Integrative regulation of physiology by histone deacetylase 3 (Q58617588)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30390028 AND SRC:MED&resulttype=core&format=json

1 May 2020

title

Integrative regulation of physiology by histone deacetylase 3 (English)

1 reference

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1 May 2020

author name string

Matthew J Emmett

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30390028 AND SRC:MED&resulttype=core&format=json

1 May 2020

Mitchell A Lazar

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30390028 AND SRC:MED&resulttype=core&format=json

1 May 2020

language of work or name

English

0 references

publication date

1 February 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30390028 AND SRC:MED&resulttype=core&format=json

Nature Reviews Molecular Cell Biology

1 May 2020

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30390028 AND SRC:MED&resulttype=core&format=json

1 May 2020

volume

20

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30390028 AND SRC:MED&resulttype=core&format=json

1 May 2020

issue

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30390028 AND SRC:MED&resulttype=core&format=json

1 May 2020

page(s)

102-115

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Enhancer function: new insights into the regulation of tissue-specific gene expression

1 May 2020

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The many roles of histone deacetylases in development and physiology: implications for disease and therapy

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A mammalian histone deacetylase related to the yeast transcriptional regulator Rpd3p

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Histone deacetylase activity of Rpd3 is important for transcriptional repression in vivo

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HDA1 and RPD3 are members of distinct yeast histone deacetylase complexes that regulate silencing and transcription

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Molecular evolution of the histone deacetylase family: functional implications of phylogenetic analysis.

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Unraveling the hidden catalytic activity of vertebrate class IIa histone deacetylases

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Conserved metabolic regulatory functions of sirtuins

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SIRT1 and other sirtuins in metabolism

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Sirtuins mediate mammalian metabolic responses to nutrient availability

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7 January 2021

Erasers of histone acetylation: the histone deacetylase enzymes

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7 January 2021

New and emerging HDAC inhibitors for cancer treatment

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7 January 2021

Both corepressor proteins SMRT and N-CoR exist in large protein complexes containing HDAC3

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7 January 2021

The histone deacetylase-3 complex contains nuclear receptor corepressors

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7 January 2021

Cell-specific integration of nuclear receptor function at the genome

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7 January 2021

Nuclear receptors and the control of metabolism

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7 January 2021

Controlling nuclear receptors: the circular logic of cofactor cycles

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7 January 2021

Nuclear receptors and metabolism: from feast to famine

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7 January 2021

The CoRNR motif controls the recruitment of corepressors by nuclear hormone receptors

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7 January 2021

Deconstructing repression: evolving models of co-repressor action

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7 January 2021

Purification and functional characterization of the human N-CoR complex: the roles of HDAC3, TBL1 and TBLR1

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7 January 2021

The N-CoR-HDAC3 nuclear receptor corepressor complex inhibits the JNK pathway through the integral subunit GPS2

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7 January 2021

A complex containing N-CoR, mSin3 and histone deacetylase mediates transcriptional repression

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7 January 2021

Nuclear receptor repression mediated by a complex containing SMRT, mSin3A, and histone deacetylase

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7 January 2021

Molecular determinants of nuclear receptor-corepressor interaction

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7 January 2021

The SMRT and N-CoR corepressors are activating cofactors for histone deacetylase 3

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7 January 2021

The nuclear receptor corepressor deacetylase activating domain is essential for repression by thyroid hormone receptor

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7 January 2021

Structural insights into the interaction and activation of histone deacetylase 3 by nuclear receptor corepressors.

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7 January 2021

Essential role for the SANT domain in the functioning of multiple chromatin remodeling enzymes

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7 January 2021

The SANT domain: a unique histone-tail-binding module?

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7 January 2021

A SANT motif in the SMRT corepressor interprets the histone code and promotes histone deacetylation

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7 January 2021

Structure of HDAC3 bound to co-repressor and inositol tetraphosphate

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Nuclear receptor co-repressors are required for the histone-deacetylase activity of HDAC3 in vivo

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New lives for old: evolution of pseudoenzyme function illustrated by iRhoms.

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Regulated clearance of histone deacetylase 3 protects independent formation of nuclear receptor corepressor complexes.

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7 January 2021

Assembly of the SMRT-histone deacetylase 3 repression complex requires the TCP-1 ring complex

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7 January 2021

Deacetylase-independent function of HDAC3 in transcription and metabolism requires nuclear receptor corepressor

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7 January 2021

Deletion of histone deacetylase 3 reveals critical roles in S phase progression and DNA damage control

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7 January 2021

Maintenance of cardiac energy metabolism by histone deacetylase 3 in mice

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7 January 2021

Nuclear receptor corepressor and histone deacetylase 3 govern circadian metabolic physiology

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

Regulation of histone deacetylase activities

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

Nuclear receptor coregulators: judges, juries, and executioners of cellular regulation

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

Regulation of histone deacetylase 2 by protein kinase CK2.

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

Histone deacetylase 3 (HDAC3) activity is regulated by interaction with protein serine/threonine phosphatase 4.

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

Liver-specific deletion of histone deacetylase 3 disrupts metabolic transcriptional networks

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

Histone deacetylase 3 down-regulates cholesterol synthesis through repression of lanosterol synthase gene expression

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

Hepatic Hdac3 promotes gluconeogenesis by repressing lipid synthesis and sequestration

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

A Circadian Rhythm Orchestrated by Histone Deacetylase 3 Controls Hepatic Lipid Metabolism

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

Stoichiometric and steric principles governing repression by nuclear hormone receptors

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

Determinants of CoRNR-dependent repression complex assembly on nuclear hormone receptors

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

Rev-erbα and Rev-erbβ coordinately protect the circadian clock and normal metabolic function

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

Rev-erbα dynamically modulates chromatin looping to control circadian gene transcription.

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

GENE REGULATION. Discrete functions of nuclear receptor Rev-erbα couple metabolism to the clock.

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

An HDAC3-PROX1 corepressor module acts on HNF4α to control hepatic triglycerides

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

Histone deacetylase 3 prepares brown adipose tissue for acute thermogenic challenge.

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

Mice lacking mitochondrial uncoupling protein are cold-sensitive but not obese

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

Orphan nuclear receptor estrogen-related receptor alpha is essential for adaptive thermogenesis

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https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

Transcriptional control of energy homeostasis by the estrogen-related receptors

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https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

Reduced fat mass in mice lacking orphan nuclear receptor estrogen-related receptor alpha

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https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

The transcriptional coactivator PGC-1 regulates the expression and activity of the orphan nuclear receptor estrogen-related receptor alpha (ERRalpha).

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7 January 2021

1 reference

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7 January 2021

ERRγ Preserves Brown Fat Innate Thermogenic Activity.

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

Transcriptional control of brown fat determination by PRDM16

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

Repression of Adipose Tissue Fibrosis through a PRDM16-GTF2IRD1 Complex Improves Systemic Glucose Homeostasis

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

Cellular Aging Contributes to Failure of Cold-Induced Beige Adipocyte Formation in Old Mice and Humans

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

HDAC3 is a molecular brake of the metabolic switch supporting white adipose tissue browning

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

The nuclear-envelope protein and transcriptional repressor LAP2beta interacts with HDAC3 at the nuclear periphery, and induces histone H4 deacetylation

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

How to make a heart: the origin and regulation of cardiac progenitor cells

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

Histone deacetylase 3 modulates Tbx5 activity to regulate early cardiogenesis

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

Histone Deacetylase 3 Coordinates Deacetylase-independent Epigenetic Silencing of Transforming Growth Factor-β1 (TGF-β1) to Orchestrate Second Heart Field Development

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

Genome-Nuclear Lamina Interactions Regulate Cardiac Stem Cell Lineage Restriction

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

The Nuclear Envelope Protein Emerin Binds Directly to Histone Deacetylase 3 (HDAC3) and Activates HDAC3 Activity

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

DNA sequence-dependent compartmentalization and silencing of chromatin at the nuclear lamina

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

Competent for commitment: you've got to have heart!

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

Birth prevalence of congenital heart disease worldwide: a systematic review and meta-analysis

1 reference

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7 January 2021

A syndrome of altered cardiovascular, craniofacial, neurocognitive and skeletal development caused by mutations in TGFBR1 or TGFBR2

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7 January 2021

Dysregulation of TGF-beta activation contributes to pathogenesis in Marfan syndrome

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7 January 2021

Histone Deacetylase 3 Regulates Smooth Muscle Differentiation in Neural Crest Cells and Development of the Cardiac Outflow Tract

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7 January 2021

Diet-induced Lethality Due to Deletion of the Hdac3 Gene in Heart and Skeletal Muscle

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7 January 2021

Cardiac nuclear receptors: architects of mitochondrial structure and function

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https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

PGC-1 coactivators: inducible regulators of energy metabolism in health and disease

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

Histone deacetylase 3 is necessary for proper brain development

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

Hdac3 Interaction with p300 Histone Acetyltransferase Regulates the Oligodendrocyte and Astrocyte Lineage Fate Switch

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

A histone deacetylase 3-dependent pathway delimits peripheral myelin growth and functional regeneration

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

HDAC3 Is a Critical Negative Regulator of Long-Term Memory Formation

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

HDAC3 is a negative regulator of cocaine-context-associated memory formation

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

Activity-dependent phosphorylation of MeCP2 threonine 308 regulates interaction with NCoR.

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

Rett syndrome mutations abolish the interaction of MeCP2 with the NCoR/SMRT co-repressor

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

Histone deacetylase 3 associates with MeCP2 to regulate FOXO and social behavior.

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

HDAC3-Dependent Epigenetic Pathway Controls Lung Alveolar Epithelial Cell Remodeling and Spreading via miR-17-92 and TGF-β Signaling Regulation

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

Expression of histone deacetylase 3 instructs alveolar type I cell differentiation by regulating a Wnt signaling niche in the lung

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

Histone deacetylase 3 coordinates commensal-bacteria-dependent intestinal homeostasis

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

Epithelial Histone Deacetylase 3 Instructs Intestinal Immunity by Coordinating Local Lymphocyte Activation.

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

Disruption of Epithelial HDAC3 in Intestine Prevents Diet-induced Obesity in Mice.

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

Deletion of histone deacetylase 3 in adult beta cells improves glucose tolerance via increased insulin secretion

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

Histone deacetylase 3 inhibition improves glycaemia and insulin secretion in obese diabetic rats

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

Inhibition of Histone Deacetylase 3 Protects Beta Cells from Cytokine-Induced Apoptosis

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

Histone deacetylases 1 and 3 but not 2 mediate cytokine-induced beta cell apoptosis in INS-1 cells and dispersed primary islets from rats and are differentially regulated in the islets of type 1 diabetic children

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

Conditional ablation of HDAC3 in islet beta cells results in glucose intolerance and enhanced susceptibility to STZ-induced diabetes

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

Pancreas-specific Cre driver lines and considerations for their prudent use

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

Brain expression of Cre recombinase driven by pancreas-specific promoters.

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

Dissociation of muscle insulin sensitivity from exercise endurance in mice by HDAC3 depletion

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

Histone deacetylase 3 is an epigenomic brake in macrophage alternative activation.

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

Requirement for the histone deacetylase Hdac3 for the inflammatory gene expression program in macrophages

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

Targeting macrophage Histone deacetylase 3 stabilizes atherosclerotic lesions.

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

Hdac3 Is Essential for the Maintenance of Chromatin Structure and Genome Stability

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

HDAC3 is essential for DNA replication in hematopoietic progenitor cells.

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

Deacetylase activity of histone deacetylase 3 is required for productive VDJ recombination and B-cell development

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

Histone Deacetylase 3 Is Required for Efficient T Cell Development

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

HDAC3 Is Required for the Downregulation of RORγt during Thymocyte Positive Selection

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

Histone Deacetylase 3 Is Required for T Cell Maturation

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

Autophagy: a druggable process that is deregulated in aging and human disease

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

Duration of nuclear NF-kappaB action regulated by reversible acetylation

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

Histone Deacetylases in Bone Development and Skeletal Disorders.

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

Murine craniofacial development requires Hdac3-mediated repression of Msx gene expression

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

Histone deacetylase 3 depletion in osteo/chondroprogenitor cells decreases bone density and increases marrow fat

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

Histone Deacetylase 3 Deletion in Mesenchymal Progenitor Cells Hinders Long Bone Development

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

Histone deacetylase 3 supports endochondral bone formation by controlling cytokine signaling and matrix remodeling

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

Histone deacetylase 3 is required for maintenance of bone mass during aging

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

Histone deacetylase 3 interacts with runx2 to repress the osteocalcin promoter and regulate osteoblast differentiation

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

Runx2 protein represses Axin2 expression in osteoblasts and is required for craniosynostosis in Axin2-deficient mice

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

Zfp521 controls bone mass by HDAC3-dependent attenuation of Runx2 activity

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

Teratogenic activity of HDAC inhibitors

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

The effect of valproate on bone mineral density in adult epileptic patients

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

Long-term valproate and lamotrigine treatment may be a marker for reduced growth and bone mass in children with epilepsy

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

Bone mineral metabolism changes in epileptic children receiving valproic acid.

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

Decreased bone mass and increased bone turnover with valproate therapy in adults with epilepsy

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

Craniosynostosis and fetal exposure to sodium valproate

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

Preaxial ray reduction defects as part of valproic acid embryofetopathy

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

The Effects of Class-Specific Histone Deacetylase Inhibitors on the Development of Limbs During Organogenesis

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

Effect of natural genetic variation on enhancer selection and function.

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

Hdac3 regulates lymphovenous and lymphatic valve formation.

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

Enhancer biology and enhanceropathies

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

GCN5 acetyltransferase complex controls glucose metabolism through transcriptional repression of PGC-1alpha

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

Ebf2 is a selective marker of brown and beige adipogenic precursor cells

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

EBF2 transcriptionally regulates brown adipogenesis via the histone reader DPF3 and the BAF chromatin remodeling complex

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

Cross-platform normalization of microarray and RNA-seq data for machine learning applications

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

limma powers differential expression analyses for RNA-sequencing and microarray studies

1 reference

https://api.crossref.org/works/10.1038/S41580-018-0076-0

7 January 2021

The SANT domain: a putative DNA-binding domain in the SWI-SNF and ADA complexes, the transcriptional co-repressor N-CoR and TFIIIB.

1 reference

12 December 2020

Nuclear receptor coregulators: cellular and molecular biology

1 reference

12 December 2020

Nuclear receptor corepressors partner with class II histone deacetylases in a Sin3-independent repression pathway

1 reference

12 December 2020

Isolation of a novel histone deacetylase reveals that class I and class II deacetylases promote SMRT-mediated repression

1 reference

12 December 2020

The coregulator exchange in transcriptional functions of nuclear receptors

1 reference

12 December 2020

A core SMRT corepressor complex containing HDAC3 and TBL1, a WD40-repeat protein linked to deafness

1 reference

12 December 2020

FOXP3 regulatory T cell development and function require histone/protein deacetylase 3.

1 reference

12 December 2020

A map of the PGC-1α- and NT-PGC-1α-regulated transcriptional network in brown adipose tissue.

1 reference

12 December 2020

10.1038/S41580-018-0076-0

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30390028 AND SRC:MED&resulttype=core&format=json

1 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30390028 AND SRC:MED&resulttype=core&format=json

1 May 2020

PubMed publication ID

30390028

1 reference