse cortical pyramidal neurons

30 November 2018

1 reference

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Functional expression of the human HCN3 channel

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6225464

Impairment of hyperpolarization-activated, cyclic nucleotide-gated channel function by the intravenous general anesthetic propofol.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6225464

HCN subunit-specific and cAMP-modulated effects of anesthetics on neuronal pacemaker currents.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6225464

A homology model of the pore region of HCN channels.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6225464

Preferential localization of the hyperpolarization-activated cyclic nucleotide-gated cation channel subunit HCN1 in basket cell terminals of the rat cerebellum

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6225464

Inhibition of hyperpolarization-activated current by ZD7288 suppresses ectopic discharges of injured dorsal root ganglion neurons in a rat model of neuropathic pain

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6225464

Regulation of recombinant and native hyperpolarization-activated cation channels.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6225464

Molecular and neuronal substrates for general anaesthetics

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6225464

Hyperpolarization-activated, cyclic nucleotide-gated cation channels: roles in the differential electrophysiological properties of rat primary afferent neurons

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6225464

Immunohistochemical localization of Ih channel subunits, HCN1-4, in the rat brain

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6225464

Calcium influx through hyperpolarization-activated cation channels (I(h) channels) contributes to activity-evoked neuronal secretion

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6225464

Pacemaker channels and sinus node arrhythmia

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6225464

The hyperpolarization-activated HCN1 channel is important for motor learning and neuronal integration by cerebellar Purkinje cells

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6225464

Pentobarbital modulates intrinsic and GABA-receptor conductances in thalamocortical inhibition

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6225464

The process of structure-based drug design

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6225464

Structural basis for modulation and agonist specificity of HCN pacemaker channels

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6225464

Role of subunit heteromerization and N-linked glycosylation in the formation of functional hyperpolarization-activated cyclic nucleotide-gated channels

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6225464

Serotonin reduces the hyperpolarization-activated current (Ih) in ventral tegmental area dopamine neurons: involvement of 5-HT2 receptors and protein kinase C.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6225464

Molecular basis for the different activation kinetics of the pacemaker channels HCN2 and HCN4

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6225464

The principle of gating charge movement in a voltage-dependent K channel

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6225464

Neuronal hyperpolarization-activated pacemaker channels drive neuropathic pain.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6225464

Gabapentin increases the hyperpolarization-activated cation current Ih in rat CA1 pyramidal cells

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6225464

Molecular modeling of ion channels: structural predictions

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6225464

Absence epilepsy and sinus dysrhythmia in mice lacking the pacemaker channel HCN2

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6225464

Activity-dependent regulation of HCN pacemaker channels by cyclic AMP: signaling through dynamic allosteric coupling

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6225464

Convergent and reciprocal modulation of a leak K current and I(h) by an inhalational anaesthetic and neurotransmitters in rat brainstem motoneurones

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6225464

Chemistry of ion coordination and hydration revealed by a K channel-Fab complex at 2.0 A resolution

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6225464

Molecular mechanism of cAMP modulation of HCN pacemaker channels.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6225464

Dendritic mechanisms of phase precession in hippocampal CA1 pyramidal neurons

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6225464

Dendritic integration of excitatory synaptic input

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6225464

Cellular expression and functional characterization of four hyperpolarization-activated pacemaker channels in cardiac and neuronal tissues

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6225464

A single histidine residue determines the pH sensitivity of the pacemaker channel HCN2.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6225464

Functional roles of charged residues in the putative voltage sensor of the HCN2 pacemaker channel.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6225464

Mutations in the S4 domain of a pacemaker channel alter its voltage dependence

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6225464

Molecular and functional heterogeneity of hyperpolarization-activated pacemaker channels in the mouse CNS.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6225464

The voltage sensor in voltage-dependent ion channels

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6225464

Dendritic voltage-gated ion channels regulate the action potential firing mode of hippocampal CA1 pyramidal neurons

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6225464

Differential distribution of four hyperpolarization-activated cation channels in mouse brain

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6225464

Modulation of the hyperpolarization-activated cation current of rat thalamic relay neurones by intracellular pH.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6225464

Dendritic lh normalizes temporal summation in hippocampal CA1 neurons

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6225464

Distribution and prevalence of hyperpolarization-activated cation channel (HCN) mRNA expression in cardiac tissues

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6225464

Two pacemaker channels from human heart with profoundly different activation kinetics

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6225464

Ca2 permeation in cyclic nucleotide-gated channels

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6225464

Multiple ionic mechanisms mediate inhibition of rat motoneurones by inhalation anaesthetics

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6225464

A family of hyperpolarization-activated mammalian cation channels

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6225464

Molecular identification of a hyperpolarization-activated channel in sea urchin sperm

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6225464

Identification of a gene encoding a hyperpolarization-activated pacemaker channel of brain

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6225464

Fractional contribution of calcium to the cation current through glutamate receptor channels

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6225464

Fractional calcium currents through recombinant GluR channels of the NMDA, AMPA and kainate receptor subtypes

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6225464

Volatile anaesthetics inhibit a cyclic AMP-dependent sodium-potassium current in cultured sensory neurones of bullfrog

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6225464

Direct activation of cardiac pacemaker channels by intracellular cyclic AMP.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6225464

Calcium permeability of nicotinic acetylcholine receptor channels in bovine adrenal chromaffin cells

30 November 2018

1 reference

12 December 2020

Ca2 influx via the L-type Ca2 channel during tail current and above current reversal potential in ferret ventricular myocytes

1 reference

12 December 2020

Role of peripheral hyperpolarization-activated cyclic nucleotide-modulated channel pacemaker channels in acute and chronic pain models in the rat

1 reference

12 December 2020

HCN pacemaker channel activation is controlled by acidic lipids downstream of diacylglycerol kinase and phospholipase A2

1 reference

12 December 2020

Direct inhibition of Ih by analgesic loperamide in rat DRG neurons

1 reference

12 December 2020

Genetic analysis of hyperpolarization-activated cyclic nucleotide-gated cation channels in sudden unexpected death in epilepsy cases

1 reference

12 December 2020

Discovery of a novel series of selective HCN1 blockers

1 reference

12 December 2020

HCN2 Ion Channels Play a Central Role in Inflammatory and Neuropathic Pain

1 reference

12 December 2020

How subunits cooperate in cAMP-induced activation of homotetrameric HCN2 channels

1 reference

12 December 2020

Chronic inflammatory pain is associated with increased excitability and hyperpolarization-activated current (Ih) in C- but not Aδ-nociceptors

1 reference

12 December 2020

The heart-rate-reducing agent, ivabradine, reduces mechanical allodynia in a rodent model of neuropathic pain

1 reference

12 December 2020

Dexmedetomidine produced analgesic effect via inhibition of HCN currents

1 reference

12 December 2020

Increased expression of HCN2 channel protein in L4 dorsal root ganglion neurons following axotomy of L5- and inflammation of L4-spinal nerves in rats

1 reference

12 December 2020

All four subunits of HCN2 channels contribute to the activation gating in an additive but intricate manner

1 reference

12 December 2020

10.3390/MOLECULES23092094

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30134541 AND SRC:MED&resulttype=core&format=json

19 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30134541 AND SRC:MED&resulttype=core&format=json

19 April 2020

PubMed publication ID

30134541

1 reference